| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the cinnarizine-7174 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
| ABHD17B | abhydrolase domain containing 17B |
| ADCY6 | adenylate cyclase 6 |
| AK2 | adenylate kinase 2 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C4 | aldo-keto reductase family 1, member C4 |
| ANXA1 | annexin A1 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATM | ATM serine/threonine kinase |
| B9D1 | B9 protein domain 1 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CD44 | CD44 molecule (Indian blood group) |
| CDHR2 | cadherin-related family member 2 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| DAGLA | diacylglycerol lipase, alpha |
| DAPK2 | death-associated protein kinase 2 |
| DCX | doublecortin |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ECE1 | endothelin converting enzyme 1 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM131A | family with sequence similarity 131, member A |
| FAM49B | family with sequence similarity 49, member B |
| FBLN1 | fibulin 1 |
| FBXO2 | F-box protein 2 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FILIP1L | filamin A interacting protein 1-like |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HFE | hemochromatosis |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| INHBC | inhibin, beta C |
| IPO9 | importin 9 |
| IRS2 | insulin receptor substrate 2 |
| KIAA0141 | KIAA0141 |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LRRC61 | leucine rich repeat containing 61 |
| MED6 | mediator complex subunit 6 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MXD4 | MAX dimerization protein 4 |
| NGDN | neuroguidin, EIF4E binding protein |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| OMG | oligodendrocyte myelin glycoprotein |
| OSMR | oncostatin M receptor |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARG | poly (ADP-ribose) glycohydrolase |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHF20 | PHD finger protein 20 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PSEN2 | presenilin 2 |
| PSPH | phosphoserine phosphatase |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RAB6A | RAB6A, member RAS oncogene family |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RARG | retinoic acid receptor, gamma |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 |
| RGS12 | regulator of G-protein signaling 12 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SCARB1 | scavenger receptor class B, member 1 |
| SDS | serine dehydratase |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SGSM3 | small G protein signaling modulator 3 |
| SH3BP2 | SH3-domain binding protein 2 |
| SKIL | SKI-like proto-oncogene |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SORT1 | sortilin 1 |
| SOX13 | SRY (sex determining region Y)-box 13 |
| SP100 | SP100 nuclear antigen |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRCAP | Snf2-related CREBBP activator protein |
| SRI | sorcin |
| SRPR | signal recognition particle receptor (docking protein) |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STK3 | serine/threonine kinase 3 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TCF3 | transcription factor 3 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TK2 | thymidine kinase 2, mitochondrial |
| TMEM2 | transmembrane protein 2 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF230 | zinc finger protein 230 |
| Symbol | Name |
|---|---|
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ANKRD28 | ankyrin repeat domain 28 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCORL1 | BCL6 corepressor-like 1 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCNJ | cyclin J |
| CDK3 | cyclin-dependent kinase 3 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLDN4 | claudin 4 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COBL | cordon-bleu WH2 repeat protein |
| CTSK | cathepsin K |
| CUEDC1 | CUE domain containing 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DSPP | dentin sialophosphoprotein |
| DUSP8 | dual specificity phosphatase 8 |
| DVL1 | dishevelled segment polarity protein 1 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGGY | FGGY carbohydrate kinase domain containing |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPR19 | G protein-coupled receptor 19 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| HIST1H2AJ | histone cluster 1, H2aj |
| HSPA2 | heat shock 70kDa protein 2 |
| IL15RA | interleukin 15 receptor, alpha |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IPO8 | importin 8 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JADE1 | jade family PHD finger 1 |
| JMJD4 | jumonji domain containing 4 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0922 | KIAA0922 |
| KIFC1 | kinesin family member C1 |
| KIZ | kizuna centrosomal protein |
| KLHL2 | kelch-like family member 2 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MED15 | mediator complex subunit 15 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MPC1 | mitochondrial pyruvate carrier 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RNF123 | ring finger protein 123 |
| RNF25 | ring finger protein 25 |
| RNF31 | ring finger protein 31 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RWDD3 | RWD domain containing 3 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STXBP1 | syntaxin binding protein 1 |
| TBX19 | T-box 19 |
| THBS3 | thrombospondin 3 |
| TMEM177 | transmembrane protein 177 |
| TMEM51 | transmembrane protein 51 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAIP | TRAF interacting protein |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC23 | tetratricopeptide repeat domain 23 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| USB1 | U6 snRNA biogenesis 1 |
| WDR60 | WD repeat domain 60 |
| XAB2 | XPA binding protein 2 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF219 | zinc finger protein 219 |
| ZNF428 | zinc finger protein 428 |
| ZNF668 | zinc finger protein 668 |
| ZNF85 | zinc finger protein 85 |
