ciprofibrate-6218 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the ciprofibrate-6218 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ADRBK1 adrenergic, beta, receptor kinase 1
AHDC1 AT hook, DNA binding motif, containing 1
AKR1C1 aldo-keto reductase family 1, member C1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARL15 ADP-ribosylation factor-like 15
ASB1 ankyrin repeat and SOCS box containing 1
ATN1 atrophin 1
CCL27 chemokine (C-C motif) ligand 27
CD44 CD44 molecule (Indian blood group)
CD52 CD52 molecule
CD82 CD82 molecule
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CPT2 carnitine palmitoyltransferase 2
DCN decorin
DENND4A DENN/MADD domain containing 4A
DIAPH2 diaphanous-related formin 2
DRD1 dopamine receptor D1
EFCAB2 EF-hand calcium binding domain 2
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EML2 echinoderm microtubule associated protein like 2
ERAP1 endoplasmic reticulum aminopeptidase 1
FBXL18 F-box and leucine-rich repeat protein 18
FLJ11292
FOXO1 forkhead box O1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GRM8 glutamate receptor, metabotropic 8
GTPBP4 GTP binding protein 4
HIST1H2AJ histone cluster 1, H2aj
HNF1B HNF1 homeobox B
IGSF1 immunoglobulin superfamily, member 1
ING4 inhibitor of growth family, member 4
IRF6 interferon regulatory factor 6
ITGA10 integrin, alpha 10
KRT17 keratin 17, type I
LMNA lamin A/C
LRRC41 leucine rich repeat containing 41
LY6G6C lymphocyte antigen 6 complex, locus G6C
MFAP3L microfibrillar-associated protein 3-like
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTA1 metastasis associated 1
MUC1 mucin 1, cell surface associated
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NPFFR1 neuropeptide FF receptor 1
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OGFR opioid growth factor receptor
OSMR oncostatin M receptor
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLSCR1 phospholipid scramblase 1
PPAP2B phosphatidic acid phosphatase type 2B
PRPH peripherin
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RNF39 ring finger protein 39
RPGR retinitis pigmentosa GTPase regulator
RPS3A ribosomal protein S3A
SBF1 SET binding factor 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SND1-IT1 SND1 intronic transcript 1
SPIDR scaffolding protein involved in DNA repair
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SSX1 synovial sarcoma, X breakpoint 1
SUGP1 SURP and G patch domain containing 1
SYNGR1 synaptogyrin 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TGM2 transglutaminase 2
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TLE2 transducin-like enhancer of split 2
TM2D1 TM2 domain containing 1
TMPO thymopoietin
TOR1AIP1 torsin A interacting protein 1
TRAK1 trafficking protein, kinesin binding 1
TRIM14 tripartite motif containing 14
TRO trophinin
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC30A tetratricopeptide repeat domain 30A
TTC33 tetratricopeptide repeat domain 33
TUBA3C tubulin, alpha 3c
UBE3A ubiquitin protein ligase E3A
VIPR1 vasoactive intestinal peptide receptor 1
VN1R1 vomeronasal 1 receptor 1
VPRBP Vpr (HIV-1) binding protein
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZDHHC17 zinc finger, DHHC-type containing 17
ZFPL1 zinc finger protein-like 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF747 zinc finger protein 747
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM15 ADAM metallopeptidase domain 15
ADCK3 aarF domain containing kinase 3
ADRA2C adrenoceptor alpha 2C
AKAP12 A kinase (PRKA) anchor protein 12
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
AXIN1 axin 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BEX4 brain expressed, X-linked 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C19ORF40 chromosome 19 open reading frame 40
C2ORF44 chromosome 2 open reading frame 44
CAMTA2 calmodulin binding transcription activator 2
CAPN15 calpain 15
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CISH cytokine inducible SH2-containing protein
COCH cochlin
DCAF8 DDB1 and CUL4 associated factor 8
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNASE1L1 deoxyribonuclease I-like 1
E2F1 E2F transcription factor 1
EGLN3 egl-9 family hypoxia-inducible factor 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAM86C1 family with sequence similarity 86, member C1
FBXO22 F-box protein 22
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GHR growth hormone receptor
GLI3 GLI family zinc finger 3
GNL1 guanine nucleotide binding protein-like 1
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2BC histone cluster 1, H2bc
HOOK1 hook microtubule-tethering protein 1
ICK intestinal cell (MAK-like) kinase
INPPL1 inositol polyphosphate phosphatase-like 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD20 potassium channel tetramerization domain containing 20
KIAA0894 KIAA0894 protein
KLHL36 kelch-like family member 36
KRBOX4 KRAB box domain containing 4
KRT8P12 keratin 8 pseudogene 12
LOC730101 uncharacterized LOC730101
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC20 leucine rich repeat containing 20
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL2B methyltransferase like 2B
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MMP9 matrix metallopeptidase 9
MRPL44 mitochondrial ribosomal protein L44
MVD mevalonate (diphospho) decarboxylase
MXD3 MAX dimerization protein 3
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
NLK nemo-like kinase
ONECUT2 one cut homeobox 2
PARD6A par-6 family cell polarity regulator alpha
PARP16 poly (ADP-ribose) polymerase family, member 16
PCSK7 proprotein convertase subtilisin/kexin type 7
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLD3 phospholipase D family, member 3
PRR3 proline rich 3
PRR7 proline rich 7 (synaptic)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SKA1 spindle and kinetochore associated complex subunit 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SNUPN snurportin 1
SOX12 SRY (sex determining region Y)-box 12
SPATA7 spermatogenesis associated 7
STARD13 StAR-related lipid transfer (START) domain containing 13
STX5 syntaxin 5
STXBP1 syntaxin binding protein 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUSD6 sushi domain containing 6
TMEM180 transmembrane protein 180
TRAF5 TNF receptor-associated factor 5
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRIM66 tripartite motif containing 66
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TWF2 twinfilin actin binding protein 2
UBXN6 UBX domain protein 6
USP18 ubiquitin specific peptidase 18
VAV1 vav 1 guanine nucleotide exchange factor
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF211 zinc finger protein 211
ZNF276 zinc finger protein 276
ZNF8 zinc finger protein 8