citiolone-3836 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the citiolone-3836 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADGRB1 adhesion G protein-coupled receptor B1
AFF2 AF4/FMR2 family, member 2
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANGPTL2 angiopoietin-like 2
ARC activity-regulated cytoskeleton-associated protein
ARSD arylsulfatase D
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
C11ORF16 chromosome 11 open reading frame 16
C1ORF61 chromosome 1 open reading frame 61
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAPZB capping protein (actin filament) muscle Z-line, beta
CCL21 chemokine (C-C motif) ligand 21
CCNK cyclin K
CD1E CD1e molecule
CD34 CD34 molecule
CD6 CD6 molecule
CIITA class II, major histocompatibility complex, transactivator
CLEC2B C-type lectin domain family 2, member B
CNTNAP2 contactin associated protein-like 2
CPA4 carboxypeptidase A4
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CUL7 cullin 7
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DIO2 deiodinase, iodothyronine, type II
DPY19L2P2 DPY19L2 pseudogene 2
DUSP1 dual specificity phosphatase 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFNB3 ephrin-B3
ESR1 estrogen receptor 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR176 G protein-coupled receptor 176
GRIP2 glutamate receptor interacting protein 2
GSTA1 glutathione S-transferase alpha 1
HIST1H2AB histone cluster 1, H2ab
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IFT27 intraflagellar transport 27
IL12A interleukin 12A
IL17RC interleukin 17 receptor C
INHBC inhibin, beta C
IRS4 insulin receptor substrate 4
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KANK1 KN motif and ankyrin repeat domains 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLHL22 kelch-like family member 22
KRT9 keratin 9, type I
LHX2 LIM homeobox 2
LMAN1 lectin, mannose-binding, 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MNMIP1 manchette microtubule inner protein 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NIPAL2 NIPA-like domain containing 2
NUMA1 nuclear mitotic apparatus protein 1
NUP214 nucleoporin 214kDa
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OGFR opioid growth factor receptor
PHF14 PHD finger protein 14
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAGL2 pleiomorphic adenoma gene-like 2
PLK3 polo-like kinase 3
PML promyelocytic leukemia
POFUT1 protein O-fucosyltransferase 1
POM121 POM121 transmembrane nucleoporin
POU5F1B POU class 5 homeobox 1B
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTMS parathymosin
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RASA3 RAS p21 protein activator 3
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RXRB retinoid X receptor, beta
SAMD4B sterile alpha motif domain containing 4B
SAYSD1 SAYSVFN motif domain containing 1
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SFRP4 secreted frizzled-related protein 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SP1 Sp1 transcription factor
SRSF7 serine/arginine-rich splicing factor 7
SULT4A1 sulfotransferase family 4A, member 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D22B TBC1 domain family, member 22B
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TICAM1 toll-like receptor adaptor molecule 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMLHE trimethyllysine hydroxylase, epsilon
TP63 tumor protein p63
TRA2A transformer 2 alpha homolog (Drosophila)
TRBC1 T cell receptor beta constant 1
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AFAP1 actin filament associated protein 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANXA2P3 annexin A2 pseudogene 3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARID3B AT rich interactive domain 3B (BRIGHT-like)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BGLAP bone gamma-carboxyglutamate (gla) protein
BST2 bone marrow stromal cell antigen 2
BTF3P12 basic transcription factor 3 pseudogene 12
C10ORF95 chromosome 10 open reading frame 95
C1ORF159 chromosome 1 open reading frame 159
C4BPA complement component 4 binding protein, alpha
C5AR2 complement component 5a receptor 2
CCDC25 coiled-coil domain containing 25
CD80 CD80 molecule
CHRM3 cholinergic receptor, muscarinic 3
CIC capicua transcriptional repressor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL9 cullin 9
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DDIT3 DNA-damage-inducible transcript 3
DMTN dematin actin binding protein
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP13 dual specificity phosphatase 13
ELP6 elongator acetyltransferase complex subunit 6
EMID1 EMI domain containing 1
EPHB6 EPH receptor B6
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGL1 fibrinogen-like 1
FILIP1L filamin A interacting protein 1-like
FXYD5 FXYD domain containing ion transport regulator 5
GK3P glycerol kinase 3 pseudogene
GPR21 G protein-coupled receptor 21
HDAC4 histone deacetylase 4
HIST1H1B histone cluster 1, H1b
HIST1H4C histone cluster 1, H4c
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HYAL2 hyaluronoglucosaminidase 2
IFNA14 interferon, alpha 14
IL12RB1 interleukin 12 receptor, beta 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KRT15 keratin 15, type I
LAMP3 lysosomal-associated membrane protein 3
LARP6 La ribonucleoprotein domain family, member 6
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MID1IP1 MID1 interacting protein 1
MRPL52 mitochondrial ribosomal protein L52
MTA2 metastasis associated 1 family, member 2
NEK11 NIMA-related kinase 11
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOTCH1 notch 1
NPTX1 neuronal pentraxin I
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OTUD3 OTU deubiquitinase 3
OVOL1 ovo-like zinc finger 1
PCNXL4 pecanex-like 4 (Drosophila)
PHC1 polyhomeotic homolog 1 (Drosophila)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PODXL2 podocalyxin-like 2
RPL10L ribosomal protein L10-like
S100A9 S100 calcium binding protein A9
SCGB2A2 secretoglobin, family 2A, member 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNX15 sorting nexin 15
SPRY2 sprouty homolog 2 (Drosophila)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
STON1 stonin 1
TCTN2 tectonic family member 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
WDR62 WD repeat domain 62
ZFP69B ZFP69 zinc finger protein B
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZMAT4 zinc finger, matrin-type 4
ZNF286A zinc finger protein 286A
ZNF35 zinc finger protein 35
ZNF41 zinc finger protein 41
ZNF639 zinc finger protein 639
ZNF747 zinc finger protein 747