cinchocaine-1969 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cinchocaine-1969 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACAA2 acetyl-CoA acyltransferase 2
ACTC1 actin, alpha, cardiac muscle 1
ADM2 adrenomedullin 2
AKAP13 A kinase (PRKA) anchor protein 13
ALDOB aldolase B, fructose-bisphosphate
APAF1 apoptotic peptidase activating factor 1
ARHGAP32 Rho GTPase activating protein 32
ARL1 ADP-ribosylation factor-like 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
AVL9 AVL9 homolog (S. cerevisiase)
BCL6 B-cell CLL/lymphoma 6
BCOR BCL6 corepressor
BMP2K BMP2 inducible kinase
BSDC1 BSD domain containing 1
C16ORF58 chromosome 16 open reading frame 58
CALHM2 calcium homeostasis modulator 2
CBX6 chromobox homolog 6
CDK17 cyclin-dependent kinase 17
CEL carboxyl ester lipase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHD9 chromodomain helicase DNA binding protein 9
CPTP ceramide-1-phosphate transfer protein
CSF1R colony stimulating factor 1 receptor
CYLD cylindromatosis (turban tumor syndrome)
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DTNA dystrobrevin, alpha
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EHD1 EH-domain containing 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM134B family with sequence similarity 134, member B
FPR2 formyl peptide receptor 2
FURIN furin (paired basic amino acid cleaving enzyme)
FYB FYN binding protein
GALR3 galanin receptor 3
GSDMD gasdermin D
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
HDAC5 histone deacetylase 5
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H1E histone cluster 1, H1e
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IFI16 interferon, gamma-inducible protein 16
IFT122 intraflagellar transport 122
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL13RA1 interleukin 13 receptor, alpha 1
IL1R2 interleukin 1 receptor, type II
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIF2A kinesin heavy chain member 2A
KIFC1 kinesin family member C1
KLF6 Kruppel-like factor 6
KLHL18 kelch-like family member 18
KLK1 kallikrein 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LMNA lamin A/C
LOC399491
LPCAT1 lysophosphatidylcholine acyltransferase 1
LRRC42 leucine rich repeat containing 42
MPDU1 mannose-P-dolichol utilization defect 1
MTMR2 myotubularin related protein 2
MVK mevalonate kinase
NRIP3 nuclear receptor interacting protein 3
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
PAM peptidylglycine alpha-amidating monooxygenase
PARP16 poly (ADP-ribose) polymerase family, member 16
PEX13 peroxisomal biogenesis factor 13
PIAS4 protein inhibitor of activated STAT, 4
PILRB paired immunoglobin-like type 2 receptor beta
PKNOX1 PBX/knotted 1 homeobox 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POR P450 (cytochrome) oxidoreductase
PRRC2C proline-rich coiled-coil 2C
PTPRA protein tyrosine phosphatase, receptor type, A
RAD54L2 RAD54-like 2 (S. cerevisiae)
RGS1 regulator of G-protein signaling 1
RHOH ras homolog family member H
SH2D3A SH2 domain containing 3A
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SMAD6 SMAD family member 6
SND1-IT1 SND1 intronic transcript 1
SUGP1 SURP and G patch domain containing 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYMPK symplekin
TDRD3 tudor domain containing 3
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRD T cell receptor delta locus
TRMT61A tRNA methyltransferase 61A
TXNL4A thioredoxin-like 4A
U2AF2 U2 small nuclear RNA auxiliary factor 2
WDR13 WD repeat domain 13
WDR44 WD repeat domain 44
ZFYVE9 zinc finger, FYVE domain containing 9
ZHX2 zinc fingers and homeoboxes 2
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF451 zinc finger protein 451
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABHD11 abhydrolase domain containing 11
ACYP2 acylphosphatase 2, muscle type
ALPK1 alpha-kinase 1
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARMCX5 armadillo repeat containing, X-linked 5
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
BCORL1 BCL6 corepressor-like 1
BTNL3 butyrophilin-like 3
C16ORF62 chromosome 16 open reading frame 62
C1ORF35 chromosome 1 open reading frame 35
C9ORF40 chromosome 9 open reading frame 40
CD38 CD38 molecule
CEND1 cell cycle exit and neuronal differentiation 1
CEP72 centrosomal protein 72kDa
CFL1 cofilin 1 (non-muscle)
CHMP1A charged multivesicular body protein 1A
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CINP cyclin-dependent kinase 2 interacting protein
CISH cytokine inducible SH2-containing protein
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COQ4 coenzyme Q4
CRIPT cysteine-rich PDZ-binding protein
CRY1 cryptochrome circadian clock 1
CTSH cathepsin H
DCTN4 dynactin 4 (p62)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DPH2 DPH2 homolog (S. cerevisiae)
EGLN2 egl-9 family hypoxia-inducible factor 2
ELP5 elongator acetyltransferase complex subunit 5
FAM179B family with sequence similarity 179, member B
FAM193B family with sequence similarity 193, member B
FAM206A family with sequence similarity 206, member A
FAM53C family with sequence similarity 53, member C
FAM63A family with sequence similarity 63, member A
FBXO46 F-box protein 46
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GPR27 G protein-coupled receptor 27
GSR glutathione reductase
HIST1H1C histone cluster 1, H1c
INTS9 integrator complex subunit 9
ITGA10 integrin, alpha 10
KCTD20 potassium channel tetramerization domain containing 20
LIMA1 LIM domain and actin binding 1
LIMD2 LIM domain containing 2
LMNB2 lamin B2
LSP1 lymphocyte-specific protein 1
MFSD12 major facilitator superfamily domain containing 12
MLPH melanophilin
MOCS2 molybdenum cofactor synthesis 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MYL12B myosin, light chain 12B, regulatory
MYO1C myosin IC
NINJ1 ninjurin 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PADI1 peptidyl arginine deiminase, type I
PAQR3 progestin and adipoQ receptor family member III
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PNRC1 proline-rich nuclear receptor coactivator 1
PSKH1 protein serine kinase H1
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB4B RAB4B, member RAS oncogene family
RAD9A RAD9 homolog A (S. pombe)
RIC8A RIC8 guanine nucleotide exchange factor A
RIN1 Ras and Rab interactor 1
RNF122 ring finger protein 122
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SDHAF3 succinate dehydrogenase complex assembly factor 3
SECISBP2 SECIS binding protein 2
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SETD1B SET domain containing 1B
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STAU2 staufen double-stranded RNA binding protein 2
STYXL1 serine/threonine/tyrosine interacting-like 1
TAC3 tachykinin 3
TCTN2 tectonic family member 2
TERT telomerase reverse transcriptase
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM38B transmembrane protein 38B
TPX2 TPX2, microtubule-associated
TRMT61B tRNA methyltransferase 61B
TWIST1 twist family bHLH transcription factor 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UNC93B1 unc-93 homolog B1 (C. elegans)
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
USB1 U6 snRNA biogenesis 1
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
ZDHHC13 zinc finger, DHHC-type containing 13
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF16 zinc finger protein 16
ZNF669 zinc finger protein 669
ZNF671 zinc finger protein 671
ZNF85 zinc finger protein 85
ZXDC ZXD family zinc finger C