| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ciprofloxacin-2022 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ACAN | aggrecan |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| ADAM8 | ADAM metallopeptidase domain 8 |
| AHI1 | Abelson helper integration site 1 |
| ARRB2 | arrestin, beta 2 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATG9A | autophagy related 9A |
| BMP15 | bone morphogenetic protein 15 |
| C2CD2L | C2CD2-like |
| C3 | complement component 3 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
| CEP68 | centrosomal protein 68kDa |
| CHKA | choline kinase alpha |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CMC4 | C-x(9)-C motif containing 4 |
| COG5 | component of oligomeric golgi complex 5 |
| COL4A2 | collagen, type IV, alpha 2 |
| CSN2 | casein beta |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 |
| DEDD | death effector domain containing |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ELMO2 | engulfment and cell motility 2 |
| EML2 | echinoderm microtubule associated protein like 2 |
| FAM188A | family with sequence similarity 188, member A |
| FAS | Fas cell surface death receptor |
| FYB | FYN binding protein |
| GDF3 | growth differentiation factor 3 |
| GDF5 | growth differentiation factor 5 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| HBB | hemoglobin, beta |
| HIRA | histone cell cycle regulator |
| HTT | huntingtin |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| KIFC1 | kinesin family member C1 |
| KIZ | kizuna centrosomal protein |
| LIMD2 | LIM domain containing 2 |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| LTB4R | leukotriene B4 receptor |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAGED2 | melanoma antigen family D2 |
| MAML3 | mastermind-like 3 (Drosophila) |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) |
| MECP2 | methyl CpG binding protein 2 |
| MED15 | mediator complex subunit 15 |
| MED7 | mediator complex subunit 7 |
| MSH3 | mutS homolog 3 |
| NBEAL2 | neurobeachin-like 2 |
| NCOA3 | nuclear receptor coactivator 3 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PARD3 | par-3 family cell polarity regulator |
| PAX1 | paired box 1 |
| PCTP | phosphatidylcholine transfer protein |
| PDE8A | phosphodiesterase 8A |
| PHTF1 | putative homeodomain transcription factor 1 |
| PIDD1 | p53-induced death domain protein 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 |
| PTCRA | pre T-cell antigen receptor alpha |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RARA | retinoic acid receptor, alpha |
| RBBP5 | retinoblastoma binding protein 5 |
| RBM34 | RNA binding motif protein 34 |
| RBM48 | RNA binding motif protein 48 |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIK2 | salt-inducible kinase 2 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOD3 | superoxide dismutase 3, extracellular |
| SSH3 | slingshot protein phosphatase 3 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| STAB2 | stabilin 2 |
| SUPT4H1 | suppressor of Ty 4 homolog 1 (S. cerevisiae) |
| TBC1D29 | TBC1 domain family, member 29 |
| TESK1 | testis-specific kinase 1 |
| TGM5 | transglutaminase 5 |
| THY1 | Thy-1 cell surface antigen |
| TM2D1 | TM2 domain containing 1 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| TSPYL2 | TSPY-like 2 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| TULP3 | tubby like protein 3 |
| UBE3A | ubiquitin protein ligase E3A |
| UBOX5 | U-box domain containing 5 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| WDR48 | WD repeat domain 48 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTL6A | actin-like 6A |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| ATAD2 | ATPase family, AAA domain containing 2 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BCORL1 | BCL6 corepressor-like 1 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| CTSK | cathepsin K |
| DBF4B | DBF4 zinc finger B |
| DIXDC1 | DIX domain containing 1 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
| ERBB2IP | erbb2 interacting protein |
| FAM50B | family with sequence similarity 50, member B |
| FAM63A | family with sequence similarity 63, member A |
| FANCC | Fanconi anemia, complementation group C |
| FANCF | Fanconi anemia, complementation group F |
| FBXO5 | F-box protein 5 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GRM6 | glutamate receptor, metabotropic 6 |
| GRPR | gastrin-releasing peptide receptor |
| GSTM5 | glutathione S-transferase mu 5 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HINFP | histone H4 transcription factor |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HSPA4L | heat shock 70kDa protein 4-like |
| IL4R | interleukin 4 receptor |
| IMPACT | impact RWD domain protein |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KIFAP3 | kinesin-associated protein 3 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC642236 | FSHD region gene 1 pseudogene |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| METTL21B | methyltransferase like 21B |
| METTL22 | methyltransferase like 22 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NPPA | natriuretic peptide A |
| NRBP1 | nuclear receptor binding protein 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NTAN1 | N-terminal asparagine amidase |
| OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OSTF1 | osteoclast stimulating factor 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PDZD8 | PDZ domain containing 8 |
| PGRMC2 | progesterone receptor membrane component 2 |
| PLCD1 | phospholipase C, delta 1 |
| PODNL1 | podocan-like 1 |
| PRDM13 | PR domain containing 13 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RHOH | ras homolog family member H |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SETD1B | SET domain containing 1B |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SMAP1 | small ArfGAP 1 |
| SNX10 | sorting nexin 10 |
| SP140L | SP140 nuclear body protein-like |
| SPON2 | spondin 2, extracellular matrix protein |
| STXBP3 | syntaxin binding protein 3 |
| TBCCD1 | TBCC domain containing 1 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) |
| TMEM14A | transmembrane protein 14A |
| TMPRSS6 | transmembrane protease, serine 6 |
| TSPYL4 | TSPY-like 4 |
| TTF2 | transcription termination factor, RNA polymerase II |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| TXNDC15 | thioredoxin domain containing 15 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VASP | vasodilator-stimulated phosphoprotein |
| WDR76 | WD repeat domain 76 |
| YEATS4 | YEATS domain containing 4 |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZFAND1 | zinc finger, AN1-type domain 1 |
| ZNF32 | zinc finger protein 32 |
| ZNF443 | zinc finger protein 443 |
| ZNF529 | zinc finger protein 529 |
| ZNF671 | zinc finger protein 671 |
| ZNF804A | zinc finger protein 804A |
