cisapride-3305 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the cisapride-3305 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ADAM12 ADAM metallopeptidase domain 12
ADAP2 ArfGAP with dual PH domains 2
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
AQP3 aquaporin 3 (Gill blood group)
ARHGAP4 Rho GTPase activating protein 4
ARHGAP44 Rho GTPase activating protein 44
ART1 ADP-ribosyltransferase 1
ARTN artemin
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATXN2L ataxin 2-like
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BMP1 bone morphogenetic protein 1
BTG3 BTG family, member 3
C10ORF12 chromosome 10 open reading frame 12
C17ORF53 chromosome 17 open reading frame 53
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CD3D CD3d molecule, delta (CD3-TCR complex)
CD8A CD8a molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDRT1 CMT1A duplicated region transcript 1
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
DAPK3 death-associated protein kinase 3
DBF4B DBF4 zinc finger B
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
FANCA Fanconi anemia, complementation group A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGF18 fibroblast growth factor 18
FMO5 flavin containing monooxygenase 5
FN1 fibronectin 1
FOXN3 forkhead box N3
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GGT1 gamma-glutamyltransferase 1
GM2A GM2 ganglioside activator
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPC1 glypican 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRIK5 glutamate receptor, ionotropic, kainate 5
GRM1 glutamate receptor, metabotropic 1
GSTP1 glutathione S-transferase pi 1
HCAR3 hydroxycarboxylic acid receptor 3
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H2BN histone cluster 1, H2bn
HIST1H4A histone cluster 1, H4a
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HN1L hematological and neurological expressed 1-like
HOXC8 homeobox C8
HRH3 histamine receptor H3
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAKMIP2 janus kinase and microtubule interacting protein 2
KLF3 Kruppel-like factor 3 (basic)
KLHL25 kelch-like family member 25
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAGEA5 melanoma antigen family A5
MBP myelin basic protein
MDM4 MDM4, p53 regulator
MEGF6 multiple EGF-like-domains 6
METTL5 methyltransferase like 5
MR1 major histocompatibility complex, class I-related
MRPS12 mitochondrial ribosomal protein S12
MYL10 myosin, light chain 10, regulatory
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NBL1 neuroblastoma 1, DAN family BMP antagonist
NUP188 nucleoporin 188kDa
PDCD2 programmed cell death 2
PDE4DIP phosphodiesterase 4D interacting protein
PHOX2A paired-like homeobox 2a
QKI QKI, KH domain containing, RNA binding
RAD54L2 RAD54-like 2 (S. cerevisiae)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHBDL1 rhomboid, veinlet-like 1 (Drosophila)
RIMS3 regulating synaptic membrane exocytosis 3
RSU1 Ras suppressor protein 1
RXRB retinoid X receptor, beta
SAPCD1 suppressor APC domain containing 1
SH3GL3 SH3-domain GRB2-like 3
SLC17A4 solute carrier family 17, member 4
SLC35E2 solute carrier family 35, member E2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SOX12 SRY (sex determining region Y)-box 12
SOX21 SRY (sex determining region Y)-box 21
SPHK2 sphingosine kinase 2
TCF25 transcription factor 25 (basic helix-loop-helix)
TMEM63A transmembrane protein 63A
TRAIP TRAF interacting protein
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TSC2 tuberous sclerosis 2
TSNAXIP1 translin-associated factor X interacting protein 1
WDTC1 WD and tetratricopeptide repeats 1
WNT10B wingless-type MMTV integration site family, member 10B
ZNF235 zinc finger protein 235
ZNF254 zinc finger protein 254
ZNF286A zinc finger protein 286A
ZNF500 zinc finger protein 500
ZNF614 zinc finger protein 614

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADGRL2 adhesion G protein-coupled receptor L2
ADM adrenomedullin
AGMAT agmatine ureohydrolase (agmatinase)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARRB2 arrestin, beta 2
ASB9 ankyrin repeat and SOCS box containing 9
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C3 complement component 3
C7ORF43 chromosome 7 open reading frame 43
CCDC121 coiled-coil domain containing 121
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CHST10 carbohydrate sulfotransferase 10
CIC capicua transcriptional repressor
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CST6 cystatin E/M
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
EFHD2 EF-hand domain family, member D2
ELOVL4 ELOVL fatty acid elongase 4
FBRS fibrosin
FBXO31 F-box protein 31
FILIP1L filamin A interacting protein 1-like
FLCN folliculin
FLJ22184
GAMT guanidinoacetate N-methyltransferase
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HSPA1L heat shock 70kDa protein 1-like
IFT22 intraflagellar transport 22
IL12RB1 interleukin 12 receptor, beta 1
INF2 inverted formin, FH2 and WH2 domain containing
IRF7 interferon regulatory factor 7
KCTD7 potassium channel tetramerization domain containing 7
KRT13 keratin 13, type I
LARP6 La ribonucleoprotein domain family, member 6
LIN7A lin-7 homolog A (C. elegans)
LYPD1 LY6/PLAUR domain containing 1
MED15 mediator complex subunit 15
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NABP2 nucleic acid binding protein 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPTX1 neuronal pentraxin I
NT5DC3 5'-nucleotidase domain containing 3
NXPH4 neurexophilin 4
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PCDHB13 protocadherin beta 13
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS16 protease, serine, 16 (thymus)
RIN2 Ras and Rab interactor 2
RLF rearranged L-myc fusion
RNF122 ring finger protein 122
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A2 S100 calcium binding protein A2
SAYSD1 SAYSVFN motif domain containing 1
SETD1A SET domain containing 1A
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRD5A3 steroid 5 alpha-reductase 3
STARD13 StAR-related lipid transfer (START) domain containing 13
STRA6 stimulated by retinoic acid 6
STRN4 striatin, calmodulin binding protein 4
STX1A syntaxin 1A (brain)
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D19 TBC1 domain family, member 19
TCTA T-cell leukemia translocation altered
TEP1 telomerase-associated protein 1
THBS3 thrombospondin 3
TLN1 talin 1
TMC7 transmembrane channel-like 7
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VAX2 ventral anterior homeobox 2
WASF1 WAS protein family, member 1
XK X-linked Kx blood group
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZFAND3 zinc finger, AN1-type domain 3
ZNF226 zinc finger protein 226
ZNF276 zinc finger protein 276
ZNF34 zinc finger protein 34
ZNF701 zinc finger protein 701
ZNF85 zinc finger protein 85
ZSCAN2 zinc finger and SCAN domain containing 2