| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the cinchonine-3988 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| APOA4 | apolipoprotein A-IV |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAPN3 | calpain 3, (p94) |
| CCDC186 | coiled-coil domain containing 186 |
| CD177 | CD177 molecule |
| CD58 | CD58 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK13 | cyclin-dependent kinase 13 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CHODL | chondrolectin |
| CIB2 | calcium and integrin binding family member 2 |
| COL3A1 | collagen, type III, alpha 1 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DOCK10 | dedicator of cytokinesis 10 |
| DTNB | dystrobrevin, beta |
| E2F1 | E2F transcription factor 1 |
| EDNRA | endothelin receptor type A |
| EPHA5 | EPH receptor A5 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EXOC7 | exocyst complex component 7 |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FAS | Fas cell surface death receptor |
| GAB1 | GRB2-associated binding protein 1 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GFI1 | growth factor independent 1 transcription repressor |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPM6B | glycoprotein M6B |
| GPR17 | G protein-coupled receptor 17 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HCFC1 | host cell factor C1 |
| HMOX1 | heme oxygenase 1 |
| HOXD3 | homeobox D3 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IRS4 | insulin receptor substrate 4 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KIF13A | kinesin family member 13A |
| KRT8P12 | keratin 8 pseudogene 12 |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LOXL3 | lysyl oxidase-like 3 |
| LRRN3 | leucine rich repeat neuronal 3 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MATN3 | matrilin 3 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| NGLY1 | N-glycanase 1 |
| NOL12 | nucleolar protein 12 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NRN1 | neuritin 1 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OGDHL | oxoglutarate dehydrogenase-like |
| OSBPL10 | oxysterol binding protein-like 10 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PGK2 | phosphoglycerate kinase 2 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PKLR | pyruvate kinase, liver and RBC |
| POLQ | polymerase (DNA directed), theta |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| RABGAP1 | RAB GTPase activating protein 1 |
| RBM4 | RNA binding motif protein 4 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RUNX1 | runt-related transcription factor 1 |
| RXRB | retinoid X receptor, beta |
| SCAF4 | SR-related CTD-associated factor 4 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SEPP1 | selenoprotein P, plasma, 1 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPATA6 | spermatogenesis associated 6 |
| TACR1 | tachykinin receptor 1 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| THBD | thrombomodulin |
| THRB | thyroid hormone receptor, beta |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM66 | tripartite motif containing 66 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TUBA3C | tubulin, alpha 3c |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZCCHC11 | zinc finger, CCHC domain containing 11 |
| ZNF500 | zinc finger protein 500 |
| Symbol | Name |
|---|---|
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| ALAS1 | 5'-aminolevulinate synthase 1 |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ARRB2 | arrestin, beta 2 |
| AXIN1 | axin 1 |
| B9D2 | B9 protein domain 2 |
| BST1 | bone marrow stromal cell antigen 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CA9 | carbonic anhydrase IX |
| CAPN15 | calpain 15 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CBX8 | chromobox homolog 8 |
| CD68 | CD68 molecule |
| CD70 | CD70 molecule |
| CDON | cell adhesion associated, oncogene regulated |
| CISH | cytokine inducible SH2-containing protein |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDN | dendrin |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| EFNA3 | ephrin-A3 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GRM4 | glutamate receptor, metabotropic 4 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IFI44L | interferon-induced protein 44-like |
| IFT54 | intraflagellar transport 54 |
| IL17RB | interleukin 17 receptor B |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KRT15 | keratin 15, type I |
| KRT33A | keratin 33A, type I |
| LAMC3 | laminin, gamma 3 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MYO1F | myosin IF |
| NDRG1 | N-myc downstream regulated 1 |
| NRTN | neurturin |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PICK1 | protein interacting with PRKCA 1 |
| PLD3 | phospholipase D family, member 3 |
| POLL | polymerase (DNA directed), lambda |
| QSER1 | glutamine and serine rich 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF25 | ring finger protein 25 |
| SELL | selectin L |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLAMF7 | SLAM family member 7 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| STAB2 | stabilin 2 |
| STEAP4 | STEAP family member 4 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TEP1 | telomerase-associated protein 1 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TRAIP | TRAF interacting protein |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WDR18 | WD repeat domain 18 |
| WDR25 | WD repeat domain 25 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF268 | zinc finger protein 268 |
| ZNF506 | zinc finger protein 506 |
| ZNF529 | zinc finger protein 529 |
| ZNF747 | zinc finger protein 747 |
