cleaves Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

138 genes co-occuring with the biological term cleaves in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACAN aggrecan
ADAM17 ADAM metallopeptidase domain 17
ADAM28 ADAM metallopeptidase domain 28
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRB1 adhesion G protein-coupled receptor B1
ALOX5 arachidonate 5-lipoxygenase
ALPL alkaline phosphatase, liver/bone/kidney
ASIC1 acid sensing (proton gated) ion channel 1
ATG4A autophagy related 4A, cysteine peptidase
BACE1 beta-site APP-cleaving enzyme 1
BACE2 beta-site APP-cleaving enzyme 2
BAX BCL2-associated X protein
BCO2 beta-carotene oxygenase 2
BID BH3 interacting domain death agonist
BMP1 bone morphogenetic protein 1
C3 complement component 3
C4B complement component 4B (Chido blood group)
CAMP cathelicidin antimicrobial peptide
CAPN1 calpain 1, (mu/I) large subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL11 chemokine (C-C motif) ligand 11
CCL21 chemokine (C-C motif) ligand 21
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CFLAR CASP8 and FADD-like apoptosis regulator
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL7A1 collagen, type VII, alpha 1
CPO carboxypeptidase O
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CROT carnitine O-octanoyltransferase
CTSB cathepsin B
CTSD cathepsin D
CTSG cathepsin G
CTSK cathepsin K
CUX1 cut-like homeobox 1
CYLD cylindromatosis (turban tumor syndrome)
DBR1 debranching RNA lariats 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFB1 defensin, beta 1
DGCR8 DGCR8 microprocessor complex subunit
DROSHA drosha, ribonuclease type III
EGFR epidermal growth factor receptor
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
ELAC2 elaC ribonuclease Z 2
ELANE elastase, neutrophil expressed
EME1 essential meiotic structure-specific endonuclease 1
EPHA2 EPH receptor A2
EXOSC5 exosome component 5
F12 coagulation factor XII (Hageman factor)
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FAN1 FANCD2/FANCI-associated nuclease 1
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGF2 fibroblast growth factor 2 (basic)
FN1 fibronectin 1
FOXO1 forkhead box O1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMM granzyme M (lymphocyte met-ase 1)
HAMP hepcidin antimicrobial peptide
HDAC7 histone deacetylase 7
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HNRNPK heterogeneous nuclear ribonucleoprotein K
HPN hepsin
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTRA1 HtrA serine peptidase 1
HTRA2 HtrA serine peptidase 2
HYAL4 hyaluronoglucosaminidase 4
IDE insulin-degrading enzyme
IGF1 insulin-like growth factor 1 (somatomedin C)
IL13RA2 interleukin 13 receptor, alpha 2
IL18 interleukin 18
IL37 interleukin 37
ISG15 ISG15 ubiquitin-like modifier
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPT microtubule-associated protein tau
MASP2 mannan-binding lectin serine peptidase 2
MAVS mitochondrial antiviral signaling protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MST1 macrophage stimulating 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MUS81 MUS81 structure-specific endonuclease subunit
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NPSA novel prostate-specific antigen
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OTUD7B OTU deubiquitinase 7B
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARL presenilin associated, rhomboid-like
PCNT pericentrin
PINK1 PTEN induced putative kinase 1
PMEL premelanosome protein
PPL periplakin
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRSS8 protease, serine, 8
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
RHBDL2 rhomboid, veinlet-like 2 (Drosophila)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SDC4 syndecan 4
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SPPL3 signal peptide peptidase like 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
TDP1 tyrosyl-DNA phosphodiesterase 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TICAM1 toll-like receptor adaptor molecule 1
TLR3 toll-like receptor 3
TMEM27 transmembrane protein 27
TMPRSS11D transmembrane protease, serine 11D
TMPRSS6 transmembrane protease, serine 6
TNC tenascin C
TP73 tumor protein p73
TPSAB1 tryptase alpha/beta 1
USP21 ubiquitin specific peptidase 21
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VTN vitronectin
VWF von Willebrand factor