| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the cimetidine-1464 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ACTN4 | actinin, alpha 4 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APP | amyloid beta (A4) precursor protein |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARTN | artemin |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CD200 | CD200 molecule |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEP152 | centrosomal protein 152kDa |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CREBZF | CREB/ATF bZIP transcription factor |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DMPK | dystrophia myotonica-protein kinase |
| ESR1 | estrogen receptor 1 |
| FAM46C | family with sequence similarity 46, member C |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FLOT1 | flotillin 1 |
| GOSR1 | golgi SNAP receptor complex member 1 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPATCH3 | G patch domain containing 3 |
| GPR137 | G protein-coupled receptor 137 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| GSPT1 | G1 to S phase transition 1 |
| HDAC11 | histone deacetylase 11 |
| HHEX | hematopoietically expressed homeobox |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 |
| HOXC10 | homeobox C10 |
| HPX | hemopexin |
| IGSF1 | immunoglobulin superfamily, member 1 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KDM6A | lysine (K)-specific demethylase 6A |
| LAMB2 | laminin, beta 2 (laminin S) |
| LMAN1 | lectin, mannose-binding, 1 |
| LRRC61 | leucine rich repeat containing 61 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MBD1 | methyl-CpG binding domain protein 1 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| METTL5 | methyltransferase like 5 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MST1 | macrophage stimulating 1 |
| MTMR1 | myotubularin related protein 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NGLY1 | N-glycanase 1 |
| NME5 | NME/NM23 family member 5 |
| NNT | nicotinamide nucleotide transhydrogenase |
| NOAZFP | nucleolar atypical zinc finger |
| PAX5 | paired box 5 |
| PCM1 | pericentriolar material 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PORCN | porcupine homolog (Drosophila) |
| PPAT | phosphoribosyl pyrophosphate amidotransferase |
| PRKD3 | protein kinase D3 |
| PRNP | prion protein |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| RPS9 | ribosomal protein S9 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SENP5 | SUMO1/sentrin specific peptidase 5 |
| SIK3 | SIK family kinase 3 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SLC17A2 | solute carrier family 17, member 2 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STK10 | serine/threonine kinase 10 |
| STK17B | serine/threonine kinase 17b |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TBX5 | T-box 5 |
| TMOD1 | tropomodulin 1 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 |
| USP34 | ubiquitin specific peptidase 34 |
| VN1R1 | vomeronasal 1 receptor 1 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| XYLT1 | xylosyltransferase I |
| ZNF134 | zinc finger protein 134 |
| ZNF362 | zinc finger protein 362 |
| ZNF609 | zinc finger protein 609 |
| ZW10 | zw10 kinetochore protein |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B9D2 | B9 protein domain 2 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CAPN5 | calpain 5 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CENPO | centromere protein O |
| CHKB | choline kinase beta |
| CIDEC | cell death-inducing DFFA-like effector c |
| CST6 | cystatin E/M |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP8 | dual specificity phosphatase 8 |
| EPPK1 | epiplakin 1 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FADS2 | fatty acid desaturase 2 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIRA | histone cell cycle regulator |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2AM | histone cluster 1, H2am |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| INADL | InaD-like (Drosophila) |
| IRF1 | interferon regulatory factor 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLHL25 | kelch-like family member 25 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MON1B | MON1 secretory trafficking family member B |
| NOTCH1 | notch 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCBP4 | poly(rC) binding protein 4 |
| PCDHA9 | protocadherin alpha 9 |
| PCDHB13 | protocadherin beta 13 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLA2G3 | phospholipase A2, group III |
| PRR4 | proline rich 4 (lacrimal) |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RHBDD3 | rhomboid domain containing 3 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF39 | ring finger protein 39 |
| SH2D4A | SH2 domain containing 4A |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TCTA | T-cell leukemia translocation altered |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TSC22D4 | TSC22 domain family, member 4 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USP36 | ubiquitin specific peptidase 36 |
| VASH2 | vasohibin 2 |
| VEGFB | vascular endothelial growth factor B |
| VPS9D1 | VPS9 domain containing 1 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF350 | zinc finger protein 350 |
| ZNF423 | zinc finger protein 423 |
| ZNF428 | zinc finger protein 428 |
| ZNF442 | zinc finger protein 442 |
| ZNF573 | zinc finger protein 573 |
| ZNF747 | zinc finger protein 747 |
| ZNF816 | zinc finger protein 816 |
