citalopram-4377 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the citalopram-4377 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADCY1 adenylate cyclase 1 (brain)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADORA1 adenosine A1 receptor
AHSP alpha hemoglobin stabilizing protein
AMELY amelogenin, Y-linked
ANK1 ankyrin 1, erythrocytic
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOC1 apolipoprotein C-I
ARHGAP26 Rho GTPase activating protein 26
AUTS2 autism susceptibility candidate 2
BCL2 B-cell CLL/lymphoma 2
BEST2 bestrophin 2
CA5B carbonic anhydrase VB, mitochondrial
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2
CD58 CD58 molecule
CFAP45 cilia and flagella associated protein 45
CHRD chordin
CLEC4A C-type lectin domain family 4, member A
CLTA clathrin, light chain A
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNN1 calponin 1, basic, smooth muscle
CTIF CBP80/20-dependent translation initiation factor
DAPK2 death-associated protein kinase 2
DEFA6 defensin, alpha 6, Paneth cell-specific
DGCR8 DGCR8 microprocessor complex subunit
DGKG diacylglycerol kinase, gamma 90kDa
DNAH7 dynein, axonemal, heavy chain 7
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELF5 E74-like factor 5 (ets domain transcription factor)
ELOVL5 ELOVL fatty acid elongase 5
F13A1 coagulation factor XIII, A1 polypeptide
FZD5 frizzled class receptor 5
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GIF gastric intrinsic factor (vitamin B synthesis)
GIMAP6 GTPase, IMAP family member 6
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR15 G protein-coupled receptor 15
GRM2 glutamate receptor, metabotropic 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HFE hemochromatosis
HOXC10 homeobox C10
HRH2 histamine receptor H2
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IFT54 intraflagellar transport 54
IL23A interleukin 23, alpha subunit p19
IL36G interleukin 36, gamma
IRF8 interferon regulatory factor 8
ITGA9 integrin, alpha 9
ITPK1 inositol-tetrakisphosphate 1-kinase
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
LAMA4 laminin, alpha 4
LAMC3 laminin, gamma 3
LATS1 large tumor suppressor kinase 1
LOC79999 uncharacterized LOC79999
MAB21L1 mab-21-like 1 (C. elegans)
MBD2 methyl-CpG binding domain protein 2
MBNL2 muscleblind-like splicing regulator 2
MED25 mediator complex subunit 25
MST1 macrophage stimulating 1
MXD4 MAX dimerization protein 4
NNMT nicotinamide N-methyltransferase
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
PCDHB11 protocadherin beta 11
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PLCH1 phospholipase C, eta 1
PNMA3 paraneoplastic Ma antigen 3
PRB4 proline-rich protein BstNI subfamily 4
PROL1 proline rich, lacrimal 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
SCAND2P SCAN domain containing 2 pseudogene
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
STAB1 stabilin 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAS2R4 taste receptor, type 2, member 4
TBC1D22B TBC1 domain family, member 22B
TFR2 transferrin receptor 2
TGM2 transglutaminase 2
TMEM144 transmembrane protein 144
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TREM1 triggering receptor expressed on myeloid cells 1
WTAP Wilms tumor 1 associated protein
XAF1 XIAP associated factor 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
XYLB xylulokinase homolog (H. influenzae)
ZC3H13 zinc finger CCCH-type containing 13
ZFPL1 zinc finger protein-like 1
ZNF155 zinc finger protein 155

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AGMAT agmatine ureohydrolase (agmatinase)
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP10D ATPase, class V, type 10D
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
C2ORF27A chromosome 2 open reading frame 27A
C8ORF60 chromosome 8 open reading frame 60
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALB2 calbindin 2
CASC1 cancer susceptibility candidate 1
CCDC69 coiled-coil domain containing 69
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNTFR ciliary neurotrophic factor receptor
CRLF1 cytokine receptor-like factor 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNASE1L2 deoxyribonuclease I-like 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOC2A double C2-like domains, alpha
ELSPBP1 epididymal sperm binding protein 1
EXD3 exonuclease 3'-5' domain containing 3
FBXO2 F-box protein 2
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GFI1 growth factor independent 1 transcription repressor
GPRC5D G protein-coupled receptor, class C, group 5, member D
GSTCD glutathione S-transferase, C-terminal domain containing
HDAC7 histone deacetylase 7
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H1D histone cluster 1, H1d
HIST1H3B histone cluster 1, H3b
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA4 homeobox A4
HOXD11 homeobox D11
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ISL1 ISL LIM homeobox 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KDM8 lysine (K)-specific demethylase 8
KLHL21 kelch-like family member 21
KLHL25 kelch-like family member 25
KRT9 keratin 9, type I
LARP6 La ribonucleoprotein domain family, member 6
LOC100286895 cell division cycle 27 homolog pseudogene
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP2 microtubule-associated protein 2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MEFV Mediterranean fever
MFAP2 microfibrillar-associated protein 2
NME5 NME/NM23 family member 5
NRTN neurturin
NT5E 5'-nucleotidase, ecto (CD73)
NXPE3 neurexophilin and PC-esterase domain family, member 3
PADI1 peptidyl arginine deiminase, type I
PCDH17 protocadherin 17
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHS1 pleckstrin homology domain containing, family S member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRSS53 protease, serine, 53
PTPRS protein tyrosine phosphatase, receptor type, S
RAB36 RAB36, member RAS oncogene family
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RFPL1S RFPL1 antisense RNA 1
RHOBTB2 Rho-related BTB domain containing 2
RNF126P1 ring finger protein 126 pseudogene 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNDC3B RUN domain containing 3B
S100A7 S100 calcium binding protein A7
SAYSD1 SAYSVFN motif domain containing 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SGCE sarcoglycan, epsilon
SKI SKI proto-oncogene
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SNTA1 syntrophin, alpha 1
SOAT2 sterol O-acyltransferase 2
STEAP4 STEAP family member 4
TEX14 testis expressed 14
TEX40 testis expressed 40
THBS3 thrombospondin 3
TM4SF4 transmembrane 4 L six family member 4
TM6SF1 transmembrane 6 superfamily member 1
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM21 tripartite motif containing 21
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSGA10 testis specific, 10
TUBA3C tubulin, alpha 3c
ZBED1 zinc finger, BED-type containing 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF250 zinc finger protein 250
ZNF286A zinc finger protein 286A