| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the ciprofloxacin-1939 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD5 | abhydrolase domain containing 5 |
| ACACA | acetyl-CoA carboxylase alpha |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| AREG | amphiregulin |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ARSJ | arylsulfatase family, member J |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| C17ORF62 | chromosome 17 open reading frame 62 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CHD3 | chromodomain helicase DNA binding protein 3 |
| CLIP1 | CAP-GLY domain containing linker protein 1 |
| CPOX | coproporphyrinogen oxidase |
| CTBS | chitobiase, di-N-acetyl- |
| CUL2 | cullin 2 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DCAF8 | DDB1 and CUL4 associated factor 8 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DOCK10 | dedicator of cytokinesis 10 |
| DTNA | dystrobrevin, alpha |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNB3 | ephrin-B3 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J |
| EIF4ENIF1 | eukaryotic translation initiation factor 4E nuclear import factor 1 |
| EPHB2 | EPH receptor B2 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM63A | family with sequence similarity 63, member A |
| FBXO31 | F-box protein 31 |
| FHL3 | four and a half LIM domains 3 |
| GALR3 | galanin receptor 3 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GSK3A | glycogen synthase kinase 3 alpha |
| H2AFY2 | H2A histone family, member Y2 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KIAA0141 | KIAA0141 |
| KIAA0232 | KIAA0232 |
| KLHL24 | kelch-like family member 24 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT86 | keratin 86, type II |
| LIN7C | lin-7 homolog C (C. elegans) |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAOA | monoamine oxidase A |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit |
| NCKAP1 | NCK-associated protein 1 |
| NXN | nucleoredoxin |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OXR1 | oxidation resistance 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PF4 | platelet factor 4 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha |
| PRR3 | proline rich 3 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| SEC23B | Sec23 homolog B (S. cerevisiae) |
| SERBP1 | SERPINE1 mRNA binding protein 1 |
| SMC3 | structural maintenance of chromosomes 3 |
| SOCS6 | suppressor of cytokine signaling 6 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRSF10 | serine/arginine-rich splicing factor 10 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STXBP3 | syntaxin binding protein 3 |
| TBCCD1 | TBCC domain containing 1 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) |
| TMED7 | transmembrane emp24 protein transport domain containing 7 |
| TMEM135 | transmembrane protein 135 |
| TMPO | thymopoietin |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIP6 | thyroid hormone receptor interactor 6 |
| TSC22D1 | TSC22 domain family, member 1 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 |
| UBFD1 | ubiquitin family domain containing 1 |
| UBL3 | ubiquitin-like 3 |
| WEE1 | WEE1 G2 checkpoint kinase |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 |
| YLPM1 | YLP motif containing 1 |
| ZNF337 | zinc finger protein 337 |
| ZNF426 | zinc finger protein 426 |
| ZNF609 | zinc finger protein 609 |
| ZNF652 | zinc finger protein 652 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABT1 | activator of basal transcription 1 |
| AES | amino-terminal enhancer of split |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| BANF1 | barrier to autointegration factor 1 |
| BMS1 | BMS1 ribosome biogenesis factor |
| BNC2 | basonuclin 2 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CISH | cytokine inducible SH2-containing protein |
| CLDN4 | claudin 4 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CLSTN1 | calsyntenin 1 |
| CTAGE9 | CTAGE family, member 9 |
| CXORF40B | chromosome X open reading frame 40B |
| CYB5R4 | cytochrome b5 reductase 4 |
| DCP1A | decapping mRNA 1A |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EVPL | envoplakin |
| FBXO34 | F-box protein 34 |
| FKBPL | FK506 binding protein like |
| FOXD1 | forkhead box D1 |
| FPGS | folylpolyglutamate synthase |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GOLGA8B | golgin A8 family, member B |
| GPX2 | glutathione peroxidase 2 |
| GTF2E1 | general transcription factor IIE, polypeptide 1, alpha 56kDa |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HOOK2 | hook microtubule-tethering protein 2 |
| HS1BP3 | HCLS1 binding protein 3 |
| KIF3B | kinesin family member 3B |
| LAMA5 | laminin, alpha 5 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MITF | microphthalmia-associated transcription factor |
| MPG | N-methylpurine-DNA glycosylase |
| MPV17 | MpV17 mitochondrial inner membrane protein |
| MT2A | metallothionein 2A |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NDUFV1 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NRBP1 | nuclear receptor binding protein 1 |
| NVL | nuclear VCP-like |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PADI1 | peptidyl arginine deiminase, type I |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCTP | phosphatidylcholine transfer protein |
| PIH1D1 | PIH1 domain containing 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PITPNB | phosphatidylinositol transfer protein, beta |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PMM1 | phosphomannomutase 1 |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RPL34 | ribosomal protein L34 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SELENBP1 | selenium binding protein 1 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SMAGP | small cell adhesion glycoprotein |
| SNTA1 | syntrophin, alpha 1 |
| SPX | spexin hormone |
| SRP54 | signal recognition particle 54kDa |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TBK1 | TANK-binding kinase 1 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM242 | transmembrane protein 242 |
| TMEM62 | transmembrane protein 62 |
| TMEM74B | transmembrane protein 74B |
| TOLLIP | toll interacting protein |
| TP53I3 | tumor protein p53 inducible protein 3 |
| TPCN1 | two pore segment channel 1 |
| TRAIP | TRAF interacting protein |
| TSPAN32 | tetraspanin 32 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UBXN2B | UBX domain protein 2B |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| VASP | vasodilator-stimulated phosphoprotein |
| WDR73 | WD repeat domain 73 |
| ZNF358 | zinc finger protein 358 |
| ZNF580 | zinc finger protein 580 |
| ZNF611 | zinc finger protein 611 |
