| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the clemastine-7443 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APC | adenomatous polyposis coli |
| ATF3 | activating transcription factor 3 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BBS9 | Bardet-Biedl syndrome 9 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CHPF2 | chondroitin polymerizing factor 2 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| EED | embryonic ectoderm development |
| EGR1 | early growth response 1 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FDPS | farnesyl diphosphate synthase |
| FGFR4 | fibroblast growth factor receptor 4 |
| FOXG1 | forkhead box G1 |
| FOXN3 | forkhead box N3 |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| FZD7 | frizzled class receptor 7 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPR137 | G protein-coupled receptor 137 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HDLBP | high density lipoprotein binding protein |
| HFE | hemochromatosis |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMOX1 | heme oxygenase 1 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INSIG1 | insulin induced gene 1 |
| JUN | jun proto-oncogene |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KHNYN | KH and NYN domain containing |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MPDZ | multiple PDZ domain protein |
| MSMO1 | methylsterol monooxygenase 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MVK | mevalonate kinase |
| MXD3 | MAX dimerization protein 3 |
| N4BP3 | NEDD4 binding protein 3 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NF2 | neurofibromin 2 (merlin) |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NNAT | neuronatin |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PLCH1 | phospholipase C, eta 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PSEN2 | presenilin 2 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SGPL1 | sphingosine-1-phosphate lyase 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPATA5L1 | spermatogenesis associated 5-like 1 |
| SSPN | sarcospan |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| SYNRG | synergin, gamma |
| SYT17 | synaptotagmin XVII |
| TMCO3 | transmembrane and coiled-coil domains 3 |
| TOP3A | topoisomerase (DNA) III alpha |
| TRAIP | TRAF interacting protein |
| TRIM2 | tripartite motif containing 2 |
| TUBG2 | tubulin, gamma 2 |
| UBE3B | ubiquitin protein ligase E3B |
| WDR48 | WD repeat domain 48 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| YIPF4 | Yip1 domain family, member 4 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZMYM1 | zinc finger, MYM-type 1 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ALKBH1 | alkB, alkylation repair homolog 1 (E. coli) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CARD8 | caspase recruitment domain family, member 8 |
| CASZ1 | castor zinc finger 1 |
| CBR3 | carbonyl reductase 3 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLDN9 | claudin 9 |
| CLSPN | claspin |
| CRY2 | cryptochrome circadian clock 2 |
| CTSV | cathepsin V |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EPHA4 | EPH receptor A4 |
| ERCC4 | excision repair cross-complementation group 4 |
| EVPL | envoplakin |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXO2 | F-box protein 2 |
| FMO4 | flavin containing monooxygenase 4 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR19 | G protein-coupled receptor 19 |
| GPR27 | G protein-coupled receptor 27 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GRB7 | growth factor receptor-bound protein 7 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4C | histone cluster 1, H4c |
| KIAA0125 | KIAA0125 |
| KIF15 | kinesin family member 15 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAMA5 | laminin, alpha 5 |
| LHX1 | LIM homeobox 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRC49 | leucine rich repeat containing 49 |
| MAP1S | microtubule-associated protein 1S |
| MBNL3 | muscleblind-like splicing regulator 3 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NPY5R | neuropeptide Y receptor Y5 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PCDHB13 | protocadherin beta 13 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLD2 | phospholipase D2 |
| PLXNA3 | plexin A3 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PROCR | protein C receptor, endothelial |
| PRR15L | proline rich 15-like |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| SH2D4A | SH2 domain containing 4A |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SNHG20 | small nucleolar RNA host gene 20 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STBD1 | starch binding domain 1 |
| STXBP1 | syntaxin binding protein 1 |
| TDRD1 | tudor domain containing 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM109 | transmembrane protein 109 |
| TMEM53 | transmembrane protein 53 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM25 | tripartite motif containing 25 |
| TUBA3C | tubulin, alpha 3c |
| UBQLN4 | ubiquilin 4 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VPS9D1 | VPS9 domain containing 1 |
| XAB2 | XPA binding protein 2 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF23 | zinc finger protein 23 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZW10 | zw10 kinetochore protein |
