| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ciclopirox-3317 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ALDOC | aldolase C, fructose-bisphosphate |
| ANGPTL4 | angiopoietin-like 4 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ATF3 | activating transcription factor 3 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BLNK | B-cell linker |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BTG2 | BTG family, member 2 |
| CCNG2 | cyclin G2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEL | carboxyl ester lipase |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| DAPK2 | death-associated protein kinase 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DTNA | dystrobrevin, alpha |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EFNA3 | ephrin-A3 |
| EGFR | epidermal growth factor receptor |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERO1L | ERO1-like (S. cerevisiae) |
| FAM162A | family with sequence similarity 162, member A |
| FAM212B | family with sequence similarity 212, member B |
| FAS | Fas cell surface death receptor |
| FCMR | Fc fragment of IgM receptor |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 |
| GPR87 | G protein-coupled receptor 87 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HK2 | hexokinase 2 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| INHBE | inhibin, beta E |
| INSIG2 | insulin induced gene 2 |
| KDM3A | lysine (K)-specific demethylase 3A |
| LIF | leukemia inhibitory factor |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK7 | mitogen-activated protein kinase 7 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MR1 | major histocompatibility complex, class I-related |
| MST1 | macrophage stimulating 1 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MXI1 | MAX interactor 1, dimerization protein |
| N4BP3 | NEDD4 binding protein 3 |
| NDRG1 | N-myc downstream regulated 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PGM1 | phosphoglucomutase 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PLK3 | polo-like kinase 3 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB6B | RAB6B, member RAS oncogene family |
| RGS20 | regulator of G-protein signaling 20 |
| RNF19B | ring finger protein 19B |
| RRAGD | Ras-related GTP binding D |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SESN1 | sestrin 1 |
| SFXN3 | sideroflexin 3 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPAG4 | sperm associated antigen 4 |
| STC1 | stanniocalcin 1 |
| TMEM45A | transmembrane protein 45A |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF395 | zinc finger protein 395 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTL8 | actin-like 8 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARL4A | ADP-ribosylation factor-like 4A |
| ARMC4 | armadillo repeat containing 4 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| AURKA | aurora kinase A |
| AURKB | aurora kinase B |
| BORA | bora, aurora kinase A activator |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CALML5 | calmodulin-like 5 |
| CCNB1 | cyclin B1 |
| CDC20 | cell division cycle 20 |
| CDC25B | cell division cycle 25B |
| CDCA3 | cell division cycle associated 3 |
| CDCA8 | cell division cycle associated 8 |
| CENPA | centromere protein A |
| CENPE | centromere protein E, 312kDa |
| CENPF | centromere protein F, 350/400kDa |
| CERS4 | ceramide synthase 4 |
| CIC | capicua transcriptional repressor |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| DEPDC1 | DEP domain containing 1 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EFHD2 | EF-hand domain family, member D2 |
| EPHA4 | EPH receptor A4 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FAM111A | family with sequence similarity 111, member A |
| FAM64A | family with sequence similarity 64, member A |
| FER | fer (fps/fes related) tyrosine kinase |
| GMPR | guanosine monophosphate reductase |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| H1F0 | H1 histone family, member 0 |
| H2AFJ | H2A histone family, member J |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H4C | histone cluster 1, H4c |
| HJURP | Holliday junction recognition protein |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA2 | heat shock 70kDa protein 2 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IRX5 | iroquois homeobox 5 |
| KIAA0754 | KIAA0754 |
| KIF11 | kinesin family member 11 |
| KIF14 | kinesin family member 14 |
| KIF18A | kinesin family member 18A |
| KIF18B | kinesin family member 18B |
| KIF20A | kinesin family member 20A |
| KIF23 | kinesin family member 23 |
| KIF4A | kinesin family member 4A |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRRC20 | leucine rich repeat containing 20 |
| MED9 | mediator complex subunit 9 |
| METTL16 | methyltransferase like 16 |
| MKI67 | marker of proliferation Ki-67 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDC80 | NDC80 kinetochore complex component |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| PARPBP | PARP1 binding protein |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLK1 | polo-like kinase 1 |
| PRC1 | protein regulator of cytokinesis 1 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| RACGAP1 | Rac GTPase activating protein 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF121 | ring finger protein 121 |
| RNF43 | ring finger protein 43 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC4A1AP | solute carrier family 4 (anion exchanger), member 1, adaptor protein |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| TMEM104 | transmembrane protein 104 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPX2 | TPX2, microtubule-associated |
| TROAP | trophinin associated protein |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| ZNF134 | zinc finger protein 134 |
| ZNF165 | zinc finger protein 165 |
