cicloheximide-3464 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cicloheximide-3464 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
AMOTL2 angiomotin like 2
ARID4A AT rich interactive domain 4A (RBP1-like)
ATF3 activating transcription factor 3
BCOR BCL6 corepressor
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
BRAP BRCA1 associated protein
C7ORF43 chromosome 7 open reading frame 43
CDKN2AIP CDKN2A interacting protein
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLCF1 cardiotrophin-like cytokine factor 1
CSF1 colony stimulating factor 1 (macrophage)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DENND4C DENN/MADD domain containing 4C
DLX2 distal-less homeobox 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DTNA dystrobrevin, alpha
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPHA2 EPH receptor A2
EPHA4 EPH receptor A4
EPHB3 EPH receptor B3
FLRT3 fibronectin leucine rich transmembrane protein 3
FRMD4B FERM domain containing 4B
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H2AC histone cluster 1, H2ac
HIST1H2AG histone cluster 1, H2ag
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BC histone cluster 1, H2bc
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H2BH histone cluster 1, H2bh
HIST1H2BI histone cluster 1, H2bi
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H3H histone cluster 1, H3h
HIST1H4H histone cluster 1, H4h
HIST2H2BE histone cluster 2, H2be
HIST3H2A histone cluster 3, H2a
HOXC13 homeobox C13
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
INTS6 integrator complex subunit 6
IRF1 interferon regulatory factor 1
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KIAA0513 KIAA0513
KLF10 Kruppel-like factor 10
KLF5 Kruppel-like factor 5 (intestinal)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MT1F metallothionein 1F
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OVOL1 ovo-like zinc finger 1
OVOL2 ovo-like zinc finger 2
PER1 period circadian clock 1
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTCH1 patched 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCOR3 REST corepressor 3
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
SERTAD2 SERTA domain containing 2
SIDT1 SID1 transmembrane family, member 1
SLC16A6 solute carrier family 16, member 6
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SOCS2 suppressor of cytokine signaling 2
SOX9 SRY (sex determining region Y)-box 9
SPRY4 sprouty homolog 4 (Drosophila)
SRCAP Snf2-related CREBBP activator protein
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCHH trichohyalin
TGFA transforming growth factor, alpha
TGFB2 transforming growth factor, beta 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
VIPR1 vasoactive intestinal peptide receptor 1
ZMYM5 zinc finger, MYM-type 5
ZNF329 zinc finger protein 329
ZNF750 zinc finger protein 750
ZXDC ZXD family zinc finger C

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ADGRA3 adhesion G protein-coupled receptor A3
AGBL5 ATP/GTP binding protein-like 5
AGGF1 angiogenic factor with G patch and FHA domains 1
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
ALAS1 5'-aminolevulinate synthase 1
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ASB13 ankyrin repeat and SOCS box containing 13
ASTN2 astrotactin 2
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BMP4 bone morphogenetic protein 4
BPGM 2,3-bisphosphoglycerate mutase
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF80 chromosome 11 open reading frame 80
C1ORF174 chromosome 1 open reading frame 174
C5AR2 complement component 5a receptor 2
CAMTA2 calmodulin binding transcription activator 2
CANT1 calcium activated nucleotidase 1
CCNG1 cyclin G1
CCNI cyclin I
CHPF2 chondroitin polymerizing factor 2
COCH cochlin
CORT cortistatin
CSK c-src tyrosine kinase
DEAF1 DEAF1 transcription factor
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
E2F6 E2F transcription factor 6
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR3 early growth response 3
ERCC6L excision repair cross-complementation group 6-like
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EVL Enah/Vasp-like
FAM102A family with sequence similarity 102, member A
FAM172A family with sequence similarity 172, member A
FAM20B family with sequence similarity 20, member B
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GPBP1L1 GC-rich promoter binding protein 1-like 1
GPR137B G protein-coupled receptor 137B
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA8 heat shock 70kDa protein 8
INSIG1 insulin induced gene 1
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0125 KIAA0125
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MAP6D1 MAP6 domain containing 1
MCM3AP-AS1 MCM3AP antisense RNA 1
MCRS1 microspherule protein 1
MREG melanoregulin
MRS2 MRS2 magnesium transporter
MTIF2 mitochondrial translational initiation factor 2
MXI1 MAX interactor 1, dimerization protein
NCK2 NCK adaptor protein 2
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NLK nemo-like kinase
NPY1R neuropeptide Y receptor Y1
NR1H2 nuclear receptor subfamily 1, group H, member 2
OAZ2 ornithine decarboxylase antizyme 2
OPN3 opsin 3
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDZK1 PDZ domain containing 1
PHTF1 putative homeodomain transcription factor 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRKX protein kinase, X-linked
RAB8B RAB8B, member RAS oncogene family
RAD54L RAD54-like (S. cerevisiae)
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RGS19 regulator of G-protein signaling 19
RHOBTB1 Rho-related BTB domain containing 1
RNF141 ring finger protein 141
RNF38 ring finger protein 38
RNF44 ring finger protein 44
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL13P5 ribosomal protein L13 pseudogene 5
RPUSD2 RNA pseudouridylate synthase domain containing 2
SACS sacsin molecular chaperone
SH2B3 SH2B adaptor protein 3
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC38A2 solute carrier family 38, member 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SPINK4 serine peptidase inhibitor, Kazal type 4
STARD7 StAR-related lipid transfer (START) domain containing 7
STK16 serine/threonine kinase 16
TESK2 testis-specific kinase 2
TMEM243 transmembrane protein 243, mitochondrial
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNNT1 troponin T type 1 (skeletal, slow)
TRAK2 trafficking protein, kinesin binding 2
TUBA3C tubulin, alpha 3c
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UNKL unkempt family zinc finger-like
WRB tryptophan rich basic protein
XBP1 X-box binding protein 1
ZMAT3 zinc finger, matrin-type 3
ZNF32 zinc finger protein 32