| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the citiolone-3836 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| AFF2 | AF4/FMR2 family, member 2 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANGPTL2 | angiopoietin-like 2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARSD | arylsulfatase D |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CAPZB | capping protein (actin filament) muscle Z-line, beta |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CCNK | cyclin K |
| CD1E | CD1e molecule |
| CD34 | CD34 molecule |
| CD6 | CD6 molecule |
| CIITA | class II, major histocompatibility complex, transactivator |
| CLEC2B | C-type lectin domain family 2, member B |
| CNTNAP2 | contactin associated protein-like 2 |
| CPA4 | carboxypeptidase A4 |
| CROCCP3 | ciliary rootlet coiled-coil, rootletin pseudogene 3 |
| CUL7 | cullin 7 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DIO2 | deiodinase, iodothyronine, type II |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| DUSP1 | dual specificity phosphatase 1 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| EFNB3 | ephrin-B3 |
| ESR1 | estrogen receptor 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR176 | G protein-coupled receptor 176 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTA1 | glutathione S-transferase alpha 1 |
| HIST1H2AB | histone cluster 1, H2ab |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFT27 | intraflagellar transport 27 |
| IL12A | interleukin 12A |
| IL17RC | interleukin 17 receptor C |
| INHBC | inhibin, beta C |
| IRS4 | insulin receptor substrate 4 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLHL22 | kelch-like family member 22 |
| KRT9 | keratin 9, type I |
| LHX2 | LIM homeobox 2 |
| LMAN1 | lectin, mannose-binding, 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MNMIP1 | manchette microtubule inner protein 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NIPAL2 | NIPA-like domain containing 2 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NUP214 | nucleoporin 214kDa |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| OGFR | opioid growth factor receptor |
| PHF14 | PHD finger protein 14 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLAGL2 | pleiomorphic adenoma gene-like 2 |
| PLK3 | polo-like kinase 3 |
| PML | promyelocytic leukemia |
| POFUT1 | protein O-fucosyltransferase 1 |
| POM121 | POM121 transmembrane nucleoporin |
| POU5F1B | POU class 5 homeobox 1B |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PTMS | parathymosin |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RASA3 | RAS p21 protein activator 3 |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RXRB | retinoid X receptor, beta |
| SAMD4B | sterile alpha motif domain containing 4B |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SP1 | Sp1 transcription factor |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBC1D22B | TBC1 domain family, member 22B |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TP63 | tumor protein p63 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRBC1 | T cell receptor beta constant 1 |
| ZNF506 | zinc finger protein 506 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| AFAP1 | actin filament associated protein 1 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BST2 | bone marrow stromal cell antigen 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C4BPA | complement component 4 binding protein, alpha |
| C5AR2 | complement component 5a receptor 2 |
| CCDC25 | coiled-coil domain containing 25 |
| CD80 | CD80 molecule |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CIC | capicua transcriptional repressor |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| CUL9 | cullin 9 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DMTN | dematin actin binding protein |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP13 | dual specificity phosphatase 13 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EMID1 | EMI domain containing 1 |
| EPHB6 | EPH receptor B6 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FGL1 | fibrinogen-like 1 |
| FILIP1L | filamin A interacting protein 1-like |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GK3P | glycerol kinase 3 pseudogene |
| GPR21 | G protein-coupled receptor 21 |
| HDAC4 | histone deacetylase 4 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H4C | histone cluster 1, H4c |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFNA14 | interferon, alpha 14 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KRT15 | keratin 15, type I |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LMNB1 | lamin B1 |
| LOC730101 | uncharacterized LOC730101 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MID1IP1 | MID1 interacting protein 1 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MTA2 | metastasis associated 1 family, member 2 |
| NEK11 | NIMA-related kinase 11 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOTCH1 | notch 1 |
| NPTX1 | neuronal pentraxin I |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| OTUD3 | OTU deubiquitinase 3 |
| OVOL1 | ovo-like zinc finger 1 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PODXL2 | podocalyxin-like 2 |
| RPL10L | ribosomal protein L10-like |
| S100A9 | S100 calcium binding protein A9 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNX15 | sorting nexin 15 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STON1 | stonin 1 |
| TCTN2 | tectonic family member 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| WDR62 | WD repeat domain 62 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF286A | zinc finger protein 286A |
| ZNF35 | zinc finger protein 35 |
| ZNF41 | zinc finger protein 41 |
| ZNF639 | zinc finger protein 639 |
| ZNF747 | zinc finger protein 747 |