cinnarizine-1558 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the cinnarizine-1558 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ACAN aggrecan
ACP6 acid phosphatase 6, lysophosphatidic
ACRV1 acrosomal vesicle protein 1
ADAP1 ArfGAP with dual PH domains 1
AKAP17A A kinase (PRKA) anchor protein 17A
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BATF basic leucine zipper transcription factor, ATF-like
BBC3 BCL2 binding component 3
BMP15 bone morphogenetic protein 15
BMPR1A bone morphogenetic protein receptor, type IA
BTN3A2 butyrophilin, subfamily 3, member A2
C20ORF27 chromosome 20 open reading frame 27
C4BPA complement component 4 binding protein, alpha
CCDC7 coiled-coil domain containing 7
CCPG1 cell cycle progression 1
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD47 CD47 molecule
CENPI centromere protein I
CLDN10 claudin 10
CLEC7A C-type lectin domain family 7, member A
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DGCR8 DGCR8 microprocessor complex subunit
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DST dystonin
EFNB3 ephrin-B3
ELK1 ELK1, member of ETS oncogene family
FAM153A family with sequence similarity 153, member A
FASTK Fas-activated serine/threonine kinase
FMO4 flavin containing monooxygenase 4
GALR3 galanin receptor 3
GFOD2 glucose-fructose oxidoreductase domain containing 2
GNB5 guanine nucleotide binding protein (G protein), beta 5
GSK3A glycogen synthase kinase 3 alpha
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCFC1 host cell factor C1
HOOK2 hook microtubule-tethering protein 2
HOXA10 homeobox A10
HRSP12 heat-responsive protein 12
KAT8 K(lysine) acetyltransferase 8
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD12 potassium channel tetramerization domain containing 12
LINC00339 long intergenic non-protein coding RNA 339
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP7D3 MAP7 domain containing 3
MBOAT7 membrane bound O-acyltransferase domain containing 7
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEGF6 multiple EGF-like-domains 6
MFN1 mitofusin 1
MMP25 matrix metallopeptidase 25
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MXD4 MAX dimerization protein 4
MYH14 myosin, heavy chain 14, non-muscle
N4BP1 NEDD4 binding protein 1
NADK NAD kinase
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NSUN6 NOP2/Sun domain family, member 6
OR10J1 olfactory receptor, family 10, subfamily J, member 1
ORAI2 ORAI calcium release-activated calcium modulator 2
PARD3 par-3 family cell polarity regulator
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PFDN1 prefoldin subunit 1
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCE protein kinase C, epsilon
PRKCQ protein kinase C, theta
RAB1B RAB1B, member RAS oncogene family
RAB36 RAB36, member RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
REEP1 receptor accessory protein 1
RHOH ras homolog family member H
RIN1 Ras and Rab interactor 1
RSAD1 radical S-adenosyl methionine domain containing 1
SEC23IP SEC23 interacting protein
SFSWAP splicing factor, suppressor of white-apricot family
SIDT2 SID1 transmembrane family, member 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC38A7 solute carrier family 38, member 7
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPN sialophorin
ST14 suppression of tumorigenicity 14 (colon carcinoma)
TCAF1 TRPM8 channel-associated factor 1
TCP10L t-complex 10-like
TM2D1 TM2 domain containing 1
TPM1 tropomyosin 1 (alpha)
TRIM29 tripartite motif containing 29
UBOX5 U-box domain containing 5
UNC13B unc-13 homolog B (C. elegans)
USF2 upstream transcription factor 2, c-fos interacting
WDR13 WD repeat domain 13
WNK1 WNK lysine deficient protein kinase 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZBED1 zinc finger, BED-type containing 1
ZC3H7B zinc finger CCCH-type containing 7B
ZNF124 zinc finger protein 124
ZNF432 zinc finger protein 432
ZNF460 zinc finger protein 460
ZNF574 zinc finger protein 574

decreased expression

Symbol Name
ABHD11 abhydrolase domain containing 11
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACYP1 acylphosphatase 1, erythrocyte (common) type
AES amino-terminal enhancer of split
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ATP11B ATPase, class VI, type 11B
ATXN2 ataxin 2
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1ORF174 chromosome 1 open reading frame 174
C4ORF29 chromosome 4 open reading frame 29
CAPN1 calpain 1, (mu/I) large subunit
CD2AP CD2-associated protein
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDT1 chromatin licensing and DNA replication factor 1
CEND1 cell cycle exit and neuronal differentiation 1
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CINP cyclin-dependent kinase 2 interacting protein
CLTCL1 clathrin, heavy chain-like 1
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNPY3 canopy FGF signaling regulator 3
DIXDC1 DIX domain containing 1
DRAM1 DNA-damage regulated autophagy modulator 1
ECT2 epithelial cell transforming 2
EFTUD1 elongation factor Tu GTP binding domain containing 1
FADS2 fatty acid desaturase 2
FAM188A family with sequence similarity 188, member A
FBXL14 F-box and leucine-rich repeat protein 14
FBXO5 F-box protein 5
FURIN furin (paired basic amino acid cleaving enzyme)
GSTCD glutathione S-transferase, C-terminal domain containing
GUSBP3 glucuronidase, beta pseudogene 3
IGFLR1 IGF-like family receptor 1
IMPACT impact RWD domain protein
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KIFC1 kinesin family member C1
LMBR1L limb development membrane protein 1-like
LPCAT1 lysophosphatidylcholine acyltransferase 1
LXN latexin
MAGT1 magnesium transporter 1
MAST3 microtubule associated serine/threonine kinase 3
MEX3C mex-3 RNA binding family member C
MICB MHC class I polypeptide-related sequence B
MIS12 MIS12 kinetochore complex component
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MLPH melanophilin
MYL12B myosin, light chain 12B, regulatory
NFS1 NFS1 cysteine desulfurase
NOD1 nucleotide-binding oligomerization domain containing 1
OGFRL1 opioid growth factor receptor-like 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PCTP phosphatidylcholine transfer protein
PHF21A PHD finger protein 21A
PHLDA2 pleckstrin homology-like domain, family A, member 2
PHYH phytanoyl-CoA 2-hydroxylase
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POTEKP POTE ankyrin domain family, member K, pseudogene
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTGES2 prostaglandin E synthase 2
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RPL23AP32 ribosomal protein L23a pseudogene 32
SASH1 SAM and SH3 domain containing 1
SECISBP2 SECIS binding protein 2
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLN sarcolipin
SNX15 sorting nexin 15
SPA17 sperm autoantigenic protein 17
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STK26 serine/threonine protein kinase 26
STRN4 striatin, calmodulin binding protein 4
TJP2 tight junction protein 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM14A transmembrane protein 14A
TRAPPC11 trafficking protein particle complex 11
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSC22D1 TSC22 domain family, member 1
TTF2 transcription termination factor, RNA polymerase II
UBE3C ubiquitin protein ligase E3C
UBQLN4 ubiquilin 4
WDR19 WD repeat domain 19
ZNF175 zinc finger protein 175
ZNF197 zinc finger protein 197
ZNF33B zinc finger protein 33B
ZNF426 zinc finger protein 426
ZNF611 zinc finger protein 611
ZNF804A zinc finger protein 804A
ZNF85 zinc finger protein 85