cisapride-6706 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the cisapride-6706 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADGRA2 adhesion G protein-coupled receptor A2
ADGRF5 adhesion G protein-coupled receptor F5
AHSG alpha-2-HS-glycoprotein
ARMC6 armadillo repeat containing 6
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C1S complement component 1, s subcomponent
C3 complement component 3
C9ORF156 chromosome 9 open reading frame 156
CA1 carbonic anhydrase I
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CD58 CD58 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CISH cytokine inducible SH2-containing protein
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CNGB3 cyclic nucleotide gated channel beta 3
CPN2 carboxypeptidase N, polypeptide 2
CSF1 colony stimulating factor 1 (macrophage)
CTNS cystinosin, lysosomal cystine transporter
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DSCAM Down syndrome cell adhesion molecule
EBF2 early B-cell factor 2
EFR3B EFR3 homolog B (S. cerevisiae)
FAM63A family with sequence similarity 63, member A
FGF20 fibroblast growth factor 20
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GATA4 GATA binding protein 4
GJD2 gap junction protein, delta 2, 36kDa
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPR22 G protein-coupled receptor 22
HABP4 hyaluronan binding protein 4
HLF hepatic leukemia factor
HOXD9 homeobox D9
INADL InaD-like (Drosophila)
ING4 inhibitor of growth family, member 4
JADE2 jade family PHD finger 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KDM4C lysine (K)-specific demethylase 4C
KDM6B lysine (K)-specific demethylase 6B
KRT37 keratin 37, type I
LEFTY1 left-right determination factor 1
LIMD1 LIM domains containing 1
LOC647070 uncharacterized LOC647070
LOX lysyl oxidase
LRRC2 leucine rich repeat containing 2
LY9 lymphocyte antigen 9
MAGEA10 melanoma antigen family A10
MAGEA5 melanoma antigen family A5
MAPK10 mitogen-activated protein kinase 10
MBD2 methyl-CpG binding domain protein 2
MED25 mediator complex subunit 25
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MORC1 MORC family CW-type zinc finger 1
MR1 major histocompatibility complex, class I-related
MTCP1 mature T-cell proliferation 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NR1H4 nuclear receptor subfamily 1, group H, member 4
OLFM4 olfactomedin 4
PCDH11Y protocadherin 11 Y-linked
PCDHB13 protocadherin beta 13
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PKLR pyruvate kinase, liver and RBC
PKNOX2 PBX/knotted 1 homeobox 2
PLCL2 phospholipase C-like 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRAMEF11 PRAME family member 11
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RFPL1S RFPL1 antisense RNA 1
RGS5 regulator of G-protein signaling 5
RPH3AL rabphilin 3A-like (without C2 domains)
RUNX1 runt-related transcription factor 1
SAYSD1 SAYSVFN motif domain containing 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SIRT5 sirtuin 5
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SNED1 sushi, nidogen and EGF-like domains 1
STC1 stanniocalcin 1
TBC1D2 TBC1 domain family, member 2
TBX1 T-box 1
TEX13B testis expressed 13B
TLDC1 TBC/LysM-associated domain containing 1
TLX3 T-cell leukemia homeobox 3
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TTC22 tetratricopeptide repeat domain 22
TUBA4B tubulin, alpha 4b
UBE2I ubiquitin-conjugating enzyme E2I
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZMAT4 zinc finger, matrin-type 4
ZNF280A zinc finger protein 280A
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ALG12 ALG12, alpha-1,6-mannosyltransferase
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BEX1 brain expressed, X-linked 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C17ORF70 chromosome 17 open reading frame 70
C1RL complement component 1, r subcomponent-like
C5ORF45 chromosome 5 open reading frame 45
CAPN5 calpain 5
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCP110 centriolar coiled coil protein 110kDa
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEP85 centrosomal protein 85kDa
CHM choroideremia (Rab escort protein 1)
CHRDL1 chordin-like 1
CLDND1 claudin domain containing 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CORO1A coronin, actin binding protein, 1A
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DCLRE1A DNA cross-link repair 1A
DDN dendrin
DEAF1 DEAF1 transcription factor
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EXOC5 exocyst complex component 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP5 FK506 binding protein 5
GFOD2 glucose-fructose oxidoreductase domain containing 2
GJC1 gap junction protein, gamma 1, 45kDa
GMPR guanosine monophosphate reductase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPNMB glycoprotein (transmembrane) nmb
GRAMD1C GRAM domain containing 1C
GTF2I general transcription factor IIi
HAMP hepcidin antimicrobial peptide
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BN histone cluster 1, H2bn
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOOK1 hook microtubule-tethering protein 1
HOXA7 homeobox A7
HP1BP3 heterochromatin protein 1, binding protein 3
IREB2 iron-responsive element binding protein 2
IRF1 interferon regulatory factor 1
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KIAA1456 KIAA1456
KIF13B kinesin family member 13B
KRT6A keratin 6A, type II
KRT9 keratin 9, type I
LIME1 Lck interacting transmembrane adaptor 1
LINC00472 long intergenic non-protein coding RNA 472
LRP3 low density lipoprotein receptor-related protein 3
LRRC61 leucine rich repeat containing 61
LYPD3 LY6/PLAUR domain containing 3
MB myoglobin
METTL16 methyltransferase like 16
MOCS3 molybdenum cofactor synthesis 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPS18C mitochondrial ribosomal protein S18C
MYL5 myosin, light chain 5, regulatory
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NABP2 nucleic acid binding protein 2
NDRG4 NDRG family member 4
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
PARM1 prostate androgen-regulated mucin-like protein 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLAG1 pleiomorphic adenoma gene 1
POLM polymerase (DNA directed), mu
PRICKLE3 prickle homolog 3 (Drosophila)
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB17 RAB17, member RAS oncogene family
RNF126P1 ring finger protein 126 pseudogene 1
ROR1 receptor tyrosine kinase-like orphan receptor 1
S100A3 S100 calcium binding protein A3
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERGEF secretion regulating guanine nucleotide exchange factor
SH2D2A SH2 domain containing 2A
SNAI2 snail family zinc finger 2
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPTBN2 spectrin, beta, non-erythrocytic 2
STK16 serine/threonine kinase 16
STRN striatin, calmodulin binding protein
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
THRAP3 thyroid hormone receptor associated protein 3
TM7SF2 transmembrane 7 superfamily member 2
TOM1 target of myb1 (chicken)
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIM25 tripartite motif containing 25
TTLL1 tubulin tyrosine ligase-like family member 1
WDR62 WD repeat domain 62
XAB2 XPA binding protein 2