| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the cinoxacin-6257 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ARSB | arylsulfatase B |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAIAP3 | BAI1-associated protein 3 |
| BRCA1 | breast cancer 1, early onset |
| CABIN1 | calcineurin binding protein 1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLDN10 | claudin 10 |
| COL1A1 | collagen, type I, alpha 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| CYTH1 | cytohesin 1 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DNAL4 | dynein, axonemal, light chain 4 |
| ELK1 | ELK1, member of ETS oncogene family |
| EPHB3 | EPH receptor B3 |
| FAM134B | family with sequence similarity 134, member B |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FCAR | Fc fragment of IgA receptor |
| FGFR1 | fibroblast growth factor receptor 1 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GOSR1 | golgi SNAP receptor complex member 1 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HBS1L | HBS1-like translational GTPase |
| HFE | hemochromatosis |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL6ST | interleukin 6 signal transducer |
| IRF1 | interferon regulatory factor 1 |
| IRF5 | interferon regulatory factor 5 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMAN1 | lectin, mannose-binding, 1 |
| LMBR1L | limb development membrane protein 1-like |
| LPIN2 | lipin 2 |
| MANBA | mannosidase, beta A, lysosomal |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MAPK13 | mitogen-activated protein kinase 13 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MLF1 | myeloid leukemia factor 1 |
| NCBP1 | nuclear cap binding protein subunit 1, 80kDa |
| NDRG2 | NDRG family member 2 |
| NEUROD4 | neuronal differentiation 4 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLSCR3 | phospholipid scramblase 3 |
| POLQ | polymerase (DNA directed), theta |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRR4 | proline rich 4 (lacrimal) |
| RUNX1 | runt-related transcription factor 1 |
| SFXN3 | sideroflexin 3 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SH2B3 | SH2B adaptor protein 3 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMTN | smoothelin |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNN | stannin |
| SPPL2B | signal peptide peptidase like 2B |
| STS | steroid sulfatase (microsomal), isozyme S |
| SUGP1 | SURP and G patch domain containing 1 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TOM1 | target of myb1 (chicken) |
| TSPAN9 | tetraspanin 9 |
| TTC28 | tetratricopeptide repeat domain 28 |
| TWF1 | twinfilin actin binding protein 1 |
| USB1 | U6 snRNA biogenesis 1 |
| USP19 | ubiquitin specific peptidase 19 |
| WAS | Wiskott-Aldrich syndrome |
| WDR25 | WD repeat domain 25 |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZCCHC11 | zinc finger, CCHC domain containing 11 |
| ZNF423 | zinc finger protein 423 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABCB7 | ATP-binding cassette, sub-family B (MDR/TAP), member 7 |
| AHCTF1 | AT hook containing transcription factor 1 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CAPN5 | calpain 5 |
| CCDC15 | coiled-coil domain containing 15 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CROT | carnitine O-octanoyltransferase |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 |
| CTSC | cathepsin C |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNM1 | dynamin 1 |
| DNMBP | dynamin binding protein |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOSL1 | FOS-like antigen 1 |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| FZD4 | frizzled class receptor 4 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GID4 | GID complex subunit 4 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRAMD4 | GRAM domain containing 4 |
| HIST1H2BC | histone cluster 1, H2bc |
| IFT81 | intraflagellar transport 81 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IMPACT | impact RWD domain protein |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INO80D | INO80 complex subunit D |
| KLC2 | kinesin light chain 2 |
| KLHL21 | kelch-like family member 21 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYH9 | myosin, heavy chain 9, non-muscle |
| NAV2 | neuron navigator 2 |
| NCS1 | neuronal calcium sensor 1 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLD3 | phospholipase D family, member 3 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRPH | peripherin |
| PSKH1 | protein serine kinase H1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RBM41 | RNA binding motif protein 41 |
| RGS19 | regulator of G-protein signaling 19 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF25 | ring finger protein 25 |
| SIRT6 | sirtuin 6 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC38A10 | solute carrier family 38, member 10 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMA4 | glucuronidase, beta pseudogene |
| SNX24 | sorting nexin 24 |
| SYCP2 | synaptonemal complex protein 2 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TMEM2 | transmembrane protein 2 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSPAN5 | tetraspanin 5 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| ULBP2 | UL16 binding protein 2 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VEGFC | vascular endothelial growth factor C |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF219 | zinc finger protein 219 |
| ZNF318 | zinc finger protein 318 |
| ZNF492 | zinc finger protein 492 |
| ZNF7 | zinc finger protein 7 |
| ZNF747 | zinc finger protein 747 |
| ZNF770 | zinc finger protein 770 |