| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the cimetidine-4144 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AIM2 | absent in melanoma 2 |
| APOE | apolipoprotein E |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BMP6 | bone morphogenetic protein 6 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCL8 | chemokine (C-C motif) ligand 8 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CFDP1 | craniofacial development protein 1 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CTF1 | cardiotrophin 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DCTN2 | dynactin 2 (p50) |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DENND3 | DENN/MADD domain containing 3 |
| DENND5B | DENN/MADD domain containing 5B |
| DOK4 | docking protein 4 |
| EDNRA | endothelin receptor type A |
| FSCN1 | fascin actin-bundling protein 1 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| GPR85 | G protein-coupled receptor 85 |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIST1H1T | histone cluster 1, H1t |
| HOPX | HOP homeobox |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGL | immunoglobulin lambda locus |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGB8 | integrin, beta 8 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| LAMC2 | laminin, gamma 2 |
| LBP | lipopolysaccharide binding protein |
| LEPR | leptin receptor |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MED18 | mediator complex subunit 18 |
| MMP27 | matrix metallopeptidase 27 |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| NME5 | NME/NM23 family member 5 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PCDH7 | protocadherin 7 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POU3F2 | POU class 3 homeobox 2 |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| R3HDM1 | R3H domain containing 1 |
| RAB6B | RAB6B, member RAS oncogene family |
| RPL35A | ribosomal protein L35a |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SH2D2A | SH2 domain containing 2A |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC35G2 | solute carrier family 35, member G2 |
| SOCS7 | suppressor of cytokine signaling 7 |
| SOX30 | SRY (sex determining region Y)-box 30 |
| SP100 | SP100 nuclear antigen |
| SP110 | SP110 nuclear body protein |
| SRCAP | Snf2-related CREBBP activator protein |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| SYNJ2 | synaptojanin 2 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TDRD12 | tudor domain containing 12 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TNS1 | tensin 1 |
| TPMT | thiopurine S-methyltransferase |
| TUBA3C | tubulin, alpha 3c |
| UNC5B | unc-5 homolog B (C. elegans) |
| VCL | vinculin |
| XYLB | xylulokinase homolog (H. influenzae) |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABHD17B | abhydrolase domain containing 17B |
| ADCK4 | aarF domain containing kinase 4 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALS2CL | ALS2 C-terminal like |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARMC4 | armadillo repeat containing 4 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| BCO1 | beta-carotene oxygenase 1 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CCDC71 | coiled-coil domain containing 71 |
| CCNO | cyclin O |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLEC4E | C-type lectin domain family 4, member E |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CPB1 | carboxypeptidase B1 (tissue) |
| CPB2 | carboxypeptidase B2 (plasma) |
| CSF1R | colony stimulating factor 1 receptor |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DOK5 | docking protein 5 |
| DSPP | dentin sialophosphoprotein |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| F9 | coagulation factor IX |
| FAM131A | family with sequence similarity 131, member A |
| FBXO2 | F-box protein 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FOXI1 | forkhead box I1 |
| GFI1 | growth factor independent 1 transcription repressor |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HDAC11 | histone deacetylase 11 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H3F | histone cluster 1, H3f |
| HMOX1 | heme oxygenase 1 |
| IFT140 | intraflagellar transport 140 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL2 | interleukin 2 |
| INO80D | INO80 complex subunit D |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KRT83 | keratin 83, type II |
| MED31 | mediator complex subunit 31 |
| METTL16 | methyltransferase like 16 |
| MOB3B | MOB kinase activator 3B |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTCP1 | mature T-cell proliferation 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OCA2 | oculocutaneous albinism II |
| OSMR | oncostatin M receptor |
| PDE12 | phosphodiesterase 12 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLCD1 | phospholipase C, delta 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RFPL3 | ret finger protein-like 3 |
| RND1 | Rho family GTPase 1 |
| S100A9 | S100 calcium binding protein A9 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMIM14 | small integral membrane protein 14 |
| TBC1D19 | TBC1 domain family, member 19 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TOR4A | torsin family 4, member A |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TSGA10 | testis specific, 10 |
| TYRP1 | tyrosinase-related protein 1 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| ULBP2 | UL16 binding protein 2 |
| VN1R1 | vomeronasal 1 receptor 1 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF428 | zinc finger protein 428 |
| ZNF551 | zinc finger protein 551 |
