| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ciclopirox-2456 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADM | adrenomedullin |
| AGRN | agrin |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATF3 | activating transcription factor 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTG2 | BTG family, member 2 |
| CD59 | CD59 molecule, complement regulatory protein |
| CD69 | CD69 molecule |
| CD83 | CD83 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP5 | dual specificity phosphatase 5 |
| DUSP8 | dual specificity phosphatase 8 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EGR4 | early growth response 4 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EIF5 | eukaryotic translation initiation factor 5 |
| FADS3 | fatty acid desaturase 3 |
| FAM53C | family with sequence similarity 53, member C |
| FCAR | Fc fragment of IgA receptor |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FLT1 | fms-related tyrosine kinase 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL1 | FOS-like antigen 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| ICAM1 | intercellular adhesion molecule 1 |
| IER3 | immediate early response 3 |
| IL1B | interleukin 1, beta |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| LDLR | low density lipoprotein receptor |
| LRRC23 | leucine rich repeat containing 23 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta |
| MCL1 | myeloid cell leukemia 1 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1M | metallothionein 1M |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| NAMPT | nicotinamide phosphoribosyltransferase |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NFYA | nuclear transcription factor Y, alpha |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLIN2 | perilipin 2 |
| PLK3 | polo-like kinase 3 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB13 | RAB13, member RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS16 | regulator of G-protein signaling 16 |
| RHOB | ras homolog family member B |
| RND1 | Rho family GTPase 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOCS1 | suppressor of cytokine signaling 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SQSTM1 | sequestosome 1 |
| TAT | tyrosine aminotransferase |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TEX14 | testis expressed 14 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIB1 | tribbles pseudokinase 1 |
| TUBB2A | tubulin, beta 2A class IIa |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| ZFP36 | ZFP36 ring finger protein |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF10 | zinc finger protein 10 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADRB2 | adrenoceptor beta 2, surface |
| AIM1 | absent in melanoma 1 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AMT | aminomethyltransferase |
| ANKRD55 | ankyrin repeat domain 55 |
| ANXA2P2 | annexin A2 pseudogene 2 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| APOLD1 | apolipoprotein L domain containing 1 |
| B3GNT1 | |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| BSPRY | B-box and SPRY domain containing |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C5 | complement component 5 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CBX7 | chromobox homolog 7 |
| CDC20 | cell division cycle 20 |
| CDC7 | cell division cycle 7 |
| CES3 | carboxylesterase 3 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DEPDC1 | DEP domain containing 1 |
| DIXDC1 | DIX domain containing 1 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| ELMO1 | engulfment and cell motility 1 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ERI2 | ERI1 exoribonuclease family member 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FANCF | Fanconi anemia, complementation group F |
| FCHO1 | FCH domain only 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GFI1 | growth factor independent 1 transcription repressor |
| GIMAP6 | GTPase, IMAP family member 6 |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H4C | histone cluster 1, H4c |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA4L | heat shock 70kDa protein 4-like |
| IFI6 | interferon, alpha-inducible protein 6 |
| IRF8 | interferon regulatory factor 8 |
| KIAA0319L | KIAA0319-like |
| KIF20A | kinesin family member 20A |
| KIF23 | kinesin family member 23 |
| KIF4A | kinesin family member 4A |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LIMD2 | LIM domain containing 2 |
| MANSC1 | MANSC domain containing 1 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MXD3 | MAX dimerization protein 3 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NFE2 | nuclear factor, erythroid 2 |
| NINJ2 | ninjurin 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLK1 | polo-like kinase 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| POLL | polymerase (DNA directed), lambda |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PRAF2 | PRA1 domain family, member 2 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAD9A | RAD9 homolog A (S. pombe) |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RNF144A | ring finger protein 144A |
| RWDD2A | RWD domain containing 2A |
| SKI | SKI proto-oncogene |
| SLA | Src-like-adaptor |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| STK16 | serine/threonine kinase 16 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TFEC | transcription factor EC |
| THBS4 | thrombospondin 4 |
| TJP2 | tight junction protein 2 |
| TMEM187 | transmembrane protein 187 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA4B | tubulin, alpha 4b |
| VANGL1 | VANGL planar cell polarity protein 1 |
| WDR62 | WD repeat domain 62 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF528 | zinc finger protein 528 |
| ZNF606 | zinc finger protein 606 |
