cinoxacin-5783 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the cinoxacin-5783 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
AFF1 AF4/FMR2 family, member 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARNT aryl hydrocarbon receptor nuclear translocator
AURKC aurora kinase C
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C5ORF42 chromosome 5 open reading frame 42
C7ORF69 chromosome 7 open reading frame 69
C8B complement component 8, beta polypeptide
C9ORF9 chromosome 9 open reading frame 9
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD1A CD1a molecule
CDK20 cyclin-dependent kinase 20
CFAP69 cilia and flagella associated protein 69
CIZ1 CDKN1A interacting zinc finger protein 1
CLPS colipase, pancreatic
COL14A1 collagen, type XIV, alpha 1
CRYGD crystallin, gamma D
CSPG4 chondroitin sulfate proteoglycan 4
CYTH4 cytohesin 4
DMC1 DNA meiotic recombinase 1
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DPY19L1 dpy-19-like 1 (C. elegans)
DVL2 dishevelled segment polarity protein 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFR3B EFR3 homolog B (S. cerevisiae)
ELL2 elongation factor, RNA polymerase II, 2
FILIP1L filamin A interacting protein 1-like
FLJ21369 uncharacterized protein FLJ21369
FOXD2 forkhead box D2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GATA3 GATA binding protein 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HPX hemopexin
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
INE1 inactivation escape 1 (non-protein coding)
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KIAA1644 KIAA1644
KISS1 KiSS-1 metastasis-suppressor
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LOC100131532 uncharacterized LOC100131532
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MECOM MDS1 and EVI1 complex locus
MED25 mediator complex subunit 25
MED28 mediator complex subunit 28
MEF2C myocyte enhancer factor 2C
MLXIP MLX interacting protein
MUC8 mucin 8
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NOP16 NOP16 nucleolar protein
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OMG oligodendrocyte myelin glycoprotein
OR52A1 olfactory receptor, family 52, subfamily A, member 1
OR7C1 olfactory receptor, family 7, subfamily C, member 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PLXND1 plexin D1
PRB4 proline-rich protein BstNI subfamily 4
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RAD23B RAD23 homolog B (S. cerevisiae)
RBPMS RNA binding protein with multiple splicing
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RHBDD3 rhomboid domain containing 3
SKIL SKI-like proto-oncogene
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMIM14 small integral membrane protein 14
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
TAGLN3 transgelin 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
TYMS thymidylate synthetase
USP22 ubiquitin specific peptidase 22
VAC14 Vac14 homolog (S. cerevisiae)
VCX2 variable charge, X-linked 2
WRNIP1 Werner helicase interacting protein 1
XYLB xylulokinase homolog (H. influenzae)
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF137P zinc finger protein 137, pseudogene
ZNF224 zinc finger protein 224

decreased expression

Symbol Name
ANXA2P1 annexin A2 pseudogene 1
ARHGAP10 Rho GTPase activating protein 10
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
C17ORF85 chromosome 17 open reading frame 85
C5 complement component 5
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CCNT1 cyclin T1
CDKL3 cyclin-dependent kinase-like 3
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CINP cyclin-dependent kinase 2 interacting protein
CORO1A coronin, actin binding protein, 1A
CORO2A coronin, actin binding protein, 2A
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DDN dendrin
DENND4A DENN/MADD domain containing 4A
EHF ets homologous factor
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM155A family with sequence similarity 155, member A
FAM204A family with sequence similarity 204, member A
FAM53B family with sequence similarity 53, member B
FGF13 fibroblast growth factor 13
FKBP10 FK506 binding protein 10, 65 kDa
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPATCH2L G patch domain containing 2-like
GPR19 G protein-coupled receptor 19
GPR3 G protein-coupled receptor 3
GRTP1 growth hormone regulated TBC protein 1
GTF2I general transcription factor IIi
HIST1H1D histone cluster 1, H1d
HIST1H2AJ histone cluster 1, H2aj
HIST1H3B histone cluster 1, H3b
HIST1H3C histone cluster 1, H3c
IFI35 interferon-induced protein 35
IFI44L interferon-induced protein 44-like
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
JAM3 junctional adhesion molecule 3
KLC2 kinesin light chain 2
LAMC3 laminin, gamma 3
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINS lines homolog (Drosophila)
LOC257152 uncharacterized LOC257152
LRRK1 leucine-rich repeat kinase 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MRPL44 mitochondrial ribosomal protein L44
MVP major vault protein
MYO1D myosin ID
MYO1F myosin IF
NEK11 NIMA-related kinase 11
NHLRC2 NHL repeat containing 2
NPM3 nucleophosmin/nucleoplasmin 3
NT5M 5',3'-nucleotidase, mitochondrial
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSR2 odd-skipped related transciption factor 2
PC pyruvate carboxylase
PDE12 phosphodiesterase 12
PDGFRL platelet-derived growth factor receptor-like
PDLIM2 PDZ and LIM domain 2 (mystique)
PHEX phosphate regulating endopeptidase homolog, X-linked
PLCD1 phospholipase C, delta 1
PLD3 phospholipase D family, member 3
PODXL2 podocalyxin-like 2
PRAMEF11 PRAME family member 11
RAD54L2 RAD54-like 2 (S. cerevisiae)
RGCC regulator of cell cycle
RGS17 regulator of G-protein signaling 17
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SDC3 syndecan 3
SETBP1 SET binding protein 1
SLC12A8 solute carrier family 12, member 8
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SSBP3 single stranded DNA binding protein 3
STBD1 starch binding domain 1
STRN striatin, calmodulin binding protein
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TMEM53 transmembrane protein 53
TMEM57 transmembrane protein 57
TNS2 tensin 2
TRAF2 TNF receptor-associated factor 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPV6 transient receptor potential cation channel, subfamily V, member 6
ZBTB6 zinc finger and BTB domain containing 6
ZNF350 zinc finger protein 350
ZNF358 zinc finger protein 358
ZNF574 zinc finger protein 574
ZNF668 zinc finger protein 668
ZNF76 zinc finger protein 76
ZNF767P zinc finger family member 767, pseudogene
ZNF768 zinc finger protein 768
ZNF778 zinc finger protein 778