| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the clemastine-7485 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADCK4 | aarF domain containing kinase 4 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATXN2L | ataxin 2-like |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CPA4 | carboxypeptidase A4 |
| CPQ | carboxypeptidase Q |
| CREM | cAMP responsive element modulator |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DIAPH2 | diaphanous-related formin 2 |
| EGR1 | early growth response 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| FBLN1 | fibulin 1 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FLOT1 | flotillin 1 |
| FOSL2 | FOS-like antigen 2 |
| FRMD1 | FERM domain containing 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GIMAP5 | GTPase, IMAP family member 5 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GLS | glutaminase |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPATCH2L | G patch domain containing 2-like |
| GSTM4 | glutathione S-transferase mu 4 |
| HFE | hemochromatosis |
| HIST1H2BO | histone cluster 1, H2bo |
| INSIG1 | insulin induced gene 1 |
| IRF9 | interferon regulatory factor 9 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KLHL24 | kelch-like family member 24 |
| LAMB1 | laminin, beta 1 |
| LDLR | low density lipoprotein receptor |
| LPIN1 | lipin 1 |
| MED16 | mediator complex subunit 16 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MINK1 | misshapen-like kinase 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MTMR3 | myotubularin related protein 3 |
| MVK | mevalonate kinase |
| NAAA | N-acylethanolamine acid amidase |
| NCOA2 | nuclear receptor coactivator 2 |
| NPC1 | Niemann-Pick disease, type C1 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PHOX2A | paired-like homeobox 2a |
| PLA2G3 | phospholipase A2, group III |
| POFUT2 | protein O-fucosyltransferase 2 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PTAFR | platelet-activating factor receptor |
| RAB40C | RAB40C, member RAS oncogene family |
| RANBP1 | RAN binding protein 1 |
| RCAN1 | regulator of calcineurin 1 |
| RFPL3 | ret finger protein-like 3 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SATB2 | SATB homeobox 2 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SDC3 | syndecan 3 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SFTPC | surfactant protein C |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SNAI2 | snail family zinc finger 2 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STC1 | stanniocalcin 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYN2 | synapsin II |
| SYT13 | synaptotagmin XIII |
| TAC3 | tachykinin 3 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TMC7 | transmembrane channel-like 7 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TRIM2 | tripartite motif containing 2 |
| TRIM21 | tripartite motif containing 21 |
| TROVE2 | TROVE domain family, member 2 |
| TYMS | thymidylate synthetase |
| USP2 | ubiquitin specific peptidase 2 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| YY2 | YY2 transcription factor |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF117 | zinc finger protein 117 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| APOD | apolipoprotein D |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| BAG4 | BCL2-associated athanogene 4 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CCDC15 | coiled-coil domain containing 15 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CERK | ceramide kinase |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCP1A | decapping mRNA 1A |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| FAM63A | family with sequence similarity 63, member A |
| FER | fer (fps/fes related) tyrosine kinase |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXD1 | forkhead box D1 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GHR | growth hormone receptor |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GPR19 | G protein-coupled receptor 19 |
| GRAMD4 | GRAM domain containing 4 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H4F | histone cluster 1, H4f |
| HMGCL | 3-hydroxymethyl-3-methylglutaryl-CoA lyase |
| IL15RA | interleukin 15 receptor, alpha |
| IPO13 | importin 13 |
| KAT2B | K(lysine) acetyltransferase 2B |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KRBOX4 | KRAB box domain containing 4 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC61 | leucine rich repeat containing 61 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| METTL2B | methyltransferase like 2B |
| MTCL1 | microtubule crosslinking factor 1 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NDRG4 | NDRG family member 4 |
| NEO1 | neogenin 1 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| PC | pyruvate carboxylase |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PGR | progesterone receptor |
| PLA2G12A | phospholipase A2, group XIIA |
| PLD2 | phospholipase D2 |
| PODXL2 | podocalyxin-like 2 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RFTN1 | raftlin, lipid raft linker 1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNMTL1 | RNA methyltransferase like 1 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SETD1A | SET domain containing 1A |
| SH2B3 | SH2B adaptor protein 3 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SREK1IP1 | SREK1-interacting protein 1 |
| STK25 | serine/threonine kinase 25 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TRABD | TraB domain containing |
| TRIM66 | tripartite motif containing 66 |
| UBXN6 | UBX domain protein 6 |
| USP21 | ubiquitin specific peptidase 21 |
| USP36 | ubiquitin specific peptidase 36 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF184 | zinc finger protein 184 |
| ZNF8 | zinc finger protein 8 |
