cinchocaine-4068 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the cinchocaine-4068 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKR1C4 aldo-keto reductase family 1, member C4
ARHGAP26 Rho GTPase activating protein 26
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BEGAIN brain-enriched guanylate kinase-associated
BGN biglycan
BTN3A1 butyrophilin, subfamily 3, member A1
BTNL3 butyrophilin-like 3
C5AR2 complement component 5a receptor 2
CACFD1 calcium channel flower domain containing 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CHD5 chromodomain helicase DNA binding protein 5
CLCA2 chloride channel accessory 2
CLCN4 chloride channel, voltage-sensitive 4
CLEC11A C-type lectin domain family 11, member A
CLEC3B C-type lectin domain family 3, member B
CLEC4M C-type lectin domain family 4, member M
CLTA clathrin, light chain A
DCAF15 DDB1 and CUL4 associated factor 15
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPO erythropoietin
EPS8L3 EPS8-like 3
ESR1 estrogen receptor 1
EVI2A ecotropic viral integration site 2A
FAS Fas cell surface death receptor
FCAR Fc fragment of IgA receptor
FER1L4 fer-1-like family member 4, pseudogene (functional)
GJA8 gap junction protein, alpha 8, 50kDa
GLRA1 glycine receptor, alpha 1
GRIA3 glutamate receptor, ionotropic, AMPA 3
HAL histidine ammonia-lyase
HAVCR1 hepatitis A virus cellular receptor 1
HLA-DOA major histocompatibility complex, class II, DO alpha
HRASLS2 HRAS-like suppressor 2
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL10 interleukin 10
INO80B INO80 complex subunit B
KALRN kalirin, RhoGEF kinase
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIPG lipase, endothelial
LOC100287590 uncharacterized LOC100287590
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MAG myelin associated glycoprotein
MC3R melanocortin 3 receptor
MCF2 MCF.2 cell line derived transforming sequence
MVD mevalonate (diphospho) decarboxylase
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NFASC neurofascin
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRXN2 neurexin 2
OMD osteomodulin
PADI4 peptidyl arginine deiminase, type IV
PCDHA9 protocadherin alpha 9
PDE4DIP phosphodiesterase 4D interacting protein
PGLYRP1 peptidoglycan recognition protein 1
PHF3 PHD finger protein 3
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLK4 polo-like kinase 4
PNLIPRP2 pancreatic lipase-related protein 2
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRAMEF10 PRAME family member 10
RNF126P1 ring finger protein 126 pseudogene 1
RYR1 ryanodine receptor 1 (skeletal)
SARM1 sterile alpha and TIR motif containing 1
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SORBS1 sorbin and SH3 domain containing 1
SPON1 spondin 1, extracellular matrix protein
SUGP1 SURP and G patch domain containing 1
SULT4A1 sulfotransferase family 4A, member 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TLR1 toll-like receptor 1
TPM2 tropomyosin 2 (beta)
TRIM15 tripartite motif containing 15
TRIM48 tripartite motif containing 48
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TTC12 tetratricopeptide repeat domain 12
ULBP1 UL16 binding protein 1
UNC13A unc-13 homolog A (C. elegans)
VRTN vertebrae development associated
XAF1 XIAP associated factor 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
AKTIP AKT interacting protein
ALS2CL ALS2 C-terminal like
AOC2 amine oxidase, copper containing 2 (retina-specific)
ATP10D ATPase, class V, type 10D
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAG4 BCL2-associated athanogene 4
BAHCC1 BAH domain and coiled-coil containing 1
BFSP1 beaded filament structural protein 1, filensin
BHLHE41 basic helix-loop-helix family, member e41
C4ORF29 chromosome 4 open reading frame 29
CA5BP1 carbonic anhydrase VB pseudogene 1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDKL3 cyclin-dependent kinase-like 3
CENPJ centromere protein J
CLGN calmegin
CTSO cathepsin O
DENND4A DENN/MADD domain containing 4A
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EFNA3 ephrin-A3
EIF5A2 eukaryotic translation initiation factor 5A2
FAM86C1 family with sequence similarity 86, member C1
FBXL6 F-box and leucine-rich repeat protein 6
FPGS folylpolyglutamate synthase
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GDAP1 ganglioside induced differentiation associated protein 1
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR3 G protein-coupled receptor 3
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HDAC5 histone deacetylase 5
HEATR3 HEAT repeat containing 3
HIST1H1D histone cluster 1, H1d
HIST1H4C histone cluster 1, H4c
HOXC8 homeobox C8
HPS6 Hermansky-Pudlak syndrome 6
IL10RB interleukin 10 receptor, beta
IMPACT impact RWD domain protein
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KLF13 Kruppel-like factor 13
L2HGDH L-2-hydroxyglutarate dehydrogenase
MANEA mannosidase, endo-alpha
MCTP1 multiple C2 domains, transmembrane 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MPI mannose phosphate isomerase
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MTG1 mitochondrial ribosome-associated GTPase 1
MYL9 myosin, light chain 9, regulatory
MYLIP myosin regulatory light chain interacting protein
MYLK myosin light chain kinase
NDE1 nudE neurodevelopment protein 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NT5C 5', 3'-nucleotidase, cytosolic
NTSR1 neurotensin receptor 1 (high affinity)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAQR6 progestin and adipoQ receptor family member VI
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PNPLA6 patatin-like phospholipase domain containing 6
PPCDC phosphopantothenoylcysteine decarboxylase
PRR15L proline rich 15-like
PYCRL pyrroline-5-carboxylate reductase-like
RAB23 RAB23, member RAS oncogene family
RAPSN receptor-associated protein of the synapse
RFTN1 raftlin, lipid raft linker 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAGB Ras-related GTP binding B
SAYSD1 SAYSVFN motif domain containing 1
SCAND1 SCAN domain containing 1
SCEL sciellin
SCYL2 SCY1-like 2 (S. cerevisiae)
SDCCAG3 serologically defined colon cancer antigen 3
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC30A1 solute carrier family 30 (zinc transporter), member 1
THEM6 thioesterase superfamily member 6
TICAM1 toll-like receptor adaptor molecule 1
TM7SF3 transmembrane 7 superfamily member 3
TMC5 transmembrane channel-like 5
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM45 tripartite motif containing 45
ULBP2 UL16 binding protein 2
WDR46 WD repeat domain 46
ZBED1 zinc finger, BED-type containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZNF16 zinc finger protein 16
ZNF217 zinc finger protein 217
ZNF606 zinc finger protein 606
ZNF668 zinc finger protein 668
ZNF76 zinc finger protein 76
ZW10 zw10 kinetochore protein