| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the citiolone-3755 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS20 | ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide |
| ADRB1 | adrenoceptor beta 1 |
| ANGPTL2 | angiopoietin-like 2 |
| ATP10A | ATPase, class V, type 10A |
| BAGE | B melanoma antigen |
| BMP1 | bone morphogenetic protein 1 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CALCB | calcitonin-related polypeptide beta |
| CCDC28B | coiled-coil domain containing 28B |
| CD33 | CD33 molecule |
| CDC25C | cell division cycle 25C |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 |
| CLEC4E | C-type lectin domain family 4, member E |
| CRYGC | crystallin, gamma C |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DEPDC5 | DEP domain containing 5 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DUSP13 | dual specificity phosphatase 13 |
| EVI2A | ecotropic viral integration site 2A |
| FBRS | fibrosin |
| FNDC4 | fibronectin type III domain containing 4 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GGT1 | gamma-glutamyltransferase 1 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR85 | G protein-coupled receptor 85 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HIST1H3J | histone cluster 1, H3j |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| HUNK | hormonally up-regulated Neu-associated kinase |
| IFNA16 | interferon, alpha 16 |
| IFT140 | intraflagellar transport 140 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIF1A | kinesin family member 1A |
| KLK2 | kallikrein-related peptidase 2 |
| LARP4B | La ribonucleoprotein domain family, member 4B |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LMO1 | LIM domain only 1 (rhombotin 1) |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| LRRN2 | leucine rich repeat neuronal 2 |
| LSP1 | lymphocyte-specific protein 1 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MSI1 | musashi RNA-binding protein 1 |
| MUC3B | mucin 3B, cell surface associated |
| NDNF | neuron-derived neurotrophic factor |
| NPY2R | neuropeptide Y receptor Y2 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PCDHB13 | protocadherin beta 13 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PRAMEF10 | PRAME family member 10 |
| PRDM16 | PR domain containing 16 |
| PRKD1 | protein kinase D1 |
| PTPRG | protein tyrosine phosphatase, receptor type, G |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAB5C | RAB5C, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RASIP1 | Ras interacting protein 1 |
| RASL11B | RAS-like, family 11, member B |
| REEP2 | receptor accessory protein 2 |
| RPL7 | ribosomal protein L7 |
| RUNX1 | runt-related transcription factor 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SIRPA | signal-regulatory protein alpha |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STX11 | syntaxin 11 |
| SYNGR3 | synaptogyrin 3 |
| T | T, brachyury homolog (mouse) |
| TCP10 | t-complex 10 |
| TLR1 | toll-like receptor 1 |
| TMEM176A | transmembrane protein 176A |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VCX2 | variable charge, X-linked 2 |
| YBX2 | Y box binding protein 2 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF3 | zinc finger protein 3 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARC | activity-regulated cytoskeleton-associated protein |
| BAK1 | BCL2-antagonist/killer 1 |
| BAX | BCL2-associated X protein |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BTC | betacellulin |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC106 | coiled-coil domain containing 106 |
| CCDC186 | coiled-coil domain containing 186 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDK6 | cyclin-dependent kinase 6 |
| CFAP69 | cilia and flagella associated protein 69 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHM | choroideremia (Rab escort protein 1) |
| CHRDL1 | chordin-like 1 |
| CRMP1 | collapsin response mediator protein 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DENND5B | DENN/MADD domain containing 5B |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| FGF23 | fibroblast growth factor 23 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA2 | heat shock 70kDa protein 2 |
| IPO8 | importin 8 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KLHL28 | kelch-like family member 28 |
| LINC00472 | long intergenic non-protein coding RNA 472 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LY86 | lymphocyte antigen 86 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MXD3 | MAX dimerization protein 3 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NLGN1 | neuroligin 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OSMR | oncostatin M receptor |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PADI1 | peptidyl arginine deiminase, type I |
| PDZK1 | PDZ domain containing 1 |
| PHF14 | PHD finger protein 14 |
| PICK1 | protein interacting with PRKCA 1 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRR14L | proline rich 14-like |
| PRR15L | proline rich 15-like |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB4B | RAB4B, member RAS oncogene family |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| RUNDC3B | RUN domain containing 3B |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SETD1A | SET domain containing 1A |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SPRYD7 | SPRY domain containing 7 |
| STK16 | serine/threonine kinase 16 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM209 | transmembrane protein 209 |
| TRAIP | TRAF interacting protein |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTC30A | tetratricopeptide repeat domain 30A |
| UTRN | utrophin |
| VLDLR | very low density lipoprotein receptor |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZNF205 | zinc finger protein 205 |
| ZNF227 | zinc finger protein 227 |
| ZNF639 | zinc finger protein 639 |
| ZNF669 | zinc finger protein 669 |