citiolone-3755 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the citiolone-3755 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADRB1 adrenoceptor beta 1
ANGPTL2 angiopoietin-like 2
ATP10A ATPase, class V, type 10A
BAGE B melanoma antigen
BMP1 bone morphogenetic protein 1
C14ORF79 chromosome 14 open reading frame 79
CALCB calcitonin-related polypeptide beta
CCDC28B coiled-coil domain containing 28B
CD33 CD33 molecule
CDC25C cell division cycle 25C
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLEC4E C-type lectin domain family 4, member E
CRYGC crystallin, gamma C
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DEPDC5 DEP domain containing 5
DMP1 dentin matrix acidic phosphoprotein 1
DUSP13 dual specificity phosphatase 13
EVI2A ecotropic viral integration site 2A
FBRS fibrosin
FNDC4 fibronectin type III domain containing 4
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GGT1 gamma-glutamyltransferase 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR85 G protein-coupled receptor 85
GRIP2 glutamate receptor interacting protein 2
HIST1H3J histone cluster 1, H3j
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HUNK hormonally up-regulated Neu-associated kinase
IFNA16 interferon, alpha 16
IFT140 intraflagellar transport 140
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIF1A kinesin family member 1A
KLK2 kallikrein-related peptidase 2
LARP4B La ribonucleoprotein domain family, member 4B
LINC00216 long intergenic non-protein coding RNA 216
LMO1 LIM domain only 1 (rhombotin 1)
LMO3 LIM domain only 3 (rhombotin-like 2)
LRRN2 leucine rich repeat neuronal 2
LSP1 lymphocyte-specific protein 1
MAPK10 mitogen-activated protein kinase 10
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MOBP myelin-associated oligodendrocyte basic protein
MOGAT2 monoacylglycerol O-acyltransferase 2
MSI1 musashi RNA-binding protein 1
MUC3B mucin 3B, cell surface associated
NDNF neuron-derived neurotrophic factor
NPY2R neuropeptide Y receptor Y2
NR5A2 nuclear receptor subfamily 5, group A, member 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PARP8 poly (ADP-ribose) polymerase family, member 8
PCDHB13 protocadherin beta 13
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLD1 phospholipase D1, phosphatidylcholine-specific
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRAMEF10 PRAME family member 10
PRDM16 PR domain containing 16
PRKD1 protein kinase D1
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB5C RAB5C, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RASIP1 Ras interacting protein 1
RASL11B RAS-like, family 11, member B
REEP2 receptor accessory protein 2
RPL7 ribosomal protein L7
RUNX1 runt-related transcription factor 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SEZ6L seizure related 6 homolog (mouse)-like
SIRPA signal-regulatory protein alpha
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SOX2 SRY (sex determining region Y)-box 2
STAT2 signal transducer and activator of transcription 2, 113kDa
STX11 syntaxin 11
SYNGR3 synaptogyrin 3
T T, brachyury homolog (mouse)
TCP10 t-complex 10
TLR1 toll-like receptor 1
TMEM176A transmembrane protein 176A
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VCX2 variable charge, X-linked 2
YBX2 Y box binding protein 2
ZC3H7B zinc finger CCCH-type containing 7B
ZER1 zyg-11 related, cell cycle regulator
ZNF3 zinc finger protein 3
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAM15 ADAM metallopeptidase domain 15
AKAP5 A kinase (PRKA) anchor protein 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARC activity-regulated cytoskeleton-associated protein
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTC betacellulin
CAMKMT calmodulin-lysine N-methyltransferase
CCDC106 coiled-coil domain containing 106
CCDC186 coiled-coil domain containing 186
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK6 cyclin-dependent kinase 6
CFAP69 cilia and flagella associated protein 69
CGREF1 cell growth regulator with EF-hand domain 1
CHM choroideremia (Rab escort protein 1)
CHRDL1 chordin-like 1
CRMP1 collapsin response mediator protein 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF13 DDB1 and CUL4 associated factor 13
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DENND5B DENN/MADD domain containing 5B
DTX2 deltex 2, E3 ubiquitin ligase
FGF23 fibroblast growth factor 23
FKBP10 FK506 binding protein 10, 65 kDa
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GDAP1 ganglioside induced differentiation associated protein 1
GPRASP1 G protein-coupled receptor associated sorting protein 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HMGB3P1 high mobility group box 3 pseudogene 1
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
IPO8 importin 8
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KLHL28 kelch-like family member 28
LINC00472 long intergenic non-protein coding RNA 472
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LY86 lymphocyte antigen 86
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MRPS18C mitochondrial ribosomal protein S18C
MXD3 MAX dimerization protein 3
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NLGN1 neuroligin 1
NPM3 nucleophosmin/nucleoplasmin 3
OSMR oncostatin M receptor
OVGP1 oviductal glycoprotein 1, 120kDa
PADI1 peptidyl arginine deiminase, type I
PDZK1 PDZ domain containing 1
PHF14 PHD finger protein 14
PICK1 protein interacting with PRKCA 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRR14L proline rich 14-like
PRR15L proline rich 15-like
PTPRS protein tyrosine phosphatase, receptor type, S
PWAR5 Prader Willi/Angelman region RNA 5
QPCTL glutaminyl-peptide cyclotransferase-like
RAB4B RAB4B, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPS17P5 ribosomal protein S17 pseudogene 5
RUNDC3B RUN domain containing 3B
RUNX1-IT1 RUNX1 intronic transcript 1
S1PR1 sphingosine-1-phosphate receptor 1
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SETD1A SET domain containing 1A
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC25A40 solute carrier family 25, member 40
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPRYD7 SPRY domain containing 7
STK16 serine/threonine kinase 16
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TM6SF1 transmembrane 6 superfamily member 1
TMEM209 transmembrane protein 209
TRAIP TRAF interacting protein
TRDMT1 tRNA aspartic acid methyltransferase 1
TSKU tsukushi, small leucine rich proteoglycan
TTC30A tetratricopeptide repeat domain 30A
UTRN utrophin
VLDLR very low density lipoprotein receptor
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF205 zinc finger protein 205
ZNF227 zinc finger protein 227
ZNF639 zinc finger protein 639
ZNF669 zinc finger protein 669