| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the cinoxacin-3463 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACE2 | angiotensin I converting enzyme 2 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARMC4 | armadillo repeat containing 4 |
| BTBD7 | BTB (POZ) domain containing 7 |
| C1ORF68 | chromosome 1 open reading frame 68 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CHD3 | chromodomain helicase DNA binding protein 3 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLEC4E | C-type lectin domain family 4, member E |
| DAGLA | diacylglycerol lipase, alpha |
| DCAF8 | DDB1 and CUL4 associated factor 8 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DPYS | dihydropyrimidinase |
| EGFR | epidermal growth factor receptor |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| F2R | coagulation factor II (thrombin) receptor |
| FAM214B | family with sequence similarity 214, member B |
| FBXO9 | F-box protein 9 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GAS6 | growth arrest-specific 6 |
| GRK5 | G protein-coupled receptor kinase 5 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HIST1H1D | histone cluster 1, H1d |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HNMT | histamine N-methyltransferase |
| HOXC8 | homeobox C8 |
| IGHM | immunoglobulin heavy constant mu |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| JAK2 | Janus kinase 2 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KLHL22 | kelch-like family member 22 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRRC8B | leucine rich repeat containing 8 family, member B |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MEFV | Mediterranean fever |
| METTL7A | methyltransferase like 7A |
| MON2 | MON2 homolog (S. cerevisiae) |
| MTRF1L | mitochondrial translational release factor 1-like |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NEB | nebulin |
| NF1 | neurofibromin 1 |
| NGLY1 | N-glycanase 1 |
| NKX3-2 | NK3 homeobox 2 |
| PCDHB3 | protocadherin beta 3 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PML | promyelocytic leukemia |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGS12 | regulator of G-protein signaling 12 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RNF2 | ring finger protein 2 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SETD1B | SET domain containing 1B |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIVA1 | SIVA1, apoptosis-inducing factor |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOX13 | SRY (sex determining region Y)-box 13 |
| SPATA5L1 | spermatogenesis associated 5-like 1 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TAPBP | TAP binding protein (tapasin) |
| TAZ | tafazzin |
| TGFB2 | transforming growth factor, beta 2 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TM2D1 | TM2 domain containing 1 |
| TMC6 | transmembrane channel-like 6 |
| TRD | T cell receptor delta locus |
| UBE3A | ubiquitin protein ligase E3A |
| UBXN1 | UBX domain protein 1 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VLDLR | very low density lipoprotein receptor |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF277 | zinc finger protein 277 |
| ZNF428 | zinc finger protein 428 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCORL1 | BCL6 corepressor-like 1 |
| BTBD3 | BTB (POZ) domain containing 3 |
| C5 | complement component 5 |
| C5AR2 | complement component 5a receptor 2 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCDC28A | coiled-coil domain containing 28A |
| CCDC47 | coiled-coil domain containing 47 |
| CCDC53 | coiled-coil domain containing 53 |
| CDK3 | cyclin-dependent kinase 3 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLDN15 | claudin 15 |
| CORT | cortistatin |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 |
| ECSIT | ECSIT signalling integrator |
| EFHD2 | EF-hand domain family, member D2 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ELMO3 | engulfment and cell motility 3 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC5 | excision repair cross-complementation group 5 |
| FBXO31 | F-box protein 31 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| G6PD | glucose-6-phosphate dehydrogenase |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GTPBP2 | GTP binding protein 2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC4 | histone deacetylase 4 |
| HIST1H3B | histone cluster 1, H3b |
| INSIG2 | insulin induced gene 2 |
| IREB2 | iron-responsive element binding protein 2 |
| IRF6 | interferon regulatory factor 6 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KIAA0513 | KIAA0513 |
| KIF13B | kinesin family member 13B |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYRM9 | LYR motif containing 9 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAPK3 | mitogen-activated protein kinase 3 |
| MRPS2 | mitochondrial ribosomal protein S2 |
| NKRF | NFKB repressing factor |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| PC | pyruvate carboxylase |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PMCH | pro-melanin-concentrating hormone |
| PRR7 | proline rich 7 (synaptic) |
| PRSS16 | protease, serine, 16 (thymus) |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
| RARS | arginyl-tRNA synthetase |
| RASA2 | RAS p21 protein activator 2 |
| RBM42 | RNA binding motif protein 42 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STBD1 | starch binding domain 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TESC | tescalcin |
| TMEM2 | transmembrane protein 2 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSPYL2 | TSPY-like 2 |
| TUBA3C | tubulin, alpha 3c |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF574 | zinc finger protein 574 |
| ZNF768 | zinc finger protein 768 |
