cisapride-2443 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the cisapride-2443 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADCY9 adenylate cyclase 9
AGGF1 angiogenic factor with G patch and FHA domains 1
AKAP8L A kinase (PRKA) anchor protein 8-like
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
AURKA aurora kinase A
BTD biotinidase
BTN2A2 butyrophilin, subfamily 2, member A2
CAPN10 calpain 10
CCDC106 coiled-coil domain containing 106
CCDC57 coiled-coil domain containing 57
CCSER2 coiled-coil serine-rich protein 2
CD6 CD6 molecule
CLEC3B C-type lectin domain family 3, member B
COX11 COX11 cytochrome c oxidase copper chaperone
CREBZF CREB/ATF bZIP transcription factor
CTNND2 catenin (cadherin-associated protein), delta 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DMC1 DNA meiotic recombinase 1
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EML2 echinoderm microtubule associated protein like 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPS8L3 EPS8-like 3
ESRRA estrogen-related receptor alpha
FAM64A family with sequence similarity 64, member A
FCAR Fc fragment of IgA receptor
FCMR Fc fragment of IgM receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSTA3 glutathione S-transferase alpha 3
HCFC1 host cell factor C1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HRH4 histamine receptor H4
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
IGLJ3 immunoglobulin lambda joining 3
ISL1 ISL LIM homeobox 1
JPH3 junctophilin 3
KLHL25 kelch-like family member 25
LEFTY1 left-right determination factor 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LTB4R leukotriene B4 receptor
MAPK7 mitogen-activated protein kinase 7
MFAP3 microfibrillar-associated protein 3
MNMIP1 manchette microtubule inner protein 1
NELL2 NEL-like 2 (chicken)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRDE2 NRDE-2, necessary for RNA interference, domain containing
PAX1 paired box 1
PDE4D phosphodiesterase 4D, cAMP-specific
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLK4 polo-like kinase 4
PRB4 proline-rich protein BstNI subfamily 4
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKG2 protein kinase, cGMP-dependent, type II
PRPF18 pre-mRNA processing factor 18
PTK2B protein tyrosine kinase 2 beta
PTTG2 pituitary tumor-transforming 2
RAB6A RAB6A, member RAS oncogene family
RERE arginine-glutamic acid dipeptide (RE) repeats
RIBC2 RIB43A domain with coiled-coils 2
RIMS1 regulating synaptic membrane exocytosis 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A13 S100 calcium binding protein A13
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SNX13 sorting nexin 13
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STX16 syntaxin 16
SUGP1 SURP and G patch domain containing 1
TADA2A transcriptional adaptor 2A
TAPT1 transmembrane anterior posterior transformation 1
TAS2R1 taste receptor, type 2, member 1
TCP11L1 t-complex 11, testis-specific-like 1
THAP9 THAP domain containing 9
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNPO2 transportin 2
TRA T cell receptor alpha locus
TRD T cell receptor delta locus
TRGV5 T cell receptor gamma variable 5
TSC22D3 TSC22 domain family, member 3
TSPAN4 tetraspanin 4
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WWC1 WW and C2 domain containing 1
ZCCHC11 zinc finger, CCHC domain containing 11
ZFHX4 zinc finger homeobox 4

decreased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BIK BCL2-interacting killer (apoptosis-inducing)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSPRY B-box and SPRY domain containing
C1ORF159 chromosome 1 open reading frame 159
C21ORF91 chromosome 21 open reading frame 91
CAMKMT calmodulin-lysine N-methyltransferase
CCDC71 coiled-coil domain containing 71
CD101 CD101 molecule
CDKL3 cyclin-dependent kinase-like 3
CHPF chondroitin polymerizing factor
CLCN2 chloride channel, voltage-sensitive 2
COL15A1 collagen, type XV, alpha 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COQ6 coenzyme Q6 monooxygenase
CRY2 cryptochrome circadian clock 2
CTC1 CTS telomere maintenance complex component 1
CXCR2 chemokine (C-X-C motif) receptor 2
DCAF13 DDB1 and CUL4 associated factor 13
DDN dendrin
DGKG diacylglycerol kinase, gamma 90kDa
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EMID1 EMI domain containing 1
FAM127B family with sequence similarity 127, member B
FBXO46 F-box protein 46
FGL1 fibrinogen-like 1
FGL2 fibrinogen-like 2
FNBP1L formin binding protein 1-like
GALK1 galactokinase 1
GIPC1 GIPC PDZ domain containing family, member 1
GMPPA GDP-mannose pyrophosphorylase A
GPX2 glutathione peroxidase 2
GTF2IRD1 GTF2I repeat domain containing 1
HAMP hepcidin antimicrobial peptide
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HYAL3 hyaluronoglucosaminidase 3
IFI6 interferon, alpha-inducible protein 6
IL2 interleukin 2
INO80D INO80 complex subunit D
IRS1 insulin receptor substrate 1
ITGB7 integrin, beta 7
KCTD2 potassium channel tetramerization domain containing 2
KIAA0319L KIAA0319-like
KLHL36 kelch-like family member 36
LOC157562 uncharacterized LOC157562
LOC257152 uncharacterized LOC257152
LPAR6 lysophosphatidic acid receptor 6
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LY6E lymphocyte antigen 6 complex, locus E
METRN meteorin, glial cell differentiation regulator
MPZ myelin protein zero
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYBPH myosin binding protein H
NARFL nuclear prelamin A recognition factor-like
NINJ2 ninjurin 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OXCT2 3-oxoacid CoA transferase 2
PDGFD platelet derived growth factor D
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEX13 peroxisomal biogenesis factor 13
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHC1 polyhomeotic homolog 1 (Drosophila)
PITX2 paired-like homeodomain 2
PTDSS2 phosphatidylserine synthase 2
PWAR5 Prader Willi/Angelman region RNA 5
QPCTL glutaminyl-peptide cyclotransferase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RAB17 RAB17, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RNF2 ring finger protein 2
RRAS related RAS viral (r-ras) oncogene homolog
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMYD5 SMYD family member 5
SNAI1 snail family zinc finger 1
STK16 serine/threonine kinase 16
STX1A syntaxin 1A (brain)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAGLN transgelin
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM180 transmembrane protein 180
TTC30A tetratricopeptide repeat domain 30A
USP20 ubiquitin specific peptidase 20
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
XAB2 XPA binding protein 2
ZBTB25 zinc finger and BTB domain containing 25
ZBTB44 zinc finger and BTB domain containing 44
ZNF35 zinc finger protein 35
ZNF43 zinc finger protein 43
ZNF580 zinc finger protein 580