| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the citiolone-2176 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AGTR1 | angiotensin II receptor, type 1 |
| ANKRD40 | ankyrin repeat domain 40 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BEST1 | bestrophin 1 |
| BIN1 | bridging integrator 1 |
| BMP7 | bone morphogenetic protein 7 |
| C16ORF70 | chromosome 16 open reading frame 70 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCDC33 | coiled-coil domain containing 33 |
| CD24 | CD24 molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CLTB | clathrin, light chain B |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CSNK1E | casein kinase 1, epsilon |
| CTIF | CBP80/20-dependent translation initiation factor |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOPEY2 | dopey family member 2 |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPHB2 | EPH receptor B2 |
| EXOSC2 | exosome component 2 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FCAR | Fc fragment of IgA receptor |
| FGB | fibrinogen beta chain |
| FGF23 | fibroblast growth factor 23 |
| FKBP5 | FK506 binding protein 5 |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GLP1R | glucagon-like peptide 1 receptor |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HNF1B | HNF1 homeobox B |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IL1R2 | interleukin 1 receptor, type II |
| IL6ST | interleukin 6 signal transducer |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JAK3 | Janus kinase 3 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LAMC3 | laminin, gamma 3 |
| LMO7 | LIM domain 7 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAP4 | microtubule-associated protein 4 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MIR22HG | MIR22 host gene |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NKX2-5 | NK2 homeobox 5 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PERP | PERP, TP53 apoptosis effector |
| RAB40B | RAB40B, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RASAL2 | RAS protein activator like 2 |
| RB1 | retinoblastoma 1 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RDH16 | retinol dehydrogenase 16 (all-trans) |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SLAMF7 | SLAM family member 7 |
| SLAMF8 | SLAM family member 8 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLN | sarcolipin |
| SPAG8 | sperm associated antigen 8 |
| SPRR2B | small proline-rich protein 2B |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STOM | stomatin |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYCE1L | synaptonemal complex central element protein 1-like |
| SYN2 | synapsin II |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TAOK2 | TAO kinase 2 |
| THBS1 | thrombospondin 1 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TRAPPC9 | trafficking protein particle complex 9 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TTC30A | tetratricopeptide repeat domain 30A |
| VASH1 | vasohibin 1 |
| YOD1 | YOD1 deubiquitinase |
| ZBTB16 | zinc finger and BTB domain containing 16 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| ARMC7 | armadillo repeat containing 7 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| CCDC106 | coiled-coil domain containing 106 |
| CCDC71 | coiled-coil domain containing 71 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEP170B | centrosomal protein 170B |
| CPTP | ceramide-1-phosphate transfer protein |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DBR1 | debranching RNA lariats 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EPHA4 | EPH receptor A4 |
| ERCC6L | excision repair cross-complementation group 6-like |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOSC1 | exosome component 1 |
| FAM127B | family with sequence similarity 127, member B |
| FGL1 | fibrinogen-like 1 |
| FHL3 | four and a half LIM domains 3 |
| FOXN2 | forkhead box N2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2AI | histone cluster 1, H2ai |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0754 | KIAA0754 |
| KLHL28 | kelch-like family member 28 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAK | male germ cell-associated kinase |
| MAPK12 | mitogen-activated protein kinase 12 |
| MBD5 | methyl-CpG binding domain protein 5 |
| MDM4 | MDM4, p53 regulator |
| MKL2 | MKL/myocardin-like 2 |
| MKRN3 | makorin ring finger protein 3 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NBEA | neurobeachin |
| NDE1 | nudE neurodevelopment protein 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NKX3-2 | NK3 homeobox 2 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLCD1 | phospholipase C, delta 1 |
| PLP1 | proteolipid protein 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PNOC | prepronociceptin |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| RAB23 | RAB23, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RECQL4 | RecQ protein-like 4 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SPAG1 | sperm associated antigen 1 |
| SPI1 | Spi-1 proto-oncogene |
| STRN | striatin, calmodulin binding protein |
| SUSD6 | sushi domain containing 6 |
| SYCP2 | synaptonemal complex protein 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCTN2 | tectonic family member 2 |
| TESK1 | testis-specific kinase 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMEM183A | transmembrane protein 183A |
| TMEM242 | transmembrane protein 242 |
| TPM3 | tropomyosin 3 |
| TSPAN5 | tetraspanin 5 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBB2A | tubulin, beta 2A class IIa |
| USB1 | U6 snRNA biogenesis 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF134 | zinc finger protein 134 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF493 | zinc finger protein 493 |
| ZNF747 | zinc finger protein 747 |