| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ciclopirox-6677 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADM | adrenomedullin |
| ANGPTL4 | angiopoietin-like 4 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARG2 | arginase 2 |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BEND5 | BEN domain containing 5 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CCDC71 | coiled-coil domain containing 71 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CHD5 | chromodomain helicase DNA binding protein 5 |
| CRYAB | crystallin, alpha B |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DTNA | dystrobrevin, alpha |
| DUSP1 | dual specificity phosphatase 1 |
| EFNA3 | ephrin-A3 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EGR1 | early growth response 1 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPHB3 | EPH receptor B3 |
| FAM13A | family with sequence similarity 13, member A |
| FBXL8 | F-box and leucine-rich repeat protein 8 |
| FLT1 | fms-related tyrosine kinase 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GLRX | glutaredoxin (thioltransferase) |
| GRB10 | growth factor receptor-bound protein 10 |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HK2 | hexokinase 2 |
| HOXD10 | homeobox D10 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| ICAM1 | intercellular adhesion molecule 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| INSIG2 | insulin induced gene 2 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KITLG | KIT ligand |
| KLF4 | Kruppel-like factor 4 (gut) |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LIMK2 | LIM domain kinase 2 |
| LOX | lysyl oxidase |
| MXI1 | MAX interactor 1, dimerization protein |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NCOR2 | nuclear receptor corepressor 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NOX1 | NADPH oxidase 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDLIM4 | PDZ and LIM domain 4 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PIAS2 | protein inhibitor of activated STAT, 2 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLIN2 | perilipin 2 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| RAB20 | RAB20, member RAS oncogene family |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| SAP30 | Sin3A-associated protein, 30kDa |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC43A3 | solute carrier family 43, member 3 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STC1 | stanniocalcin 1 |
| STC2 | stanniocalcin 2 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TMEM45A | transmembrane protein 45A |
| TMEM74B | transmembrane protein 74B |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TRIM9 | tripartite motif containing 9 |
| WISP1 | WNT1 inducible signaling pathway protein 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF395 | zinc finger protein 395 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADRB2 | adrenoceptor beta 2, surface |
| AEN | apoptosis enhancing nuclease |
| ALPK1 | alpha-kinase 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BCL7A | B-cell CLL/lymphoma 7A |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CDC25B | cell division cycle 25B |
| CDCA8 | cell division cycle associated 8 |
| CEP72 | centrosomal protein 72kDa |
| CHRDL1 | chordin-like 1 |
| CISH | cytokine inducible SH2-containing protein |
| CLSPN | claspin |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ERCC2 | excision repair cross-complementation group 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMIP | GEM interacting protein |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPC3 | glypican 3 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HOXA1 | homeobox A1 |
| HOXA9 | homeobox A9 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0922 | KIAA0922 |
| KLHL36 | kelch-like family member 36 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP3K7CL | MAP3K7 C-terminal like |
| MGP | matrix Gla protein |
| MMP3 | matrix metallopeptidase 3 |
| MTRF1 | mitochondrial translational release factor 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OSR2 | odd-skipped related transciption factor 2 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PER3 | period circadian clock 3 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PLA1A | phospholipase A1 member A |
| PLAU | plasminogen activator, urokinase |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PYCARD | PYD and CARD domain containing |
| RAB40A | RAB40A, member RAS oncogene family |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF39 | ring finger protein 39 |
| RPH3A | rabphilin 3A |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SIRT6 | sirtuin 6 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TLR2 | toll-like receptor 2 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| UGT8 | UDP glycosyltransferase 8 |
| USP20 | ubiquitin specific peptidase 20 |
| XYLT2 | xylosyltransferase II |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF214 | zinc finger protein 214 |
| ZNF219 | zinc finger protein 219 |
| ZNF274 | zinc finger protein 274 |
| ZNF385D | zinc finger protein 385D |
| ZNF408 | zinc finger protein 408 |
| ZNF606 | zinc finger protein 606 |
