ciprofloxacin-1522 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the ciprofloxacin-1522 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKT2 v-akt murine thymoma viral oncogene homolog 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGAP1 Rho GTPase activating protein 1
ASB1 ankyrin repeat and SOCS box containing 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAHCC1 BAH domain and coiled-coil containing 1
C11ORF30 chromosome 11 open reading frame 30
C1QL1 complement component 1, q subcomponent-like 1
CA5B carbonic anhydrase VB, mitochondrial
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CATSPERB catsper channel auxiliary subunit beta
CCL5 chemokine (C-C motif) ligand 5
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDC25A cell division cycle 25A
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DCAKD dephospho-CoA kinase domain containing
DLC1 DLC1 Rho GTPase activating protein
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DOCK10 dedicator of cytokinesis 10
DRP2 dystrophin related protein 2
EFR3B EFR3 homolog B (S. cerevisiae)
EGFR epidermal growth factor receptor
ELP6 elongator acetyltransferase complex subunit 6
EMID1 EMI domain containing 1
EPS8L1 EPS8-like 1
ERCC2 excision repair cross-complementation group 2
FLJ11292
FLOT1 flotillin 1
FRS3 fibroblast growth factor receptor substrate 3
GDNF glial cell derived neurotrophic factor
GHRH growth hormone releasing hormone
GPR1 G protein-coupled receptor 1
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HPS1 Hermansky-Pudlak syndrome 1
IGF1R insulin-like growth factor 1 receptor
ISG20 interferon stimulated exonuclease gene 20kDa
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KLF12 Kruppel-like factor 12
LINC00312 long intergenic non-protein coding RNA 312
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAOA monoamine oxidase A
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MBNL2 muscleblind-like splicing regulator 2
MGC12488
MPO myeloperoxidase
MSL3 male-specific lethal 3 homolog (Drosophila)
MTCP1 mature T-cell proliferation 1
MYL10 myosin, light chain 10, regulatory
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NUMA1 nuclear mitotic apparatus protein 1
OR7E24 olfactory receptor, family 7, subfamily E, member 24
OVGP1 oviductal glycoprotein 1, 120kDa
PCDHB6 protocadherin beta 6
PCDHB8 protocadherin beta 8
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PER2 period circadian clock 2
PFDN6 prefoldin subunit 6
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PMEL premelanosome protein
PODNL1 podocan-like 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PVR poliovirus receptor
RAD52 RAD52 homolog (S. cerevisiae)
RFPL3 ret finger protein-like 3
RNF126P1 ring finger protein 126 pseudogene 1
RPL7 ribosomal protein L7
RUNX1 runt-related transcription factor 1
RYR1 ryanodine receptor 1 (skeletal)
SCAND2P SCAN domain containing 2 pseudogene
SCAPER S-phase cyclin A-associated protein in the ER
SEC24D SEC24 family member D
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC45A2 solute carrier family 45, member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMG7-AS1 SMG7 antisense RNA 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SYMPK symplekin
SYNJ2 synaptojanin 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TCF4 transcription factor 4
TJAP1 tight junction associated protein 1 (peripheral)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM36 tripartite motif containing 36
VAC14 Vac14 homolog (S. cerevisiae)
VAV2 vav 2 guanine nucleotide exchange factor
VSNL1 visinin-like 1
ZNF37BP zinc finger protein 37B, pseudogene
ZNF783 zinc finger family member 783
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACSL4 acyl-CoA synthetase long-chain family member 4
ADAM15 ADAM metallopeptidase domain 15
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BRPF1 bromodomain and PHD finger containing, 1
C10ORF88 chromosome 10 open reading frame 88
C17ORF80 chromosome 17 open reading frame 80
C5 complement component 5
C5ORF45 chromosome 5 open reading frame 45
CAPG capping protein (actin filament), gelsolin-like
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CD302 CD302 molecule
CDKL3 cyclin-dependent kinase-like 3
CHKB choline kinase beta
CLEC16A C-type lectin domain family 16, member A
COPS7B COP9 signalosome subunit 7B
CRELD1 cysteine-rich with EGF-like domains 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
EFCAB2 EF-hand calcium binding domain 2
ERCC5 excision repair cross-complementation group 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM86C1 family with sequence similarity 86, member C1
FBXO31 F-box protein 31
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBP10 FK506 binding protein 10, 65 kDa
FPGS folylpolyglutamate synthase
GAMT guanidinoacetate N-methyltransferase
GCA grancalcin, EF-hand calcium binding protein
GFOD1 glucose-fructose oxidoreductase domain containing 1
GID4 GID complex subunit 4
GPR87 G protein-coupled receptor 87
GPRASP1 G protein-coupled receptor associated sorting protein 1
GTF2I general transcription factor IIi
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HAUS6 HAUS augmin-like complex, subunit 6
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFI35 interferon-induced protein 35
IMPACT impact RWD domain protein
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF1 interferon regulatory factor 1
JADE3 jade family PHD finger 3
KDM5C lysine (K)-specific demethylase 5C
KLHL25 kelch-like family member 25
KRT13 keratin 13, type I
MAP9 microtubule-associated protein 9
MB myoglobin
MED24 mediator complex subunit 24
MOGS mannosyl-oligosaccharide glucosidase
MON1B MON1 secretory trafficking family member B
MT1H metallothionein 1H
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
MYLIP myosin regulatory light chain interacting protein
NKRF NFKB repressing factor
NLK nemo-like kinase
NRGN neurogranin (protein kinase C substrate, RC3)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHB3 protocadherin beta 3
PCNXL4 pecanex-like 4 (Drosophila)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
RAB30 RAB30, member RAS oncogene family
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SHARPIN SHANK-associated RH domain interactor
SLC16A6 solute carrier family 16, member 6
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SNORA21 small nucleolar RNA, H/ACA box 21
SOWAHC sosondowah ankyrin repeat domain family member C
STK16 serine/threonine kinase 16
TBC1D17 TBC1 domain family, member 17
TBX19 T-box 19
TFF2 trefoil factor 2
TMEM180 transmembrane protein 180
TMEM260 transmembrane protein 260
TNS2 tensin 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
USP20 ubiquitin specific peptidase 20
VAX2 ventral anterior homeobox 2
WDR25 WD repeat domain 25
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF211 zinc finger protein 211
ZNF276 zinc finger protein 276
ZNF665 zinc finger protein 665
ZNF8 zinc finger protein 8