cinchonidine-1780 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the cinchonidine-1780 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX3 acyl-CoA oxidase 3, pristanoyl
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
AKAP10 A kinase (PRKA) anchor protein 10
ALOXE3 arachidonate lipoxygenase 3
AMBRA1 autophagy/beclin-1 regulator 1
APOC4 apolipoprotein C-IV
ARTN artemin
ATXN1 ataxin 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C1QTNF3 C1q and tumor necrosis factor related protein 3
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAPN10 calpain 10
CDHR2 cadherin-related family member 2
CENPI centromere protein I
CLCN7 chloride channel, voltage-sensitive 7
CLDN15 claudin 15
COL9A2 collagen, type IX, alpha 2
COPZ2 coatomer protein complex, subunit zeta 2
CPOX coproporphyrinogen oxidase
CTNNBIP1 catenin, beta interacting protein 1
CXCR3 chemokine (C-X-C motif) receptor 3
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DUSP2 dual specificity phosphatase 2
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
ERCC6L excision repair cross-complementation group 6-like
FAM189A2 family with sequence similarity 189, member A2
FASTK Fas-activated serine/threonine kinase
FMOD fibromodulin
GCLM glutamate-cysteine ligase, modifier subunit
GLIPR1 GLI pathogenesis-related 1
GLS glutaminase
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GMEB1 glucocorticoid modulatory element binding protein 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GP2 glycoprotein 2 (zymogen granule membrane)
HDAC5 histone deacetylase 5
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IRF2BP1 interferon regulatory factor 2 binding protein 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0195 KIAA0195
KLHL21 kelch-like family member 21
KRT32 keratin 32, type I
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LAT2 linker for activation of T cells family, member 2
LENEP lens epithelial protein
LGALS9 lectin, galactoside-binding, soluble, 9
LOXL3 lysyl oxidase-like 3
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST2 microtubule associated serine/threonine kinase 2
MBNL2 muscleblind-like splicing regulator 2
MYL10 myosin, light chain 10, regulatory
NCOA3 nuclear receptor coactivator 3
NRGN neurogranin (protein kinase C substrate, RC3)
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
PALM paralemmin
PDIA4 protein disulfide isomerase family A, member 4
PER1 period circadian clock 1
PHKG1 phosphorylase kinase, gamma 1 (muscle)
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PKNOX2 PBX/knotted 1 homeobox 2
PLA2G15 phospholipase A2, group XV
PLXNA1 plexin A1
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PTK2 protein tyrosine kinase 2
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB6B RAB6B, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
SLC10A3 solute carrier family 10, member 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPTB spectrin, beta, erythrocytic
STARD5 StAR-related lipid transfer (START) domain containing 5
SUGP1 SURP and G patch domain containing 1
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNIK TRAF2 and NCK interacting kinase
TNN tenascin N
TNNT1 troponin T type 1 (skeletal, slow)
TOP3A topoisomerase (DNA) III alpha
TRD T cell receptor delta locus
TUBA3C tubulin, alpha 3c
TULP3 tubby like protein 3
U2AF2 U2 small nuclear RNA auxiliary factor 2
WWP2 WW domain containing E3 ubiquitin protein ligase 2
YLPM1 YLP motif containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF142 zinc finger protein 142
ZNF419 zinc finger protein 419
ZNF614 zinc finger protein 614
ZNF764 zinc finger protein 764

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACP2 acid phosphatase 2, lysosomal
ACVR2B activin A receptor, type IIB
ANKFY1 ankyrin repeat and FYVE domain containing 1
APIP APAF1 interacting protein
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGAP15 Rho GTPase activating protein 15
ATXN2 ataxin 2
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCL10 B-cell CLL/lymphoma 10
BMS1 BMS1 ribosome biogenesis factor
C6ORF47 chromosome 6 open reading frame 47
CAPN1 calpain 1, (mu/I) large subunit
CASZ1 castor zinc finger 1
CD38 CD38 molecule
CEP83 centrosomal protein 83kDa
CNPY3 canopy FGF signaling regulator 3
CS citrate synthase
DERL2 derlin 2
DNAAF2 dynein, axonemal, assembly factor 2
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
FAM222B family with sequence similarity 222, member B
FAM46A family with sequence similarity 46, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF4 fibroblast growth factor 4
FOXK2 forkhead box K2
FPGS folylpolyglutamate synthase
FURIN furin (paired basic amino acid cleaving enzyme)
FXN frataxin
GPATCH2 G patch domain containing 2
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GTF2I general transcription factor IIi
HSPB1 heat shock 27kDa protein 1
IGKV1D-13 immunoglobulin kappa variable 1D-13
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL18 interleukin 18
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INPP1 inositol polyphosphate-1-phosphatase
ISOC2 isochorismatase domain containing 2
KAT2A K(lysine) acetyltransferase 2A
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCTD3 potassium channel tetramerization domain containing 3
KDM7A lysine (K)-specific demethylase 7A
KIFAP3 kinesin-associated protein 3
LAS1L LAS1-like (S. cerevisiae)
LBR lamin B receptor
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
MAPK3 mitogen-activated protein kinase 3
MAPKAP1 mitogen-activated protein kinase associated protein 1
MMP9 matrix metallopeptidase 9
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MRPL35 mitochondrial ribosomal protein L35
MRPS34 mitochondrial ribosomal protein S34
MTERF1 mitochondrial transcription termination factor 1
MYBBP1A MYB binding protein (P160) 1a
NECAB3 N-terminal EF-hand calcium binding protein 3
NHEJ1 nonhomologous end-joining factor 1
NRBP1 nuclear receptor binding protein 1
OPHN1 oligophrenin 1
PAK1IP1 PAK1 interacting protein 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDHX pyruvate dehydrogenase complex, component X
PES1 pescadillo ribosomal biogenesis factor 1
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PRCC papillary renal cell carcinoma (translocation-associated)
PRTN3 proteinase 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RASA2 RAS p21 protein activator 2
RNF170 ring finger protein 170
RNF44 ring finger protein 44
RNMTL1 RNA methyltransferase like 1
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RUVBL1 RuvB-like AAA ATPase 1
SDHAF3 succinate dehydrogenase complex assembly factor 3
SLC35F2 solute carrier family 35, member F2
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNX17 sorting nexin 17
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPON2 spondin 2, extracellular matrix protein
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
TIAM2 T-cell lymphoma invasion and metastasis 2
TMEM109 transmembrane protein 109
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
UROS uroporphyrinogen III synthase
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WDR18 WD repeat domain 18
ZEB2 zinc finger E-box binding homeobox 2
ZNF14 zinc finger protein 14
ZNF175 zinc finger protein 175