ciprofibrate-3561 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ciprofibrate-3561 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AHSG alpha-2-HS-glycoprotein
ANK1 ankyrin 1, erythrocytic
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
BCL2 B-cell CLL/lymphoma 2
BIN1 bridging integrator 1
C21ORF2 chromosome 21 open reading frame 2
C3 complement component 3
CA5BP1 carbonic anhydrase VB pseudogene 1
CCPG1 cell cycle progression 1
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN6 chloride channel, voltage-sensitive 6
CNGA1 cyclic nucleotide gated channel alpha 1
COL1A1 collagen, type I, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DOPEY2 dopey family member 2
DST dystonin
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
EHBP1L1 EH domain binding protein 1-like 1
EMCN endomucin
ERP44 endoplasmic reticulum protein 44
FABP3 fatty acid binding protein 3, muscle and heart
FAM76A family with sequence similarity 76, member A
FBXO4 F-box protein 4
FGF18 fibroblast growth factor 18
FMOD fibromodulin
GPR21 G protein-coupled receptor 21
GSAP gamma-secretase activating protein
GSPT1 G1 to S phase transition 1
HIST1H4B histone cluster 1, H4b
HLF hepatic leukemia factor
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
ICOSLG inducible T-cell co-stimulator ligand
IDS iduronate 2-sulfatase
IRF2BP1 interferon regulatory factor 2 binding protein 1
KANK1 KN motif and ankyrin repeat domains 1
KLK8 kallikrein-related peptidase 8
LEFTY1 left-right determination factor 1
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MMP24 matrix metallopeptidase 24 (membrane-inserted)
NEUROD1 neuronal differentiation 1
NOVA2 neuro-oncological ventral antigen 2
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRF1 nuclear respiratory factor 1
NXPH3 neurexophilin 3
OCLM oculomedin
PAPOLG poly(A) polymerase gamma
PGK2 phosphoglycerate kinase 2
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCL2 phospholipase C-like 2
POFUT1 protein O-fucosyltransferase 1
POU2F3 POU class 2 homeobox 3
PPARD peroxisome proliferator-activated receptor delta
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRAME preferentially expressed antigen in melanoma
RAB36 RAB36, member RAS oncogene family
RHEB Ras homolog enriched in brain
RNF122 ring finger protein 122
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
S100A11 S100 calcium binding protein A11
S100A8 S100 calcium binding protein A8
SCN1B sodium channel, voltage gated, type I beta subunit
SFRP4 secreted frizzled-related protein 4
SH2D3A SH2 domain containing 3A
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMC4 structural maintenance of chromosomes 4
SPTB spectrin, beta, erythrocytic
STAT2 signal transducer and activator of transcription 2, 113kDa
STMN4 stathmin-like 4
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TBX1 T-box 1
TCP10 t-complex 10
TCP11L1 t-complex 11, testis-specific-like 1
TGM2 transglutaminase 2
THBS3 thrombospondin 3
TMEM63A transmembrane protein 63A
TMLHE trimethyllysine hydroxylase, epsilon
TPMT thiopurine S-methyltransferase
TPP1 tripeptidyl peptidase I
TRIM10 tripartite motif containing 10
VAC14 Vac14 homolog (S. cerevisiae)
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)
YBX3 Y box binding protein 3
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP7A ATPase, Cu++ transporting, alpha polypeptide
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BBC3 BCL2 binding component 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF70 chromosome 17 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
C5ORF45 chromosome 5 open reading frame 45
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBR4 carbonyl reductase 4
CBX4 chromobox homolog 4
CCDC68 coiled-coil domain containing 68
CCNO cyclin O
CD151 CD151 molecule (Raph blood group)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEP97 centrosomal protein 97kDa
CGA glycoprotein hormones, alpha polypeptide
CHST10 carbohydrate sulfotransferase 10
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLCN5 chloride channel, voltage-sensitive 5
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DESI1 desumoylating isopeptidase 1
EMD emerin
FAM204A family with sequence similarity 204, member A
FKBP5 FK506 binding protein 5
FLT4 fms-related tyrosine kinase 4
FUZ fuzzy planar cell polarity protein
GAB2 GRB2-associated binding protein 2
GCHFR GTP cyclohydrolase I feedback regulator
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIPC1 GIPC PDZ domain containing family, member 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GTF2I general transcription factor IIi
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HCAR3 hydroxycarboxylic acid receptor 3
HIRA histone cell cycle regulator
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IL4R interleukin 4 receptor
IREB2 iron-responsive element binding protein 2
IRF2 interferon regulatory factor 2
JUNB jun B proto-oncogene
KAT2A K(lysine) acetyltransferase 2A
KIAA0586 KIAA0586
KIZ kizuna centrosomal protein
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP5 low density lipoprotein receptor-related protein 5
LY6D lymphocyte antigen 6 complex, locus D
MRPL41 mitochondrial ribosomal protein L41
MYL5 myosin, light chain 5, regulatory
NPFFR1 neuropeptide FF receptor 1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
PADI1 peptidyl arginine deiminase, type I
PARPBP PARP1 binding protein
PCDHB3 protocadherin beta 3
PLA2G3 phospholipase A2, group III
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PMCH pro-melanin-concentrating hormone
POR P450 (cytochrome) oxidoreductase
PRPH peripherin
RAB23 RAB23, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RBM42 RNA binding motif protein 42
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SCGB2A2 secretoglobin, family 2A, member 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SKIL SKI-like proto-oncogene
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SUN2 Sad1 and UNC84 domain containing 2
SYTL2 synaptotagmin-like 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TET3 tet methylcytosine dioxygenase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TICAM1 toll-like receptor adaptor molecule 1
TMEM39B transmembrane protein 39B
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TSPYL2 TSPY-like 2
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
VAX2 ventral anterior homeobox 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR4 WD repeat domain 4
WDR76 WD repeat domain 76
ZMAT5 zinc finger, matrin-type 5
ZNF250 zinc finger protein 250
ZNF324 zinc finger protein 324
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862