ciprofloxacin-5299 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ciprofloxacin-5299 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN1 actinin, alpha 1
ACVR1B activin A receptor, type IB
AKIP1 A kinase (PRKA) interacting protein 1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASB1 ankyrin repeat and SOCS box containing 1
AXIN1 axin 1
BAIAP2 BAI1-associated protein 2
BCOR BCL6 corepressor
BIN1 bridging integrator 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CABIN1 calcineurin binding protein 1
CCDC93 coiled-coil domain containing 93
CD44 CD44 molecule (Indian blood group)
CD82 CD82 molecule
CDYL chromodomain protein, Y-like
CLCN7 chloride channel, voltage-sensitive 7
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DPH5 diphthamide biosynthesis 5
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EML3 echinoderm microtubule associated protein like 3
EPHB3 EPH receptor B3
ERN2 endoplasmic reticulum to nucleus signaling 2
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FAM214B family with sequence similarity 214, member B
FERMT2 fermitin family member 2
FKBP10 FK506 binding protein 10, 65 kDa
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GREB1 growth regulation by estrogen in breast cancer 1
H2AFX H2A histone family, member X
HLA-J major histocompatibility complex, class I, J (pseudogene)
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HPN hepsin
HSF1 heat shock transcription factor 1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT140 intraflagellar transport 140
IL1R1 interleukin 1 receptor, type I
IP6K1 inositol hexakisphosphate kinase 1
KAT6A K(lysine) acetyltransferase 6A
KDM2A lysine (K)-specific demethylase 2A
KLF9 Kruppel-like factor 9
KLK5 kallikrein-related peptidase 5
LIN7A lin-7 homolog A (C. elegans)
LIN7C lin-7 homolog C (C. elegans)
MAPK3 mitogen-activated protein kinase 3
MFAP2 microfibrillar-associated protein 2
MOCS1 molybdenum cofactor synthesis 1
MTA1 metastasis associated 1
MVD mevalonate (diphospho) decarboxylase
MXD3 MAX dimerization protein 3
NCAPH2 non-SMC condensin II complex, subunit H2
NCKAP1 NCK-associated protein 1
NEK3 NIMA-related kinase 3
NME5 NME/NM23 family member 5
NMT1 N-myristoyltransferase 1
NOL12 nucleolar protein 12
NR2F1 nuclear receptor subfamily 2, group F, member 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUMA1 nuclear mitotic apparatus protein 1
OSBPL2 oxysterol binding protein-like 2
PAIP2B poly(A) binding protein interacting protein 2B
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDCL phosducin-like
PDGFA platelet-derived growth factor alpha polypeptide
PEX11A peroxisomal biogenesis factor 11 alpha
PFDN6 prefoldin subunit 6
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RNF121 ring finger protein 121
RPGR retinitis pigmentosa GTPase regulator
RPH3AL rabphilin 3A-like (without C2 domains)
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTN2 reticulon 2
S100A4 S100 calcium binding protein A4
SETD8 SET domain containing (lysine methyltransferase) 8
SFRP4 secreted frizzled-related protein 4
SLC12A8 solute carrier family 12, member 8
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SREBF2 sterol regulatory element binding transcription factor 2
STXBP6 syntaxin binding protein 6 (amisyn)
TAPBP TAP binding protein (tapasin)
THOP1 thimet oligopeptidase 1
TLE2 transducin-like enhancer of split 2
TRIM21 tripartite motif containing 21
TRIM23 tripartite motif containing 23
YLPM1 YLP motif containing 1
ZBTB6 zinc finger and BTB domain containing 6
ZHX3 zinc fingers and homeoboxes 3
ZMYND8 zinc finger, MYND-type containing 8
ZNF75D zinc finger protein 75D
ZNF79 zinc finger protein 79
ZNF804A zinc finger protein 804A
ZYX zyxin

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADGRE5 adhesion G protein-coupled receptor E5
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
APOD apolipoprotein D
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG4A autophagy related 4A, cysteine peptidase
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAGE B melanoma antigen
BBC3 BCL2 binding component 3
BIK BCL2-interacting killer (apoptosis-inducing)
BPGM 2,3-bisphosphoglycerate mutase
BTF3P12 basic transcription factor 3 pseudogene 12
C16ORF59 chromosome 16 open reading frame 59
C1ORF35 chromosome 1 open reading frame 35
CCNL2 cyclin L2
CCNT1 cyclin T1
CDKL3 cyclin-dependent kinase-like 3
CHST10 carbohydrate sulfotransferase 10
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLDN15 claudin 15
DDB1 damage-specific DNA binding protein 1, 127kDa
DDIT3 DNA-damage-inducible transcript 3
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ERO1L ERO1-like (S. cerevisiae)
FBRS fibrosin
GAB2 GRB2-associated binding protein 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALT galactose-1-phosphate uridylyltransferase
GAR1 GAR1 ribonucleoprotein
GLTSCR1 glioma tumor suppressor candidate region gene 1
GOLGA3 golgin A3
GPRASP1 G protein-coupled receptor associated sorting protein 1
HIST1H1D histone cluster 1, H1d
HMGB3P1 high mobility group box 3 pseudogene 1
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
IFI6 interferon, alpha-inducible protein 6
ISG15 ISG15 ubiquitin-like modifier
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
LAMA3 laminin, alpha 3
LAMB2 laminin, beta 2 (laminin S)
LINC00115 long intergenic non-protein coding RNA 115
LINS lines homolog (Drosophila)
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
MANBA mannosidase, beta A, lysosomal
MPI mannose phosphate isomerase
MTCL1 microtubule crosslinking factor 1
MTMR12 myotubularin related protein 12
NARFL nuclear prelamin A recognition factor-like
NECAP2 NECAP endocytosis associated 2
NES nestin
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OSMR oncostatin M receptor
P3H1 prolyl 3-hydroxylase 1
PADI2 peptidyl arginine deiminase, type II
PGP phosphoglycolate phosphatase
PHKG2 phosphorylase kinase, gamma 2 (testis)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PYCRL pyrroline-5-carboxylate reductase-like
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RFTN1 raftlin, lipid raft linker 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RGS17 regulator of G-protein signaling 17
RIBC2 RIB43A domain with coiled-coils 2
RNF31 ring finger protein 31
SHARPIN SHANK-associated RH domain interactor
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC46A3 solute carrier family 46, member 3
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SND1-IT1 SND1 intronic transcript 1
SQRDL sulfide quinone reductase-like (yeast)
STAG3 stromal antigen 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TESK2 testis-specific kinase 2
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM131 transmembrane protein 131
TMEM184C transmembrane protein 184C
TNRC6B trinucleotide repeat containing 6B
TRIM52 tripartite motif containing 52
TSPAN1 tetraspanin 1
TSPYL2 TSPY-like 2
TSSC4 tumor suppressing subtransferable candidate 4
TUBA3C tubulin, alpha 3c
TWF2 twinfilin actin binding protein 2
USP20 ubiquitin specific peptidase 20
WDR46 WD repeat domain 46
XAB2 XPA binding protein 2
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YEATS2 YEATS domain containing 2
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF14 zinc finger protein 14
ZNF184 zinc finger protein 184
ZNF492 zinc finger protein 492
ZNF768 zinc finger protein 768