| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the citalopram-4377 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADCY1 | adenylate cyclase 1 (brain) |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| ADORA1 | adenosine A1 receptor |
| AHSP | alpha hemoglobin stabilizing protein |
| AMELY | amelogenin, Y-linked |
| ANK1 | ankyrin 1, erythrocytic |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| APOC1 | apolipoprotein C-I |
| ARHGAP26 | Rho GTPase activating protein 26 |
| AUTS2 | autism susceptibility candidate 2 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BEST2 | bestrophin 2 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CCT8L2 | chaperonin containing TCP1, subunit 8 (theta)-like 2 |
| CD58 | CD58 molecule |
| CFAP45 | cilia and flagella associated protein 45 |
| CHRD | chordin |
| CLEC4A | C-type lectin domain family 4, member A |
| CLTA | clathrin, light chain A |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CNN1 | calponin 1, basic, smooth muscle |
| CTIF | CBP80/20-dependent translation initiation factor |
| DAPK2 | death-associated protein kinase 2 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FZD5 | frizzled class receptor 5 |
| GABARAPL3 | GABA(A) receptors associated protein like 3, pseudogene |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GIMAP6 | GTPase, IMAP family member 6 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPR15 | G protein-coupled receptor 15 |
| GRM2 | glutamate receptor, metabotropic 2 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HFE | hemochromatosis |
| HOXC10 | homeobox C10 |
| HRH2 | histamine receptor H2 |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
| IFT54 | intraflagellar transport 54 |
| IL23A | interleukin 23, alpha subunit p19 |
| IL36G | interleukin 36, gamma |
| IRF8 | interferon regulatory factor 8 |
| ITGA9 | integrin, alpha 9 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KCNH6 | potassium channel, voltage gated eag related subfamily H, member 6 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| LAMA4 | laminin, alpha 4 |
| LAMC3 | laminin, gamma 3 |
| LATS1 | large tumor suppressor kinase 1 |
| LOC79999 | uncharacterized LOC79999 |
| MAB21L1 | mab-21-like 1 (C. elegans) |
| MBD2 | methyl-CpG binding domain protein 2 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MED25 | mediator complex subunit 25 |
| MST1 | macrophage stimulating 1 |
| MXD4 | MAX dimerization protein 4 |
| NNMT | nicotinamide N-methyltransferase |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PCDHB11 | protocadherin beta 11 |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| PLCH1 | phospholipase C, eta 1 |
| PNMA3 | paraneoplastic Ma antigen 3 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PROL1 | proline rich, lacrimal 1 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| STAB1 | stabilin 1 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TAS2R4 | taste receptor, type 2, member 4 |
| TBC1D22B | TBC1 domain family, member 22B |
| TFR2 | transferrin receptor 2 |
| TGM2 | transglutaminase 2 |
| TMEM144 | transmembrane protein 144 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| WTAP | Wilms tumor 1 associated protein |
| XAF1 | XIAP associated factor 1 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF155 | zinc finger protein 155 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP10D | ATPase, class V, type 10D |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CALB2 | calbindin 2 |
| CASC1 | cancer susceptibility candidate 1 |
| CCDC69 | coiled-coil domain containing 69 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CNTFR | ciliary neurotrophic factor receptor |
| CRLF1 | cytokine receptor-like factor 1 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DNASE1L2 | deoxyribonuclease I-like 2 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOC2A | double C2-like domains, alpha |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FBXO2 | F-box protein 2 |
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta |
| GFI1 | growth factor independent 1 transcription repressor |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HDAC7 | histone deacetylase 7 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H3B | histone cluster 1, H3b |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXA4 | homeobox A4 |
| HOXD11 | homeobox D11 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| ISL1 | ISL LIM homeobox 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL21 | kelch-like family member 21 |
| KLHL25 | kelch-like family member 25 |
| KRT9 | keratin 9, type I |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP2 | microtubule-associated protein 2 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MEFV | Mediterranean fever |
| MFAP2 | microfibrillar-associated protein 2 |
| NME5 | NME/NM23 family member 5 |
| NRTN | neurturin |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCDH17 | protocadherin 17 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PRSS53 | protease, serine, 53 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB36 | RAB36, member RAS oncogene family |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUNDC3B | RUN domain containing 3B |
| S100A7 | S100 calcium binding protein A7 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SGCE | sarcoglycan, epsilon |
| SKI | SKI proto-oncogene |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SNTA1 | syntrophin, alpha 1 |
| SOAT2 | sterol O-acyltransferase 2 |
| STEAP4 | STEAP family member 4 |
| TEX14 | testis expressed 14 |
| TEX40 | testis expressed 40 |
| THBS3 | thrombospondin 3 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIM21 | tripartite motif containing 21 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TSGA10 | testis specific, 10 |
| TUBA3C | tubulin, alpha 3c |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF250 | zinc finger protein 250 |
| ZNF286A | zinc finger protein 286A |