cinchocaine-1469 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the cinchocaine-1469 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADTRP androgen-dependent TFPI-regulating protein
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
BEX1 brain expressed, X-linked 1
BHMT2 betaine--homocysteine S-methyltransferase 2
C2ORF27A chromosome 2 open reading frame 27A
C3 complement component 3
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDC42 cell division cycle 42
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLPS colipase, pancreatic
DCAKD dephospho-CoA kinase domain containing
EFNA5 ephrin-A5
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
EPHA5 EPH receptor A5
EPHB2 EPH receptor B2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ESR1 estrogen receptor 1
FAM214B family with sequence similarity 214, member B
FBXL7 F-box and leucine-rich repeat protein 7
FGFR1 fibroblast growth factor receptor 1
FLT3 fms-related tyrosine kinase 3
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GK glycerol kinase
GLE1 GLE1 RNA export mediator
GMPR guanosine monophosphate reductase
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPATCH3 G patch domain containing 3
GPR25 G protein-coupled receptor 25
GPRC5D G protein-coupled receptor, class C, group 5, member D
HFE hemochromatosis
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1A interleukin 1, alpha
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
LAX1 lymphocyte transmembrane adaptor 1
LDB3 LIM domain binding 3
LGALS9 lectin, galactoside-binding, soluble, 9
LHX1 LIM homeobox 1
LRP6 low density lipoprotein receptor-related protein 6
MAN2A2 mannosidase, alpha, class 2A, member 2
MFN2 mitofusin 2
MMP25 matrix metallopeptidase 25
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO7A myosin VIIA
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRSN2 neurensin 2
NUMA1 nuclear mitotic apparatus protein 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARVA parvin, alpha
PDE4DIP phosphodiesterase 4D interacting protein
POU2F2 POU class 2 homeobox 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTCRA pre T-cell antigen receptor alpha
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRO protein tyrosine phosphatase, receptor type, O
PTPRS protein tyrosine phosphatase, receptor type, S
PYHIN1 pyrin and HIN domain family, member 1
RAB11B RAB11B, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
REM1 RAS (RAD and GEM)-like GTP-binding 1
RPL10L ribosomal protein L10-like
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS14 ribosomal protein S14
S100A13 S100 calcium binding protein A13
SAMD4A sterile alpha motif domain containing 4A
SCAND2P SCAN domain containing 2 pseudogene
SH2D2A SH2 domain containing 2A
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC17A4 solute carrier family 17, member 4
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SPDEF SAM pointed domain containing ETS transcription factor
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STAG3 stromal antigen 3
SVIL supervillin
SYMPK symplekin
TAOK1 TAO kinase 1
TAPBP TAP binding protein (tapasin)
TCHH trichohyalin
TGM2 transglutaminase 2
TJAP1 tight junction associated protein 1 (peripheral)
TMC7 transmembrane channel-like 7
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAPPC9 trafficking protein particle complex 9
TUBA3C tubulin, alpha 3c
TYRP1 tyrosinase-related protein 1
WDR55 WD repeat domain 55
WDR78 WD repeat domain 78
ZNF117 zinc finger protein 117
ZNF180 zinc finger protein 180
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
AACS acetoacetyl-CoA synthetase
ABHD14A abhydrolase domain containing 14A
ABLIM3 actin binding LIM protein family, member 3
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACVR2B activin A receptor, type IIB
AFF4 AF4/FMR2 family, member 4
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APOD apolipoprotein D
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARRB1 arrestin, beta 1
ATG4A autophagy related 4A, cysteine peptidase
BAHD1 bromo adjacent homology domain containing 1
C1ORF105 chromosome 1 open reading frame 105
C1ORF106 chromosome 1 open reading frame 106
C2ORF44 chromosome 2 open reading frame 44
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CCNO cyclin O
CINP cyclin-dependent kinase 2 interacting protein
CSTA cystatin A (stefin A)
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CXORF56 chromosome X open reading frame 56
DENND1A DENN/MADD domain containing 1A
DESI1 desumoylating isopeptidase 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DUSP2 dual specificity phosphatase 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ERCC4 excision repair cross-complementation group 4
FBXO22 F-box protein 22
FBXO46 F-box protein 46
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBP2 FK506 binding protein 2, 13kDa
FKBP5 FK506 binding protein 5
GDAP1 ganglioside induced differentiation associated protein 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPALPP1 GPALPP motifs containing 1
GRTP1 growth hormone regulated TBC protein 1
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HCFC2 host cell factor C2
HIRA histone cell cycle regulator
HOXC11 homeobox C11
IGFBP6 insulin-like growth factor binding protein 6
IL22 interleukin 22
ITPKB inositol-trisphosphate 3-kinase B
KLHL36 kelch-like family member 36
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LINC00339 long intergenic non-protein coding RNA 339
MRPL52 mitochondrial ribosomal protein L52
NOD1 nucleotide-binding oligomerization domain containing 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUP62CL nucleoporin 62kDa C-terminal like
ORAI3 ORAI calcium release-activated calcium modulator 3
OSMR oncostatin M receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDHA6 protocadherin alpha 6
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIBF1 progesterone immunomodulatory binding factor 1
PLAC8 placenta-specific 8
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLIN3 perilipin 3
PMCH pro-melanin-concentrating hormone
PRMT7 protein arginine methyltransferase 7
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
RNF111 ring finger protein 111
RNF25 ring finger protein 25
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPS21 ribosomal protein S21
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RWDD2A RWD domain containing 2A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIX1 SIX homeobox 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLMO1 slowmo homolog 1 (Drosophila)
SMG9 SMG9 nonsense mediated mRNA decay factor
SP140L SP140 nuclear body protein-like
SPIDR scaffolding protein involved in DNA repair
SRSF4 serine/arginine-rich splicing factor 4
STARD3 StAR-related lipid transfer (START) domain containing 3
SYNJ2BP synaptojanin 2 binding protein
SYTL2 synaptotagmin-like 2
TCTN2 tectonic family member 2
THRAP3 thyroid hormone receptor associated protein 3
TLN1 talin 1
TRAIP TRAF interacting protein
TSLIG2 tRNA splicing ligase complex subunit 2
USP36 ubiquitin specific peptidase 36
VEGFB vascular endothelial growth factor B
VPS9D1 VPS9 domain containing 1
WFDC2 WAP four-disulfide core domain 2
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350
ZNF442 zinc finger protein 442
ZNF767P zinc finger family member 767, pseudogene
ZSCAN31 zinc finger and SCAN domain containing 31