ciclopirox Gene Set

Dataset	CTD Gene-Chemical Interactions
Category	physical interactions
Type	chemical
Description	1-Hydroxypyridin-2(1H)-one in which the hydrogens at positions 4 and 6 are substituted by methyl and cyclohexyl groups, repectively. A broad spectrum antigfungal agent, it also exhibits antibacterial activity against many Gram-positive and Gram-negative bacteria, and has anti-inflammatory properties. It is used a a topical treatment of fungal skin and nail infections. (Chemical Entities of Biological Interest Ontology, CHEBI_453011)
External Link	http://ctdbase.org/detail.go?type=chem&acc=C011585
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Genes

10 genes/proteins interacting with the chemical ciclopirox from the curated CTD Gene-Chemical Interactions dataset.

Symbol	Name
BIRC5	baculoviral IAP repeat containing 5
FLT4	fms-related tyrosine kinase 4
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1	heme oxygenase 1
KCNH2	potassium channel, voltage gated eag related subfamily H, member 2
MAPK1	mitogen-activated protein kinase 1
MAPK3	mitogen-activated protein kinase 3
MAPT	microtubule-associated protein tau
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
RRM2	ribonucleotide reductase M2