cisapride-5305 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the cisapride-5305 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK2 aarF domain containing kinase 2
ADGRL1 adhesion G protein-coupled receptor L1
AK1 adenylate kinase 1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ARTN artemin
ASPH aspartate beta-hydroxylase
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
ATXN1 ataxin 1
BTBD7 BTB (POZ) domain containing 7
BTF3P11 basic transcription factor 3 pseudogene 11
C21ORF2 chromosome 21 open reading frame 2
CCL27 chemokine (C-C motif) ligand 27
CD22 CD22 molecule
CD82 CD82 molecule
CFAP70 cilia and flagella associated protein 70
CIC capicua transcriptional repressor
CLCA1 chloride channel accessory 1
COL1A1 collagen, type I, alpha 1
CORT cortistatin
CRABP1 cellular retinoic acid binding protein 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYHR1 cysteine/histidine-rich 1
DCAF15 DDB1 and CUL4 associated factor 15
DDIT3 DNA-damage-inducible transcript 3
DTNA dystrobrevin, alpha
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EML3 echinoderm microtubule associated protein like 3
EXOC7 exocyst complex component 7
FECH ferrochelatase
FHL1 four and a half LIM domains 1
FKBP8 FK506 binding protein 8, 38kDa
FLII flightless I homolog (Drosophila)
GPATCH3 G patch domain containing 3
HLA-B major histocompatibility complex, class I, B
HPS4 Hermansky-Pudlak syndrome 4
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IL1R1 interleukin 1 receptor, type I
ITSN1 intersectin 1 (SH3 domain protein)
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIF21B kinesin family member 21B
KLHL24 kelch-like family member 24
KRT17 keratin 17, type I
LIME1 Lck interacting transmembrane adaptor 1
LIN7B lin-7 homolog B (C. elegans)
LRP5L low density lipoprotein receptor-related protein 5-like
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP4 microtubule-associated protein 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED16 mediator complex subunit 16
METTL7A methyltransferase like 7A
MNX1 motor neuron and pancreas homeobox 1
NDE1 nudE neurodevelopment protein 1
NPIPB15 nuclear pore complex interacting protein family, member B15
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSBPL2 oxysterol binding protein-like 2
PDE4DIP phosphodiesterase 4D interacting protein
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKP3 plakophilin 3
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG1 phospholipase C, gamma 1
POLL polymerase (DNA directed), lambda
PRB3 proline-rich protein BstNI subfamily 3
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRR5 proline rich 5 (renal)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTRF polymerase I and transcript release factor
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB26 RAB26, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RASAL1 RAS protein activator like 1 (GAP1 like)
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RPGR retinitis pigmentosa GTPase regulator
RPH3AL rabphilin 3A-like (without C2 domains)
RPL10 ribosomal protein L10
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A11 S100 calcium binding protein A11
S100A4 S100 calcium binding protein A4
SGPL1 sphingosine-1-phosphate lyase 1
SGSM3 small G protein signaling modulator 3
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SMAD4 SMAD family member 4
SMG5 SMG5 nonsense mediated mRNA decay factor
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNGR3 synaptogyrin 3
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCP11L1 t-complex 11, testis-specific-like 1
TMEM121 transmembrane protein 121
TMEM183A transmembrane protein 183A
TMOD1 tropomodulin 1
TRADD TNFRSF1A-associated via death domain
TRIM21 tripartite motif containing 21
ZDHHC18 zinc finger, DHHC-type containing 18
ZER1 zyg-11 related, cell cycle regulator

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADGRA3 adhesion G protein-coupled receptor A3
AEN apoptosis enhancing nuclease
AKAP12 A kinase (PRKA) anchor protein 12
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATAD3A ATPase family, AAA domain containing 3A
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CENPC centromere protein C
CEP97 centrosomal protein 97kDa
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
ERCC6L excision repair cross-complementation group 6-like
FAM169A family with sequence similarity 169, member A
FAM175B family with sequence similarity 175, member B
FAM188A family with sequence similarity 188, member A
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAR1 GAR1 ribonucleoprotein
GDAP1 ganglioside induced differentiation associated protein 1
GNPDA1 glucosamine-6-phosphate deaminase 1
GPR19 G protein-coupled receptor 19
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
H2AFJ H2A histone family, member J
HIRIP3 HIRA interacting protein 3
HSF2 heat shock transcription factor 2
ILKAP integrin-linked kinase-associated serine/threonine phosphatase
IRF6 interferon regulatory factor 6
JADE1 jade family PHD finger 1
KDM5C lysine (K)-specific demethylase 5C
KIAA0513 KIAA0513
LACTB2 lactamase, beta 2
LINC00115 long intergenic non-protein coding RNA 115
LINS lines homolog (Drosophila)
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC49 leucine rich repeat containing 49
MAGEH1 melanoma antigen family H1
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL2B methyltransferase like 2B
MORC3 MORC family CW-type zinc finger 3
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NPY1R neuropeptide Y receptor Y1
PGP phosphoglycolate phosphatase
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLAC8 placenta-specific 8
PMP22 peripheral myelin protein 22
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPT2 palmitoyl-protein thioesterase 2
PROS1 protein S (alpha)
PTBP2 polypyrimidine tract binding protein 2
QTRT1 queuine tRNA-ribosyltransferase 1
RAB23 RAB23, member RAS oncogene family
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RNF38 ring finger protein 38
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPUSD2 RNA pseudouridylate synthase domain containing 2
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC35F5 solute carrier family 35, member F5
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMA4 glucuronidase, beta pseudogene
SOAT1 sterol O-acyltransferase 1
SPHK1 sphingosine kinase 1
STK16 serine/threonine kinase 16
SYNJ2BP synaptojanin 2 binding protein
TAGLN transgelin
THAP1 THAP domain containing, apoptosis associated protein 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMC7 transmembrane channel-like 7
UBQLN4 ubiquilin 4
WDR7 WD repeat domain 7
ZBTB39 zinc finger and BTB domain containing 39
ZFP30 ZFP30 zinc finger protein
ZNF205 zinc finger protein 205
ZNF23 zinc finger protein 23
ZNF250 zinc finger protein 250
ZNF273 zinc finger protein 273
ZNF468 zinc finger protein 468
ZNF571 zinc finger protein 571
ZNF586 zinc finger protein 586
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675