classical lewy body Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils. (Gene Ontology, GO_0097414)
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Genes

14 proteins co-occuring with the classical lewy body cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
LINGO1 leucine rich repeat and Ig domain containing 1 1.26022
SNCAIP synuclein, alpha interacting protein 0.980016
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.948284
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.810735
RTN4R reticulon 4 receptor 0.794687
CLU clusterin 0.729732
LRRK2 leucine-rich repeat kinase 2 0.703949
TGOLN2 trans-golgi network protein 2 0.620529
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.532078
GBA glucosidase, beta, acid 0.47442
TH tyrosine hydroxylase 0.168847
EGFR epidermal growth factor receptor 0.165932
SYP synaptophysin 0.165463
NPC2 Niemann-Pick disease, type C2 0.158882
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