cinnarizine-3175 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the cinnarizine-3175 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
AFF1 AF4/FMR2 family, member 1
ARID4B AT rich interactive domain 4B (RBP1-like)
ARTN artemin
ASTN1 astrotactin 1
ATXN8OS ATXN8 opposite strand (non-protein coding)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BGN biglycan
BTN3A2 butyrophilin, subfamily 3, member A2
C17ORF53 chromosome 17 open reading frame 53
CALCR calcitonin receptor
CALD1 caldesmon 1
CD28 CD28 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CLCA2 chloride channel accessory 2
CLCN7 chloride channel, voltage-sensitive 7
CNTNAP1 contactin associated protein 1
CNTNAP3B contactin associated protein-like 3B
CST1 cystatin SN
CTSO cathepsin O
DMRT1 doublesex and mab-3 related transcription factor 1
DNASE1L2 deoxyribonuclease I-like 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FAIM2 Fas apoptotic inhibitory molecule 2
FAM13A family with sequence similarity 13, member A
FST follistatin
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GM2A GM2 ganglioside activator
GPR21 G protein-coupled receptor 21
GRM1 glutamate receptor, metabotropic 1
HIST1H3J histone cluster 1, H3j
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA4 homeobox A4
ICOS inducible T-cell co-stimulator
JMJD6 jumonji domain containing 6
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIAA0040 KIAA0040
KLF1 Kruppel-like factor 1 (erythroid)
KRT19P2 keratin 19 pseudogene 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMD2 LIM domain containing 2
LOXL2 lysyl oxidase-like 2
MAPK14 mitogen-activated protein kinase 14
MAPK7 mitogen-activated protein kinase 7
MIR622 microRNA 622
MTL5 metallothionein-like 5, testis-specific (tesmin)
NKX2-5 NK2 homeobox 5
NPY neuropeptide Y
NT5M 5',3'-nucleotidase, mitochondrial
OLFM1 olfactomedin 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSGIN1 oxidative stress induced growth inhibitor 1
OSMR oncostatin M receptor
OTOR otoraplin
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PALM paralemmin
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PCBP3 poly(rC) binding protein 3
PCDH1 protocadherin 1
PCDH12 protocadherin 12
PCDH17 protocadherin 17
PCSK6 proprotein convertase subtilisin/kexin type 6
PHC3 polyhomeotic homolog 3 (Drosophila)
PIGR polymeric immunoglobulin receptor
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PRX periaxin
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PVR poliovirus receptor
RAB7A RAB7A, member RAS oncogene family
RBMS3 RNA binding motif, single stranded interacting protein 3
RBP4 retinol binding protein 4, plasma
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS14 regulator of G-protein signaling 14
RPL35A ribosomal protein L35a
RUNX1 runt-related transcription factor 1
SAMD4A sterile alpha motif domain containing 4A
SCGB1D1 secretoglobin, family 1D, member 1
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SLAMF7 SLAM family member 7
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SNAI2 snail family zinc finger 2
SOX17 SRY (sex determining region Y)-box 17
STRN striatin, calmodulin binding protein
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBD thrombomodulin
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRBC1 T cell receptor beta constant 1
TRIM68 tripartite motif containing 68
TSNAXIP1 translin-associated factor X interacting protein 1
UPB1 ureidopropionase, beta
VGLL1 vestigial-like family member 1
VSX1 visual system homeobox 1
WIPI2 WD repeat domain, phosphoinositide interacting 2
XYLT1 xylosyltransferase I
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AKAP12 A kinase (PRKA) anchor protein 12
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANP32A-IT1 ANP32A intronic transcript 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASAP1-IT1 ASAP1 intronic transcript 1
BMP4 bone morphogenetic protein 4
C7ORF43 chromosome 7 open reading frame 43
C9ORF9 chromosome 9 open reading frame 9
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAMKV CaM kinase-like vesicle-associated
CAPN15 calpain 15
CCNK cyclin K
CCP110 centriolar coiled coil protein 110kDa
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD53 CD53 molecule
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CEP97 centrosomal protein 97kDa
CHRM3 cholinergic receptor, muscarinic 3
CLDN15 claudin 15
CRY2 cryptochrome circadian clock 2
DGAT1 diacylglycerol O-acyltransferase 1
DMTN dematin actin binding protein
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ELP6 elongator acetyltransferase complex subunit 6
ENO2 enolase 2 (gamma, neuronal)
FAM131A family with sequence similarity 131, member A
FGGY FGGY carbohydrate kinase domain containing
FKBP5 FK506 binding protein 5
FLJ11710 uncharacterized protein FLJ11710
GUSBP3 glucuronidase, beta pseudogene 3
HELZ helicase with zinc finger
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HMHA1 histocompatibility (minor) HA-1
HMOX1 heme oxygenase 1
HOXC8 homeobox C8
IFT140 intraflagellar transport 140
INCENP inner centromere protein antigens 135/155kDa
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITPKB inositol-trisphosphate 3-kinase B
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM5C lysine (K)-specific demethylase 5C
KDM8 lysine (K)-specific demethylase 8
LAMB3 laminin, beta 3
LDHB lactate dehydrogenase B
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LYZ lysozyme
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP1S microtubule-associated protein 1S
MCOLN3 mucolipin 3
MICALL2 MICAL-like 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPO myeloperoxidase
MTCL1 microtubule crosslinking factor 1
MUC3A mucin 3A, cell surface associated
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPIPB3 nuclear pore complex interacting protein family, member B3
NRSN2 neurensin 2
NT5E 5'-nucleotidase, ecto (CD73)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OVGP1 oviductal glycoprotein 1, 120kDa
PMM1 phosphomannomutase 1
PMP22 peripheral myelin protein 22
POLL polymerase (DNA directed), lambda
PROCR protein C receptor, endothelial
RAD54L2 RAD54-like 2 (S. cerevisiae)
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPAP1 RNA polymerase II associated protein 1
RPAP2 RNA polymerase II associated protein 2
SDC3 syndecan 3
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMYD5 SMYD family member 5
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SRD5A3 steroid 5 alpha-reductase 3
SRGN serglycin
STX1A syntaxin 1A (brain)
SYT17 synaptotagmin XVII
TEAD3 TEA domain family member 3
TOM1 target of myb1 (chicken)
TPST2 tyrosylprotein sulfotransferase 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC22D4 TSC22 domain family, member 4
TTC33 tetratricopeptide repeat domain 33
TUBG2 tubulin, gamma 2
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
ZBTB44 zinc finger and BTB domain containing 44
ZNF227 zinc finger protein 227
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF446 zinc finger protein 446
ZNF768 zinc finger protein 768