| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ciclacillin-4358 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACO2 | aconitase 2, mitochondrial |
| ACPP | acid phosphatase, prostate |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADORA1 | adenosine A1 receptor |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APC2 | adenomatosis polyposis coli 2 |
| APOL2 | apolipoprotein L, 2 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| B9D1 | B9 protein domain 1 |
| CAMKV | CaM kinase-like vesicle-associated |
| CCR7 | chemokine (C-C motif) receptor 7 |
| CD22 | CD22 molecule |
| CHD5 | chromodomain helicase DNA binding protein 5 |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| CPA4 | carboxypeptidase A4 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DOK4 | docking protein 4 |
| DUSP9 | dual specificity phosphatase 9 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM129A | family with sequence similarity 129, member A |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FRMD1 | FERM domain containing 1 |
| GABRG2 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
| GAS7 | growth arrest-specific 7 |
| GLI2 | GLI family zinc finger 2 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HHAT | hedgehog acyltransferase |
| HIST3H3 | histone cluster 3, H3 |
| HLF | hepatic leukemia factor |
| HPX | hemopexin |
| HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IL23A | interleukin 23, alpha subunit p19 |
| INHBA | inhibin, beta A |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 |
| KIAA1456 | KIAA1456 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| KRT75 | keratin 75, type II |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LAT2 | linker for activation of T cells family, member 2 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MC5R | melanocortin 5 receptor |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MST1 | macrophage stimulating 1 |
| NPHP1 | nephronophthisis 1 (juvenile) |
| NPR3 | natriuretic peptide receptor 3 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHACTR1 | phosphatase and actin regulator 1 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLCD1 | phospholipase C, delta 1 |
| PLXNB1 | plexin B1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PURA | purine-rich element binding protein A |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RPH3A | rabphilin 3A |
| RPLP2 | ribosomal protein, large, P2 |
| RUNX2 | runt-related transcription factor 2 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCN4A | sodium channel, voltage gated, type IV alpha subunit |
| SCRG1 | stimulator of chondrogenesis 1 |
| SERHL2 | serine hydrolase-like 2 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SLC12A3 | solute carrier family 12 (sodium/chloride transporter), member 3 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SPEG | SPEG complex locus |
| STAC | SH3 and cysteine rich domain |
| TAGLN3 | transgelin 3 |
| TDRD12 | tudor domain containing 12 |
| TMEM206 | transmembrane protein 206 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| WSCD1 | WSC domain containing 1 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF423 | zinc finger protein 423 |
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| ADCY7 | adenylate cyclase 7 |
| AMDHD2 | amidohydrolase domain containing 2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| BAGE | B melanoma antigen |
| BBS7 | Bardet-Biedl syndrome 7 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC69 | coiled-coil domain containing 69 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNO | cyclin O |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDH18 | cadherin 18, type 2 |
| CDK20 | cyclin-dependent kinase 20 |
| CFHR4 | complement factor H-related 4 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNTFR | ciliary neurotrophic factor receptor |
| CORO7 | coronin 7 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNM3 | dynamin 3 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EGFL7 | EGF-like-domain, multiple 7 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EXOC6B | exocyst complex component 6B |
| FAM198B | family with sequence similarity 198, member B |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FOXI1 | forkhead box I1 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GPR143 | G protein-coupled receptor 143 |
| HDAC5 | histone deacetylase 5 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H3B | histone cluster 1, H3b |
| HOXA4 | homeobox A4 |
| HSPA1L | heat shock 70kDa protein 1-like |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA1107 | KIAA1107 |
| KRT24 | keratin 24, type I |
| LAMP3 | lysosomal-associated membrane protein 3 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MANBA | mannosidase, beta A, lysosomal |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MTCP1 | mature T-cell proliferation 1 |
| MYL5 | myosin, light chain 5, regulatory |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NOL10 | nucleolar protein 10 |
| NOTCH1 | notch 1 |
| ONECUT2 | one cut homeobox 2 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PGP | phosphoglycolate phosphatase |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PRR14L | proline rich 14-like |
| PRR4 | proline rich 4 (lacrimal) |
| PSCA | prostate stem cell antigen |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RGS19 | regulator of G-protein signaling 19 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RND1 | Rho family GTPase 1 |
| RPL10L | ribosomal protein L10-like |
| RUNDC3B | RUN domain containing 3B |
| S100A7 | S100 calcium binding protein A7 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SMIM14 | small integral membrane protein 14 |
| SOAT2 | sterol O-acyltransferase 2 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STRA6 | stimulated by retinoic acid 6 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TEX40 | testis expressed 40 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEM121 | transmembrane protein 121 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VIM | vimentin |
| WFDC2 | WAP four-disulfide core domain 2 |
| XAB2 | XPA binding protein 2 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF286A | zinc finger protein 286A |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
