citiolone-6031 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the citiolone-6031 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACOX2 acyl-CoA oxidase 2, branched chain
ACVR1B activin A receptor, type IB
ADCK4 aarF domain containing kinase 4
AHNAK AHNAK nucleoprotein
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BGN biglycan
CASR calcium-sensing receptor
CASS4 Cas scaffolding protein family member 4
CCDC87 coiled-coil domain containing 87
CD7 CD7 molecule
CDC25C cell division cycle 25C
CDK6 cyclin-dependent kinase 6
CELF2 CUGBP, Elav-like family member 2
CES3 carboxylesterase 3
CHRDL1 chordin-like 1
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CROCC ciliary rootlet coiled-coil, rootletin
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DPP4 dipeptidyl-peptidase 4
DTX3 deltex 3, E3 ubiquitin ligase
DUSP1 dual specificity phosphatase 1
DUSP13 dual specificity phosphatase 13
EBI3 Epstein-Barr virus induced 3
ECE1 endothelin converting enzyme 1
EDA ectodysplasin A
EFNA5 ephrin-A5
ENOX2 ecto-NOX disulfide-thiol exchanger 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPX eosinophil peroxidase
EZR ezrin
FAM46C family with sequence similarity 46, member C
GAS7 growth arrest-specific 7
GGT1 gamma-glutamyltransferase 1
GLP1R glucagon-like peptide 1 receptor
GNRH2 gonadotropin-releasing hormone 2
GSTA3 glutathione S-transferase alpha 3
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOXA11 homeobox A11
HP haptoglobin
HRASLS HRAS-like suppressor
ICOSLG inducible T-cell co-stimulator ligand
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
INTS1 integrator complex subunit 1
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
KIAA0125 KIAA0125
LAMC2 laminin, gamma 2
LIN7A lin-7 homolog A (C. elegans)
LINC01587 long intergenic non-protein coding RNA 1587
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAOB monoamine oxidase B
MAPK14 mitogen-activated protein kinase 14
MAPRE3 microtubule-associated protein, RP/EB family, member 3
METTL7A methyltransferase like 7A
MINK1 misshapen-like kinase 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLXIP MLX interacting protein
MTMR1 myotubularin related protein 1
MYL10 myosin, light chain 10, regulatory
MYOZ1 myozenin 1
OCLM oculomedin
OMG oligodendrocyte myelin glycoprotein
OPCML opioid binding protein/cell adhesion molecule-like
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PCDHGA3 protocadherin gamma subfamily A, 3
PGR progesterone receptor
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PRAMEF11 PRAME family member 11
PRB1 proline-rich protein BstNI subfamily 1
PTAFR platelet-activating factor receptor
PYY peptide YY
RASAL2 RAS protein activator like 2
REG1A regenerating islet-derived 1 alpha
RUNX1 runt-related transcription factor 1
S100A8 S100 calcium binding protein A8
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC35E2 solute carrier family 35, member E2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPTBN5 spectrin, beta, non-erythrocytic 5
STC1 stanniocalcin 1
SYT11 synaptotagmin XI
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TJAP1 tight junction associated protein 1 (peripheral)
TPMT thiopurine S-methyltransferase
TRIL TLR4 interactor with leucine-rich repeats
TRPV4 transient receptor potential cation channel, subfamily V, member 4
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
XYLB xylulokinase homolog (H. influenzae)
ZNF343 zinc finger protein 343

decreased expression

Symbol Name
ACTL8 actin-like 8
ADGRG2 adhesion G protein-coupled receptor G2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASIC1 acid sensing (proton gated) ion channel 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C1QTNF3 C1q and tumor necrosis factor related protein 3
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAPRIN2 caprin family member 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CENPO centromere protein O
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIC capicua transcriptional repressor
CLIP4 CAP-GLY domain containing linker protein family, member 4
COPZ2 coatomer protein complex, subunit zeta 2
CRLF1 cytokine receptor-like factor 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DBF4B DBF4 zinc finger B
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DYSF dysferlin
ELSPBP1 epididymal sperm binding protein 1
ENO3 enolase 3 (beta, muscle)
F2R coagulation factor II (thrombin) receptor
FAM110B family with sequence similarity 110, member B
FAM155B family with sequence similarity 155, member B
FAM169A family with sequence similarity 169, member A
FAM204A family with sequence similarity 204, member A
FBXO31 F-box protein 31
FFAR2 free fatty acid receptor 2
FILIP1L filamin A interacting protein 1-like
FMOD fibromodulin
GADD45G growth arrest and DNA-damage-inducible, gamma
GLS2 glutaminase 2 (liver, mitochondrial)
GPC3 glypican 3
GPR21 G protein-coupled receptor 21
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST2H2AA3 histone cluster 2, H2aa3
HLA-J major histocompatibility complex, class I, J (pseudogene)
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCTD7 potassium channel tetramerization domain containing 7
KLF7 Kruppel-like factor 7 (ubiquitous)
LMX1B LIM homeobox transcription factor 1, beta
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC61 leucine rich repeat containing 61
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBNL3 muscleblind-like splicing regulator 3
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
NDE1 nudE neurodevelopment protein 1
NDOR1 NADPH dependent diflavin oxidoreductase 1
NOL12 nucleolar protein 12
OR1D2 olfactory receptor, family 1, subfamily D, member 2
P3H1 prolyl 3-hydroxylase 1
PAQR6 progestin and adipoQ receptor family member VI
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PQLC2 PQ loop repeat containing 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RFXAP regulatory factor X-associated protein
RNF39 ring finger protein 39
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC17A2 solute carrier family 17, member 2
SLIT2 slit homolog 2 (Drosophila)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
STEAP1 six transmembrane epithelial antigen of the prostate 1
THBS3 thrombospondin 3
TMCC2 transmembrane and coiled-coil domain family 2
TMPRSS4 transmembrane protease, serine 4
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
USP20 ubiquitin specific peptidase 20
VASH1 vasohibin 1
VIPR1 vasoactive intestinal peptide receptor 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VPS9D1 VPS9 domain containing 1
WDR62 WD repeat domain 62
XAB2 XPA binding protein 2
ZBTB44 zinc finger and BTB domain containing 44
ZNF136 zinc finger protein 136
ZNF362 zinc finger protein 362
ZNF428 zinc finger protein 428
ZNF532 zinc finger protein 532
ZNF573 zinc finger protein 573