ciprofibrate-5740 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the ciprofibrate-5740 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADGRB2 adhesion G protein-coupled receptor B2
AGMAT agmatine ureohydrolase (agmatinase)
AMACR alpha-methylacyl-CoA racemase
ARHGAP28 Rho GTPase activating protein 28
ARTN artemin
ATF7 activating transcription factor 7
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BDKRB1 bradykinin receptor B1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C10ORF12 chromosome 10 open reading frame 12
CCL13 chemokine (C-C motif) ligand 13
CCPG1 cell cycle progression 1
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLCA1 chloride channel accessory 1
CLEC4A C-type lectin domain family 4, member A
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COPE coatomer protein complex, subunit epsilon
CROCC ciliary rootlet coiled-coil, rootletin
DNAI2 dynein, axonemal, intermediate chain 2
DUSP2 dual specificity phosphatase 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EMID1 EMI domain containing 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ESRRG estrogen-related receptor gamma
ETV6 ets variant 6
FGF18 fibroblast growth factor 18
FGF5 fibroblast growth factor 5
FLOT1 flotillin 1
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GLE1 GLE1 RNA export mediator
GOLGA8A golgin A8 family, member A
GPM6A glycoprotein M6A
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
H2AFJ H2A histone family, member J
HAMP hepcidin antimicrobial peptide
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSPA1L heat shock 70kDa protein 1-like
IL36A interleukin 36, alpha
IQCK IQ motif containing K
KIAA0319L KIAA0319-like
KIAA1109 KIAA1109
LAMA2 laminin, alpha 2
LIN7B lin-7 homolog B (C. elegans)
LINC00341 long intergenic non-protein coding RNA 341
MAGOH2P mago-nashi homolog 2, pseudogene
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MR1 major histocompatibility complex, class I-related
MTCP1 mature T-cell proliferation 1
NPPA natriuretic peptide A
NUDC nudC nuclear distribution protein
OPCML opioid binding protein/cell adhesion molecule-like
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACS1 phosphofurin acidic cluster sorting protein 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PML promyelocytic leukemia
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PTK2B protein tyrosine kinase 2 beta
RAB26 RAB26, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RGS4 regulator of G-protein signaling 4
RNF6 ring finger protein (C3H2C3 type) 6
RPL35A ribosomal protein L35a
SASH3 SAM and SH3 domain containing 3
SBNO1 strawberry notch homolog 1 (Drosophila)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SOCS3 suppressor of cytokine signaling 3
SOX15 SRY (sex determining region Y)-box 15
SPAG6 sperm associated antigen 6
SPARCL1 SPARC-like 1 (hevin)
SPATA6 spermatogenesis associated 6
SPRED2 sprouty-related, EVH1 domain containing 2
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
TBL1Y transducin (beta)-like 1, Y-linked
TEF thyrotrophic embryonic factor
TFEB transcription factor EB
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TSPAN7 tetraspanin 7
TTLL3 tubulin tyrosine ligase-like family member 3
WT1-AS WT1 antisense RNA
ZBTB3 zinc finger and BTB domain containing 3
ZIC3 Zic family member 3
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALPK1 alpha-kinase 1
ANXA10 annexin A10
APOLD1 apolipoprotein L domain containing 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BIK BCL2-interacting killer (apoptosis-inducing)
BTC betacellulin
C16ORF45 chromosome 16 open reading frame 45
C1QTNF3 C1q and tumor necrosis factor related protein 3
C1R complement component 1, r subcomponent
C7ORF43 chromosome 7 open reading frame 43
CCDC9 coiled-coil domain containing 9
CDON cell adhesion associated, oncogene regulated
CDT1 chromatin licensing and DNA replication factor 1
CENPO centromere protein O
CEP131 centrosomal protein 131kDa
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLDN11 claudin 11
CLDN15 claudin 15
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPED1 cadherin-like and PC-esterase domain containing 1
CRLF1 cytokine receptor-like factor 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DENND2D DENN/MADD domain containing 2D
DPF3 D4, zinc and double PHD fingers, family 3
EIF5A2 eukaryotic translation initiation factor 5A2
FBXL7 F-box and leucine-rich repeat protein 7
FGF13 fibroblast growth factor 13
FGF23 fibroblast growth factor 23
GLCE glucuronic acid epimerase
GLS2 glutaminase 2 (liver, mitochondrial)
GRAMD1C GRAM domain containing 1C
GTF2I general transcription factor IIi
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2AJ histone cluster 1, H2aj
HOXB5 homeobox B5
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INF2 inverted formin, FH2 and WH2 domain containing
IPO8 importin 8
KDM5C lysine (K)-specific demethylase 5C
KLF3 Kruppel-like factor 3 (basic)
KLHL28 kelch-like family member 28
KLHL3 kelch-like family member 3
KRT31 keratin 31, type I
KRT9 keratin 9, type I
LIMS2 LIM and senescent cell antigen-like domains 2
LOC257152 uncharacterized LOC257152
LRP2 low density lipoprotein receptor-related protein 2
LRRK1 leucine-rich repeat kinase 1
LY6G5C lymphocyte antigen 6 complex, locus G5C
MED9 mediator complex subunit 9
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MVD mevalonate (diphospho) decarboxylase
NOL12 nucleolar protein 12
NPY1R neuropeptide Y receptor Y1
NRTN neurturin
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PC pyruvate carboxylase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRAMEF11 PRAME family member 11
RAB3A RAB3A, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RNF122 ring finger protein 122
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCN9A sodium channel, voltage gated, type IX alpha subunit
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIRT6 sirtuin 6
SLC35F6 solute carrier family 35, member F6
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SPATA2L spermatogenesis associated 2-like
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STEAP4 STEAP family member 4
SULT4A1 sulfotransferase family 4A, member 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMCC2 transmembrane and coiled-coil domain family 2
TRAF2 TNF receptor-associated factor 2
TUBA3C tubulin, alpha 3c
TUBB2B tubulin, beta 2B class IIb
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEZT vezatin, adherens junctions transmembrane protein
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZFHX2 zinc finger homeobox 2
ZFHX3 zinc finger homeobox 3
ZNF10 zinc finger protein 10
ZNF215 zinc finger protein 215
ZXDC ZXD family zinc finger C