cilium Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body. (Gene Ontology, GO_0005929)
External Link http://amigo.geneontology.org/amigo/term/GO:0005929
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Genes

403 proteins localized to the cilium cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
ADCY10 adenylate cyclase 10 (soluble)
ADCY5 adenylate cyclase 5
ADCY8 adenylate cyclase 8 (brain)
ADCY9 adenylate cyclase 9
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADORA1 adenosine A1 receptor
ADRB2 adrenoceptor beta 2, surface
AGTPBP1 ATP/GTP binding protein 1
AHI1 Abelson helper integration site 1
AKAP4 A kinase (PRKA) anchor protein 4
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALPK1 alpha-kinase 1
ALPK3 alpha-kinase 3
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3
ANO10 anoctamin 10
ANXA1 annexin A1
ARHGAP1 Rho GTPase activating protein 1
ARL13A ADP-ribosylation factor-like 13A
ARL13B ADP-ribosylation factor-like 13B
ARL2 ADP-ribosylation factor-like 2
ARL3 ADP-ribosylation factor-like 3
ARL6 ADP-ribosylation factor-like 6
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATXN10 ataxin 10
AXDND1 axonemal dynein light chain domain containing 1
BBIP1 BBSome interacting protein 1
BBS1 Bardet-Biedl syndrome 1
BBS2 Bardet-Biedl syndrome 2
BBS4 Bardet-Biedl syndrome 4
BBS5 Bardet-Biedl syndrome 5
BBS7 Bardet-Biedl syndrome 7
BBS9 Bardet-Biedl syndrome 9
BEST2 bestrophin 2
BMP2 bone morphogenetic protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRWD1 bromodomain and WD repeat domain containing 1
CABS1 calcium-binding protein, spermatid-specific 1
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CADPS2 Ca++-dependent secretion activator 2
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CATSPERB catsper channel auxiliary subunit beta
CATSPERG catsper channel auxiliary subunit gamma
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC14 coiled-coil domain containing 14
CCDC39 coiled-coil domain containing 39
CCDC40 coiled-coil domain containing 40
CCDC66 coiled-coil domain containing 66
CCSAP centriole, cilia and spindle-associated protein
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEP104 centrosomal protein 104kDa
CEP131 centrosomal protein 131kDa
CEP19 centrosomal protein 19kDa
CEP20 centrosomal protein 20
CEP41 centrosomal protein 41kDa
CEP89 centrosomal protein 89kDa
CFAP100 cilia and flagella associated protein 100
CFAP126 cilia and flagella associated protein 126
CFAP161 cilia and flagella associated protein 161
CFAP20 cilia and flagella associated protein 20
CFAP206 cilia and flagella associated protein 206
CFAP221 cilia and flagella associated protein 221
CFAP251 cilia and flagella associated protein 251
CFAP300 cilia and flagella associated protein 300
CFAP45 cilia and flagella associated protein 45
CFAP47 cilia and flagella associated protein 47
CFAP53 cilia and flagella associated protein 53
CFAP61 cilia and flagella associated protein 61
CFAP68 cilia and flagella associated protein 68
CFAP69 cilia and flagella associated protein 69
CFAP70 cilia and flagella associated protein 70
CFAP73 cilia and flagella associated protein 73
CFAP91 cilia and flagella associated protein 91
CHRM2 cholinergic receptor, muscarinic 2
CILK1 ciliogenesis associated kinase 1
CIMIP1 ciliary microtubule inner protein 1
CKAP2 cytoskeleton associated protein 2
CKAP2L cytoskeleton associated protein 2-like
CKAP5 cytoskeleton associated protein 5
CLNS1A chloride channel, nucleotide-sensitive, 1A
CLXN calaxin
CNGA2 cyclic nucleotide gated channel alpha 2
CNGA4 cyclic nucleotide gated channel alpha 4
CNGB1 cyclic nucleotide gated channel beta 1
CSNK1A1 casein kinase 1, alpha 1
CSNK1D casein kinase 1, delta
CSPP1 centrosome and spindle pole associated protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYRIB CYFIP related Rac1 interactor B
CYS1 cystin 1
DAAM1 dishevelled associated activator of morphogenesis 1
DAPK3 death-associated protein kinase 3
DAW1 dynein assembly factor with WDR repeat domains 1
DCDC2 doublecortin domain containing 2
DCTN1 dynactin 1
DLEC1 deleted in lung and esophageal cancer 1
DNAAF11 dynein axonemal assembly factor 11
DNAAF2 dynein, axonemal, assembly factor 2
DNAAF5 dynein, axonemal, assembly factor 5
DNAH11 dynein, axonemal, heavy chain 11
DNAH2 dynein, axonemal, heavy chain 2
DNAH5 dynein, axonemal, heavy chain 5
DNAH7 dynein, axonemal, heavy chain 7
DNAH9 dynein, axonemal, heavy chain 9
DNAI1 dynein, axonemal, intermediate chain 1
DNAI4 dynein axonemal intermediate chain 4
DNAI7 dynein axonemal intermediate chain 7
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13
DNALI1 dynein, axonemal, light intermediate chain 1
DPYSL2 dihydropyrimidinase-like 2
DRC3 dynein regulatory complex subunit 3
DRC7 dynein regulatory complex subunit 7
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD5 dopamine receptor D5
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYNC2I1 dynein 2 intermediate chain 1
DYNC2I2 dynein 2 intermediate chain 2
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
DYNLRB1 dynein, light chain, roadblock-type 1
DYNLRB2 dynein, light chain, roadblock-type 2
DZIP1L DAZ interacting zinc finger protein 1-like
EFCAB7 EF-hand calcium binding domain 7
EGFR epidermal growth factor receptor
EHD1 EH-domain containing 1
EML4 echinoderm microtubule associated protein like 4
ENKD1 enkurin domain containing 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ERICH3 glutamate-rich 3
EVC Ellis van Creveld protein
EVC2 Ellis van Creveld syndrome 2
EVI2A ecotropic viral integration site 2A
FAN1 FANCD2/FANCI-associated nuclease 1
FANK1 fibronectin type III and ankyrin repeat domains 1
FBF1 Fas (TNFRSF6) binding factor 1
FFAR4 free fatty acid receptor 4
FHDC1 FH2 domain containing 1
FLCN folliculin
FUZ fuzzy planar cell polarity protein
FZD4 frizzled class receptor 4
FZD6 frizzled class receptor 6
GABARAPL1 GABA(A) receptor-associated protein like 1
GALR2 galanin receptor 2
GALR3 galanin receptor 3
GAS8 growth arrest-specific 8
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GPR157 G protein-coupled receptor 157
GPR161 G protein-coupled receptor 161
GPR19 G protein-coupled receptor 19
GPR83 G protein-coupled receptor 83
GPR88 G protein-coupled receptor 88
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRHL3 grainyhead-like 3 (Drosophila)
GRK2 G protein-coupled receptor kinase 2
GUCA1B guanylate cyclase activator 1B (retina)
HAUS3 HAUS augmin-like complex, subunit 3
HAVCR1 hepatitis A virus cellular receptor 1
HHIP hedgehog interacting protein
HOATZ HOATZ cilia and flagella associated protein
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPB11 heat shock protein family B (small), member 11
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
HYDIN HYDIN, axonemal central pair apparatus protein
HYLS1 hydrolethalus syndrome 1
IFT122 intraflagellar transport 122
IFT140 intraflagellar transport 140
IFT172 intraflagellar transport 172
IFT20 intraflagellar transport 20
IFT22 intraflagellar transport 22
IFT27 intraflagellar transport 27
IFT38 intraflagellar transport 38
IFT43 intraflagellar transport 43
IFT46 intraflagellar transport 46
IFT52 intraflagellar transport 52
IFT54 intraflagellar transport 54
IFT57 intraflagellar transport 57
IFT70B intraflagellar transport 70B
IFT74 intraflagellar transport 74
IFT80 intraflagellar transport 80
IFT81 intraflagellar transport 81
IFT88 intraflagellar transport 88
IGF1R insulin-like growth factor 1 receptor
IL10RA interleukin 10 receptor, alpha
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
INTU inturned planar cell polarity protein
INVS inversin
IQCB1 IQ motif containing B1
IQCE IQ motif containing E
IQCG IQ motif containing G
IQUB IQ motif and ubiquitin domain containing
KATNIP katanin interacting protein
KIAA0753 KIAA0753
KIAA1671 KIAA1671
KIF17 kinesin family member 17
KIF19 kinesin family member 19
KIF27 kinesin family member 27
KIF3A kinesin family member 3A
KIF3B kinesin family member 3B
KIF3C kinesin family member 3C
KIF7 kinesin family member 7
KIFAP3 kinesin-associated protein 3
KISS1R KISS1 receptor
KLHL4 kelch-like family member 4
KMT5B lysine methyltransferase 5B
LCA5 Leber congenital amaurosis 5
LIPT2-AS1 LIPT2 antisense RNA 1
LPAR3 lysophosphatidic acid receptor 3
LZTFL1 leucine zipper transcription factor-like 1
MAP4 microtubule-associated protein 4
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPKAP1 mitogen-activated protein kinase associated protein 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MCHR1 melanin-concentrating hormone receptor 1
MCM7 minichromosome maintenance complex component 7
METAP2 methionyl aminopeptidase 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MICALL1 MICAL-like 1
MKKS McKusick-Kaufman syndrome
MLF1 myeloid leukemia factor 1
MNS1 meiosis-specific nuclear structural 1
MOK MOK protein kinase
MOSMO modulator of smoothened
MYOF myoferlin
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NECAB1 N-terminal EF-hand calcium binding protein 1
NEK1 NIMA-related kinase 1
NEK2 NIMA-related kinase 2
NEK5 NIMA-related kinase 5
NEK8 NIMA-related kinase 8
NME5 NME/NM23 family member 5
NME7 NME/NM23 family member 7
NOAZFP nucleolar atypical zinc finger
NPFFR1 neuropeptide FF receptor 1
NPHP1 nephronophthisis 1 (juvenile)
NPHP3 nephronophthisis 3 (adolescent)
NPHP4 nephronophthisis 4
NPY2R neuropeptide Y receptor Y2
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19
OCRL oculocerebrorenal syndrome of Lowe
ODAD1 outer dynein arm docking complex subunit 1
ODAD3 outer dynein arm docking complex subunit 3
ODF2 outer dense fiber of sperm tails 2
OFD1 oral-facial-digital syndrome 1
OXCT2 3-oxoacid CoA transferase 2
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCARE photoreceptor cilium actin regulator
PCM1 pericentriolar material 1
PDE4C phosphodiesterase 4C, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDIA6 protein disulfide isomerase family A, member 6
PDZD7 PDZ domain containing 7
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD1L1 polycystic kidney disease 1 like 1
PKD2L1 polycystic kidney disease 2-like 1
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PMEPA1 prostate transmembrane protein, androgen induced 1
PMM2 phosphomannomutase 2
PPID peptidylprolyl isomerase D
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PPP4R4 protein phosphatase 4, regulatory subunit 4
PQBP1 polyglutamine binding protein 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCI protein kinase C, iota
PRKD2 protein kinase D2
PRLHR prolactin releasing hormone receptor
PROM1 prominin 1
PROM2 prominin 2
PSKH1 protein serine kinase H1
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTCH1 patched 1
PTK2 protein tyrosine kinase 2
RAB10 RAB10, member RAS oncogene family
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB14 RAB14, member RAS oncogene family
RAB15 RAB15, member RAS oncogene family
RAB23 RAB23, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RHOD ras homolog family member D
RILPL1 Rab interacting lysosomal protein-like 1
RILPL2 Rab interacting lysosomal protein-like 2
RO60 Ro60, Y RNA binding protein
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROPN1 rhophilin associated tail protein 1
ROPN1B rhophilin associated tail protein 1B
ROPN1L rhophilin associated tail protein 1-like
RPAP2 RNA polymerase II associated protein 2
RPAP3 RNA polymerase II associated protein 3
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RPGRIP1L RPGRIP1-like
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae)
RSL1D1 ribosomal L1 domain containing 1
RSPH1 radial spoke head 1 homolog (Chlamydomonas)
RSPH10B radial spoke head 10 homolog B (Chlamydomonas)
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas)
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RSPH4A radial spoke head 4 homolog A (Chlamydomonas)
RSPH9 radial spoke head 9 homolog (Chlamydomonas)
S100B S100 calcium binding protein B
SAXO1 stabilizer of axonemal microtubules 1
SCAF1 SR-related CTD-associated factor 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SDCCAG8 serologically defined colon cancer antigen 8
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans)
SEPTIN2 septin 2
SEPTIN7 septin 7
SEPTIN9 septin 9
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SKA1 spindle and kinetochore associated complex subunit 1
SMAD6 SMAD family member 6
SMOX spermine oxidase
SNAP23 synaptosomal-associated protein, 23kDa
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SORD sorbitol dehydrogenase
SPA17 sperm autoantigenic protein 17
SPAG1 sperm associated antigen 1
SPAG8 sperm associated antigen 8
SPEF2 sperm flagellar 2
SPHK1 sphingosine kinase 1
SSTR3 somatostatin receptor 3
STING1 stimulator of interferon response cGAMP interactor 1
STK11 serine/threonine kinase 11
SUFU suppressor of fused homolog (Drosophila)
SYNE2 spectrin repeat containing, nuclear envelope 2
TAS2R43 taste receptor, type 2, member 43
TBC1D30 TBC1 domain family, member 30
TCHP trichoplein, keratin filament binding
TCTN2 tectonic family member 2
TCTN3 tectonic family member 3
TEDC1 tubulin epsilon and delta complex 1
TEDC2 tubulin epsilon and delta complex 2
TGFBR1 transforming growth factor, beta receptor 1
TMEM138 transmembrane protein 138
TMEM17 transmembrane protein 17
TMEM216 transmembrane protein 216
TMEM231 transmembrane protein 231
TMEM237 transmembrane protein 237
TMEM67 transmembrane protein 67
TNPO1 transportin 1
TOGARAM1 TOG array regulator of axonemal microtubules 1
TOGARAM2 TOG array regulator of axonemal microtubules 2
TRIP11 thyroid hormone receptor interactor 11
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSGA10 testis specific, 10
TSSK1B testis-specific serine kinase 1B
TTBK2 tau tubulin kinase 2
TTC21B tetratricopeptide repeat domain 21B
TTC23 tetratricopeptide repeat domain 23
TTC26 tetratricopeptide repeat domain 26
TTC8 tetratricopeptide repeat domain 8
TTLL3 tubulin tyrosine ligase-like family member 3
TTLL6 tubulin tyrosine ligase-like family member 6
TTLL8 tubulin tyrosine ligase-like family member 8
TUB tubby bipartite transcription factor
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TUBA3E tubulin, alpha 3e
TUBA4A tubulin, alpha 4a
TUBGCP5 tubulin, gamma complex associated protein 5
TULP1 tubby like protein 1
TULP2 tubby like protein 2
TULP3 tubby like protein 3
TXNDC15 thioredoxin domain containing 15
UBXN10 UBX domain protein 10
UMOD uromodulin
UNC119B unc-119 homolog B (C. elegans)
USH1C Usher syndrome 1C (autosomal recessive, severe)
USP9X ubiquitin specific peptidase 9, X-linked
UTRN utrophin
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WDPCP WD repeat containing planar cell polarity effector
WDR11 WD repeat domain 11
WDR19 WD repeat domain 19
WDR35 WD repeat domain 35
WDR54 WD repeat domain 54
WHRN whirlin