| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the cimetidine-1884 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AIM1L | absent in melanoma 1-like |
| ALAD | aminolevulinate dehydratase |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APOE | apolipoprotein E |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACFD1 | calcium channel flower domain containing 1 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CACNA1S | calcium channel, voltage-dependent, L type, alpha 1S subunit |
| CALB2 | calbindin 2 |
| CAMKV | CaM kinase-like vesicle-associated |
| CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 |
| CHN2 | chimerin 2 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLTA | clathrin, light chain A |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNTFR | ciliary neurotrophic factor receptor |
| CORT | cortistatin |
| CPM | carboxypeptidase M |
| CPNE7 | copine VII |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DAZAP1 | DAZ associated protein 1 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DUSP26 | dual specificity phosphatase 26 (putative) |
| EIF1 | eukaryotic translation initiation factor 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLJ42627 | uncharacterized LOC645644 |
| FSCN1 | fascin actin-bundling protein 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAL | galanin/GMAP prepropeptide |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IL2RG | interleukin 2 receptor, gamma |
| IQCC | IQ motif containing C |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIF1C | kinesin family member 1C |
| KIF25 | kinesin family member 25 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LAMA2 | laminin, alpha 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| METTL7A | methyltransferase like 7A |
| MIIP | migration and invasion inhibitory protein |
| MRC2 | mannose receptor, C type 2 |
| MTF1 | metal-regulatory transcription factor 1 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYT1 | myelin transcription factor 1 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NIPAL2 | NIPA-like domain containing 2 |
| NPEPL1 | aminopeptidase-like 1 |
| NPPA | natriuretic peptide A |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLCG1 | phospholipase C, gamma 1 |
| PLD2 | phospholipase D2 |
| PNMT | phenylethanolamine N-methyltransferase |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRLH | prolactin releasing hormone |
| PTGES2 | prostaglandin E synthase 2 |
| RAB2A | RAB2A, member RAS oncogene family |
| RANBP3 | RAN binding protein 3 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RPL7 | ribosomal protein L7 |
| RRAD | Ras-related associated with diabetes |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCN5A | sodium channel, voltage gated, type V alpha subunit |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SFTPC | surfactant protein C |
| SH2B1 | SH2B adaptor protein 1 |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) |
| SPN | sialophorin |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| TRIM29 | tripartite motif containing 29 |
| TUBA4B | tubulin, alpha 4b |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBQLN4 | ubiquilin 4 |
| UBTD1 | ubiquitin domain containing 1 |
| UNC45A | unc-45 homolog A (C. elegans) |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VGF | VGF nerve growth factor inducible |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZFHX2 | zinc finger homeobox 2 |
| Symbol | Name |
|---|---|
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ARHGAP17 | Rho GTPase activating protein 17 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| BCL7C | B-cell CLL/lymphoma 7C |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C1ORF27 | chromosome 1 open reading frame 27 |
| CAPNS1 | calpain, small subunit 1 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) |
| CDA | cytidine deaminase |
| CDCA8 | cell division cycle associated 8 |
| CEP85 | centrosomal protein 85kDa |
| CFD | complement factor D (adipsin) |
| CLK2 | CDC-like kinase 2 |
| COMMD9 | COMM domain containing 9 |
| DAP | death-associated protein |
| ECH1 | enoyl CoA hydratase 1, peroxisomal |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EMC9 | ER membrane protein complex subunit 9 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERCC2 | excision repair cross-complementation group 2 |
| FKBPL | FK506 binding protein like |
| FUCA1 | fucosidase, alpha-L- 1, tissue |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GALR3 | galanin receptor 3 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GLOD4 | glyoxalase domain containing 4 |
| GOLGA3 | golgin A3 |
| GOLPH3L | golgi phosphoprotein 3-like |
| GPS2 | G protein pathway suppressor 2 |
| HARS | histidyl-tRNA synthetase |
| HIST1H2BF | histone cluster 1, H2bf |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 |
| JMJD4 | jumonji domain containing 4 |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KIF1B | kinesin family member 1B |
| KRT34 | keratin 34, type I |
| LIG1 | ligase I, DNA, ATP-dependent |
| LSR | lipolysis stimulated lipoprotein receptor |
| LY6E | lymphocyte antigen 6 complex, locus E |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MGMT | O-6-methylguanine-DNA methyltransferase |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MRPL16 | mitochondrial ribosomal protein L16 |
| MSRB1 | methionine sulfoxide reductase B1 |
| MT1HL1 | metallothionein 1H-like 1 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
| NCAPH | non-SMC condensin I complex, subunit H |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NVL | nuclear VCP-like |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OGFRL1 | opioid growth factor receptor-like 1 |
| ORC3 | origin recognition complex, subunit 3 |
| P3H2 | prolyl 3-hydroxylase 2 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PCTP | phosphatidylcholine transfer protein |
| PKN1 | protein kinase N1 |
| PLTP | phospholipid transfer protein |
| POGK | pogo transposable element with KRAB domain |
| POR | P450 (cytochrome) oxidoreductase |
| POU2F1 | POU class 2 homeobox 1 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PYGB | phosphorylase, glycogen; brain |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM10 | RNA binding motif protein 10 |
| RECQL4 | RecQ protein-like 4 |
| RNF220 | ring finger protein 220 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SCNM1 | sodium channel modifier 1 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SMYD5 | SMYD family member 5 |
| SNF8 | SNF8, ESCRT-II complex subunit |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM51 | transmembrane protein 51 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIM58 | tripartite motif containing 58 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTC23 | tetratricopeptide repeat domain 23 |
| UGDH | UDP-glucose 6-dehydrogenase |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VPS52 | vacuolar protein sorting 52 homolog (S. cerevisiae) |
| WDR6 | WD repeat domain 6 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF532 | zinc finger protein 532 |