| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the cimetidine-4063 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX3 | acyl-CoA oxidase 3, pristanoyl |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| ADGB | androglobin |
| ADGRB3 | adhesion G protein-coupled receptor B3 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATF7 | activating transcription factor 7 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C2CD2L | C2CD2-like |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CCND2 | cyclin D2 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN16 | claudin 16 |
| CLUL1 | clusterin-like 1 (retinal) |
| CNTN5 | contactin 5 |
| COL3A1 | collagen, type III, alpha 1 |
| COL9A3 | collagen, type IX, alpha 3 |
| COMMD4 | COMM domain containing 4 |
| CTSS | cathepsin S |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EPHB1 | EPH receptor B1 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GLP1R | glucagon-like peptide 1 receptor |
| GNRHR | gonadotropin-releasing hormone receptor |
| GRIP2 | glutamate receptor interacting protein 2 |
| HIF3A | hypoxia inducible factor 3, alpha subunit |
| HOXD13 | homeobox D13 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| ING4 | inhibitor of growth family, member 4 |
| INSR | insulin receptor |
| KALRN | kalirin, RhoGEF kinase |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIF1C | kinesin family member 1C |
| KLK1 | kallikrein 1 |
| LILRA5 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAPK8 | mitogen-activated protein kinase 8 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MEP1B | meprin A, beta |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MST1L | macrophage stimulating 1-like |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 |
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 |
| OGG1 | 8-oxoguanine DNA glycosylase |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PDE7B | phosphodiesterase 7B |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PDX1 | pancreatic and duodenal homeobox 1 |
| PHF8 | PHD finger protein 8 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLK4 | polo-like kinase 4 |
| POU5F1P3 | POU class 5 homeobox 1 pseudogene 3 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PRDM14 | PR domain containing 14 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTAFR | platelet-activating factor receptor |
| PTCRA | pre T-cell antigen receptor alpha |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RAP1GAP | RAP1 GTPase activating protein |
| REN | renin |
| RIF1 | replication timing regulatory factor 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPH3A | rabphilin 3A |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SCN4A | sodium channel, voltage gated, type IV alpha subunit |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC25A30 | solute carrier family 25, member 30 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SNX13 | sorting nexin 13 |
| SPAG6 | sperm associated antigen 6 |
| SPATA1 | spermatogenesis associated 1 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| SYT5 | synaptotagmin V |
| TAOK2 | TAO kinase 2 |
| TBXA2R | thromboxane A2 receptor |
| TCF3 | transcription factor 3 |
| TTC30A | tetratricopeptide repeat domain 30A |
| ULBP1 | UL16 binding protein 1 |
| USP53 | ubiquitin specific peptidase 53 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZNF573 | zinc finger protein 573 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD36 | ankyrin repeat domain 36 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1RL | complement component 1, r subcomponent-like |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CLCA1 | chloride channel accessory 1 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRMP1 | collapsin response mediator protein 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYB5R2 | cytochrome b5 reductase 2 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DFNB31 | deafness, autosomal recessive 31 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DPYS | dihydropyrimidinase |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM53B | family with sequence similarity 53, member B |
| FBXO22 | F-box protein 22 |
| FBXO31 | F-box protein 31 |
| FGL1 | fibrinogen-like 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GAN | gigaxonin |
| GPC3 | glypican 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H3A | histone cluster 1, H3a |
| HIST1H4C | histone cluster 1, H4c |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXA2 | homeobox A2 |
| HOXC5 | homeobox C5 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFT140 | intraflagellar transport 140 |
| INO80D | INO80 complex subunit D |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIF13B | kinesin family member 13B |
| KRT86 | keratin 86, type II |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MYBBP1A | MYB binding protein (P160) 1a |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NGF | nerve growth factor (beta polypeptide) |
| NINJ1 | ninjurin 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRR14L | proline rich 14-like |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SDC3 | syndecan 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SSTR4 | somatostatin receptor 4 |
| STEAP4 | STEAP family member 4 |
| TAOK1 | TAO kinase 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TUBA3C | tubulin, alpha 3c |
| UGT8 | UDP glycosyltransferase 8 |
| VASP | vasodilator-stimulated phosphoprotein |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VGF | VGF nerve growth factor inducible |
| WDR25 | WD repeat domain 25 |
| WDR62 | WD repeat domain 62 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF415 | zinc finger protein 415 |
| ZNF669 | zinc finger protein 669 |
| ZNF747 | zinc finger protein 747 |
| ZNF749 | zinc finger protein 749 |
| ZNF76 | zinc finger protein 76 |
| ZNF768 | zinc finger protein 768 |
| ZNF816 | zinc finger protein 816 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |