| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the citiolone-3930 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARHGAP1 | Rho GTPase activating protein 1 |
| BNC2 | basonuclin 2 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C1ORF95 | chromosome 1 open reading frame 95 |
| CA9 | carbonic anhydrase IX |
| CD8A | CD8a molecule |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLDN18 | claudin 18 |
| COL16A1 | collagen, type XVI, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| COX10 | COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CRISP2 | cysteine-rich secretory protein 2 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CRP | C-reactive protein, pentraxin-related |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DLX2 | distal-less homeobox 2 |
| ELN | elastin |
| ETV7 | ets variant 7 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM182B | family with sequence similarity 182, member B |
| FHL1 | four and a half LIM domains 1 |
| FRMD8 | FERM domain containing 8 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GATA2 | GATA binding protein 2 |
| GIMAP5 | GTPase, IMAP family member 5 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GP6 | glycoprotein VI (platelet) |
| GPR22 | G protein-coupled receptor 22 |
| IL36G | interleukin 36, gamma |
| ING1 | inhibitor of growth family, member 1 |
| INHBE | inhibin, beta E |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KEL | Kell blood group, metallo-endopeptidase |
| KIR3DX1 | killer cell immunoglobulin-like receptor, three domains, X1 |
| KLK15 | kallikrein-related peptidase 15 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 |
| LAT2 | linker for activation of T cells family, member 2 |
| LENEP | lens epithelial protein |
| LOX | lysyl oxidase |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAGEA5 | melanoma antigen family A5 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MST1 | macrophage stimulating 1 |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) |
| MYL10 | myosin, light chain 10, regulatory |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NYNRIN | NYN domain and retroviral integrase containing |
| OR1E1 | olfactory receptor, family 1, subfamily E, member 1 |
| OR2C1 | olfactory receptor, family 2, subfamily C, member 1 |
| ORM1 | orosomucoid 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PART1 | prostate androgen-regulated transcript 1 (non-protein coding) |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDZD2 | PDZ domain containing 2 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POLL | polymerase (DNA directed), lambda |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB6B | RAB6B, member RAS oncogene family |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RECQL5 | RecQ protein-like 5 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| RUSC2 | RUN and SH3 domain containing 2 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SAFB | scaffold attachment factor B |
| SFTPB | surfactant protein B |
| SIRPB1 | signal-regulatory protein beta 1 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SOCS7 | suppressor of cytokine signaling 7 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPON2 | spondin 2, extracellular matrix protein |
| STAC | SH3 and cysteine rich domain |
| STOML1 | stomatin (EPB72)-like 1 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TBCD | tubulin folding cofactor D |
| TEC | tec protein tyrosine kinase |
| TEK | TEK tyrosine kinase, endothelial |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TSC2 | tuberous sclerosis 2 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF154 | zinc finger protein 154 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACPP | acid phosphatase, prostate |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CARTPT | CART prepropeptide |
| CCDC71 | coiled-coil domain containing 71 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDK20 | cyclin-dependent kinase 20 |
| CDK3 | cyclin-dependent kinase 3 |
| CDK6 | cyclin-dependent kinase 6 |
| CDON | cell adhesion associated, oncogene regulated |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CEP295 | centrosomal protein 295kDa |
| CHM | choroideremia (Rab escort protein 1) |
| CIDEB | cell death-inducing DFFA-like effector b |
| CPA4 | carboxypeptidase A4 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRMP1 | collapsin response mediator protein 1 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FLCN | folliculin |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPR1 | G protein-coupled receptor 1 |
| GPR143 | G protein-coupled receptor 143 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HDAC5 | histone deacetylase 5 |
| HIST1H4A | histone cluster 1, H4a |
| HOXA4 | homeobox A4 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT54 | intraflagellar transport 54 |
| IFT81 | intraflagellar transport 81 |
| ITGA8 | integrin, alpha 8 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0319L | KIAA0319-like |
| KRT83 | keratin 83, type II |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAL | mal, T-cell differentiation protein |
| MALL | mal, T-cell differentiation protein-like |
| MDM4 | MDM4, p53 regulator |
| MOB3B | MOB kinase activator 3B |
| MTA2 | metastasis associated 1 family, member 2 |
| MTCP1 | mature T-cell proliferation 1 |
| MX2 | MX dynamin-like GTPase 2 |
| MXD3 | MAX dimerization protein 3 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPY | neuropeptide Y |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OSMR | oncostatin M receptor |
| PCDHB3 | protocadherin beta 3 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PORCN | porcupine homolog (Drosophila) |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RAB40C | RAB40C, member RAS oncogene family |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RNF39 | ring finger protein 39 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TFF2 | trefoil factor 2 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TSC22D4 | TSC22 domain family, member 4 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USP20 | ubiquitin specific peptidase 20 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| XDH | xanthine dehydrogenase |
| YBX2 | Y box binding protein 2 |
| YY2 | YY2 transcription factor |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZNF205 | zinc finger protein 205 |
| ZNF230 | zinc finger protein 230 |
| ZNF532 | zinc finger protein 532 |