citiolone-4311 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the citiolone-4311 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ADAMDEC1 ADAM-like, decysin 1
ADAMTSL4 ADAMTS-like 4
ADGRG1 adhesion G protein-coupled receptor G1
ARSD arylsulfatase D
ATXN8OS ATXN8 opposite strand (non-protein coding)
AVPR1B arginine vasopressin receptor 1B
BMP7 bone morphogenetic protein 7
BMPR1B bone morphogenetic protein receptor, type IB
BTF3P11 basic transcription factor 3 pseudogene 11
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMP cathelicidin antimicrobial peptide
CD52 CD52 molecule
CD82 CD82 molecule
CDK18 cyclin-dependent kinase 18
CDRT1 CMT1A duplicated region transcript 1
CLEC4M C-type lectin domain family 4, member M
COL6A1 collagen, type VI, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPB2 carboxypeptidase B2 (plasma)
CPZ carboxypeptidase Z
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DEPDC5 DEP domain containing 5
DMPK dystrophia myotonica-protein kinase
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DPF1 D4, zinc and double PHD fingers family 1
EPS8L3 EPS8-like 3
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF12 fibroblast growth factor 12
FGF4 fibroblast growth factor 4
FOXD2 forkhead box D2
FRMD1 FERM domain containing 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GPR137 G protein-coupled receptor 137
H2AFX H2A histone family, member X
HBB hemoglobin, beta
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HMGA1 high mobility group AT-hook 1
HRASLS HRAS-like suppressor
HSF1 heat shock transcription factor 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPG2 heparan sulfate proteoglycan 2
IL10 interleukin 10
ITGA7 integrin, alpha 7
KIF1C kinesin family member 1C
KNG1 kininogen 1
LIM2 lens intrinsic membrane protein 2, 19kDa
LOC100131532 uncharacterized LOC100131532
LTBP4 latent transforming growth factor beta binding protein 4
LYZ lysozyme
MCFD2 multiple coagulation factor deficiency 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MPZ myelin protein zero
MSLN mesothelin
MTA1 metastasis associated 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
N4BP1 NEDD4 binding protein 1
NDNF neuron-derived neurotrophic factor
NPIPB15 nuclear pore complex interacting protein family, member B15
NPTX2 neuronal pentraxin II
NPY5R neuropeptide Y receptor Y5
NRCAM neuronal cell adhesion molecule
OLFM1 olfactomedin 1
PASK PAS domain containing serine/threonine kinase
PAX9 paired box 9
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PNMAL1 paraneoplastic Ma antigen family-like 1
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PTPRR protein tyrosine phosphatase, receptor type, R
PXN paxillin
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SFTPB surfactant protein B
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SORBS3 sorbin and SH3 domain containing 3
SPRR3 small proline-rich protein 3
SSX3 synovial sarcoma, X breakpoint 3
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYNJ2 synaptojanin 2
SYT2 synaptotagmin II
TBCD tubulin folding cofactor D
TICAM1 toll-like receptor adaptor molecule 1
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNPO2 transportin 2
TNS4 tensin 4
TRIM3 tripartite motif containing 3
TTLL3 tubulin tyrosine ligase-like family member 3
VPRBP Vpr (HIV-1) binding protein
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZIC3 Zic family member 3
ZNF24 zinc finger protein 24

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACTC1 actin, alpha, cardiac muscle 1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANKRD36 ankyrin repeat domain 36
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
ASAP1-IT1 ASAP1 intronic transcript 1
ATAD5 ATPase family, AAA domain containing 5
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BIRC3 baculoviral IAP repeat containing 3
C17ORF70 chromosome 17 open reading frame 70
C1S complement component 1, s subcomponent
CCDC88C coiled-coil domain containing 88C
CCP110 centriolar coiled coil protein 110kDa
CD3EAP CD3e molecule, epsilon associated protein
CEP295 centrosomal protein 295kDa
CEPT1 choline/ethanolamine phosphotransferase 1
CSRNP3 cysteine-serine-rich nuclear protein 3
DBF4B DBF4 zinc finger B
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
EHF ets homologous factor
ERCC4 excision repair cross-complementation group 4
FAM169A family with sequence similarity 169, member A
FIP1L1 factor interacting with PAPOLA and CPSF1
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSTCD glutathione S-transferase, C-terminal domain containing
H2AFJ H2A histone family, member J
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2BM histone cluster 1, H2bm
HIST1H4C histone cluster 1, H4c
HOXC8 homeobox C8
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INCENP inner centromere protein antigens 135/155kDa
ING4 inhibitor of growth family, member 4
IPP intracisternal A particle-promoted polypeptide
IRAK4 interleukin-1 receptor-associated kinase 4
ITK IL2-inducible T-cell kinase
KIRREL kin of IRRE like (Drosophila)
KLHL28 kelch-like family member 28
MTA2 metastasis associated 1 family, member 2
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NME5 NME/NM23 family member 5
NUTF2 nuclear transport factor 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PER3 period circadian clock 3
PHLDA3 pleckstrin homology-like domain, family A, member 3
PID1 phosphotyrosine interaction domain containing 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PMCH pro-melanin-concentrating hormone
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRRC1 proline-rich coiled-coil 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RPS14P3 ribosomal protein S14 pseudogene 3
SERTAD3 SERTA domain containing 3
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC22A18 solute carrier family 22, member 18
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPIN1 spindlin 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAGLN transgelin
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIPRL TOR signaling pathway regulator
TMC5 transmembrane channel-like 5
TTBK2 tau tubulin kinase 2
TWISTNB TWIST neighbor
UBE2W ubiquitin-conjugating enzyme E2W (putative)
VGLL3 vestigial-like family member 3
WWC2 WW and C2 domain containing 2
XPC xeroderma pigmentosum, complementation group C
XYLT2 xylosyltransferase II
ZBTB38 zinc finger and BTB domain containing 38
ZBTB6 zinc finger and BTB domain containing 6
ZNF184 zinc finger protein 184
ZNF37BP zinc finger protein 37B, pseudogene
ZNF442 zinc finger protein 442
ZNF667 zinc finger protein 667
ZNF668 zinc finger protein 668
ZNF702P zinc finger protein 702, pseudogene
ZNF770 zinc finger protein 770