cleavage Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

224 proteins co-occuring with the biological term cleavage in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACIN1 apoptotic chromatin condensation inducer 1
ACO1 aconitase 1, soluble
ADAM17 ADAM metallopeptidase domain 17
ADD1 adducin 1 (alpha)
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMELY amelogenin, Y-linked
ANXA2 annexin A2
APP amyloid beta (A4) precursor protein
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ATM ATM serine/threonine kinase
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP7B ATPase, Cu++ transporting, beta polypeptide
AURKB aurora kinase B
BACE1 beta-site APP-cleaving enzyme 1
BAD BCL2-associated agonist of cell death
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
BRCA1 breast cancer 1, early onset
C3 complement component 3
C5AR1 complement component 5a receptor 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCNE1 cyclin E1
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDCA8 cell division cycle associated 8
CDCP1 CUB domain containing protein 1
CDK1 cyclin-dependent kinase 1
CDK11B cyclin-dependent kinase 11B
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDX2 caudal type homeobox 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFL1 cofilin 1 (non-muscle)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
COL17A1 collagen, type XVII, alpha 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRMP1 collapsin response mediator protein 1
CSN1S1 casein alpha s1
CSN2 casein beta
CSNK2B casein kinase 2, beta polypeptide
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAP3 death associated protein 3
DCLRE1C DNA cross-link repair 1C
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DES desmin
DLG4 discs, large homolog 4 (Drosophila)
DPYSL2 dihydropyrimidinase-like 2
DROSHA drosha, ribonuclease type III
DSPP dentin sialophosphoprotein
DSTN destrin (actin depolymerizing factor)
ECT2 epithelial cell transforming 2
EGFR epidermal growth factor receptor
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4E eukaryotic translation initiation factor 4E
ERBB2 erb-b2 receptor tyrosine kinase 2
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
EZR ezrin
F5 coagulation factor V (proaccelerin, labile factor)
FES FES proto-oncogene, tyrosine kinase
FGA fibrinogen alpha chain
FLNA filamin A, alpha
FOXO1 forkhead box O1
FURIN furin (paired basic amino acid cleaving enzyme)
G6PC glucose-6-phosphatase, catalytic subunit
GAP43 growth associated protein 43
GAST gastrin
GFAP glial fibrillary acidic protein
GJA8 gap junction protein, alpha 8, 50kDa
GMNN geminin, DNA replication inhibitor
GOLGA3 golgin A3
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPHN gephyrin
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GTF2B general transcription factor IIB
GYS1 glycogen synthase 1 (muscle)
H2AFX H2A histone family, member X
HDGF hepatoma-derived growth factor
HIST1H2BB histone cluster 1, H2bb
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HPSE heparanase
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HTRA2 HtrA serine peptidase 2
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
IFI16 interferon, gamma-inducible protein 16
IL16 interleukin 16
INCENP inner centromere protein antigens 135/155kDa
INSR insulin receptor
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KAT7 K(lysine) acetyltransferase 7
KCNIP3 Kv channel interacting protein 3, calsenilin
KIF23 kinesin family member 23
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LCAT lecithin-cholesterol acyltransferase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LGALS3 lectin, galactoside-binding, soluble, 3
LMNB1 lamin B1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAPT microtubule-associated protein tau
MAX MYC associated factor X
MET MET proto-oncogene, receptor tyrosine kinase
MIP major intrinsic protein of lens fiber
MSN moesin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYL12B myosin, light chain 12B, regulatory
MYL9 myosin, light chain 9, regulatory
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PA2G4 proliferation-associated 2G4, 38kDa
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAM peptidylglycine alpha-amidating monooxygenase
PARK2 parkin RBR E3 ubiquitin protein ligase
PARL presenilin associated, rhomboid-like
PDE4A phosphodiesterase 4A, cAMP-specific
PDIA6 protein disulfide isomerase family A, member 6
PDPK1 3-phosphoinositide dependent protein kinase 1
PENK proenkephalin
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKN1 protein kinase N1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRC1 protein regulator of cytokinesis 1
PRH1 proline-rich protein HaeIII subfamily 1
PRH2 proline-rich protein HaeIII subfamily 2
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCD protein kinase C, delta
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRL prolactin
PSEN1 presenilin 1
PSEN2 presenilin 2
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTRF polymerase I and transcript release factor
PXN paxillin
PYGM phosphorylase, glycogen, muscle
RACGAP1 Rac GTPase activating protein 1
RAD51 RAD51 recombinase
RAD9A RAD9 homolog A (S. pombe)
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RDX radixin
RHO rhodopsin
RPA2 replication protein A2, 32kDa
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RTN4 reticulon 4
SATB1 SATB homeobox 1
SLITRK1 SLIT and NTRK-like family, member 1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNAP25 synaptosomal-associated protein, 25kDa
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SP1 Sp1 transcription factor
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTB spectrin, beta, erythrocytic
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF1 sterol regulatory element binding transcription factor 1
SSB Sjogren syndrome antigen B (autoantigen La)
STAR steroidogenic acute regulatory protein
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STATH statherin
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
SVIL supervillin
SYN1 synapsin I
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAOK2 TAO kinase 2
TARDBP TAR DNA binding protein
THOP1 thimet oligopeptidase 1
TJP1 tight junction protein 1
TLN1 talin 1
TOP1 topoisomerase (DNA) I
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP73 tumor protein p73
TRPM7 transient receptor potential cation channel, subfamily M, member 7
UNG uracil-DNA glycosylase
VIM vimentin
VTN vitronectin
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YY1 YY1 transcription factor
ZYX zyxin