| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the clemizole-2339 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADCY9 | adenylate cyclase 9 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BMP7 | bone morphogenetic protein 7 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CAPRIN2 | caprin family member 2 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCPG1 | cell cycle progression 1 |
| CD47 | CD47 molecule |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CLSTN2 | calsyntenin 2 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COL1A2 | collagen, type I, alpha 2 |
| CPM | carboxypeptidase M |
| CREM | cAMP responsive element modulator |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTC1 | CTS telomere maintenance complex component 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DNASE2 | deoxyribonuclease II, lysosomal |
| DNMBP | dynamin binding protein |
| E2F1 | E2F transcription factor 1 |
| ELK1 | ELK1, member of ETS oncogene family |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| EML2 | echinoderm microtubule associated protein like 2 |
| FAM184A | family with sequence similarity 184, member A |
| FAM3A | family with sequence similarity 3, member A |
| FNDC3A | fibronectin type III domain containing 3A |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GK | glycerol kinase |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| HSF1 | heat shock transcription factor 1 |
| IFT46 | intraflagellar transport 46 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| KAZN | kazrin, periplakin interacting protein |
| LIMD2 | LIM domain containing 2 |
| LIN7C | lin-7 homolog C (C. elegans) |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LPAR2 | lysophosphatidic acid receptor 2 |
| LPPR3 | lipid phosphate phosphatase-related protein type 3 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| NOL12 | nucleolar protein 12 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCNX | pecanex homolog (Drosophila) |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDLIM5 | PDZ and LIM domain 5 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLCG1 | phospholipase C, gamma 1 |
| PLK3 | polo-like kinase 3 |
| POLR3C | polymerase (RNA) III (DNA directed) polypeptide C (62kD) |
| PPAP2A | phosphatidic acid phosphatase type 2A |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAD50 | RAD50 homolog (S. cerevisiae) |
| RBKS | ribokinase |
| RBM19 | RNA binding motif protein 19 |
| RCAN1 | regulator of calcineurin 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RIN3 | Ras and Rab interactor 3 |
| RNF122 | ring finger protein 122 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SRPR | signal recognition particle receptor (docking protein) |
| STXBP1 | syntaxin binding protein 1 |
| SYNGR1 | synaptogyrin 1 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TK2 | thymidine kinase 2, mitochondrial |
| TLE3 | transducin-like enhancer of split 3 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TRIM29 | tripartite motif containing 29 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF354A | zinc finger protein 354A |
| ZNF573 | zinc finger protein 573 |
| ZW10 | zw10 kinetochore protein |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD3 | abhydrolase domain containing 3 |
| ACPP | acid phosphatase, prostate |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ANKRD36 | ankyrin repeat domain 36 |
| ATG9A | autophagy related 9A |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BMP15 | bone morphogenetic protein 15 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDK3 | cyclin-dependent kinase 3 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CISH | cytokine inducible SH2-containing protein |
| CSF1R | colony stimulating factor 1 receptor |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DSE | dermatan sulfate epimerase |
| DSPP | dentin sialophosphoprotein |
| DUSP5 | dual specificity phosphatase 5 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ETV4 | ets variant 4 |
| FILIP1L | filamin A interacting protein 1-like |
| FKBPL | FK506 binding protein like |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GAB2 | GRB2-associated binding protein 2 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR27 | G protein-coupled receptor 27 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HP | haptoglobin |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IRF9 | interferon regulatory factor 9 |
| ITGB7 | integrin, beta 7 |
| JUNB | jun B proto-oncogene |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIF3B | kinesin family member 3B |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| MAPK3 | mitogen-activated protein kinase 3 |
| METTL16 | methyltransferase like 16 |
| METTL2B | methyltransferase like 2B |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MMP9 | matrix metallopeptidase 9 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| MYO19 | myosin XIX |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NIPAL2 | NIPA-like domain containing 2 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| P3H1 | prolyl 3-hydroxylase 1 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PNMA1 | paraneoplastic Ma antigen 1 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
| POR | P450 (cytochrome) oxidoreductase |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RANGRF | RAN guanine nucleotide release factor |
| RCAN3 | RCAN family member 3 |
| RIN1 | Ras and Rab interactor 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF167 | ring finger protein 167 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SLFN12 | schlafen family member 12 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNX15 | sorting nexin 15 |
| SPATA2L | spermatogenesis associated 2-like |
| SPIDR | scaffolding protein involved in DNA repair |
| SREK1IP1 | SREK1-interacting protein 1 |
| STIM1 | stromal interaction molecule 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIGD6 | tigger transposable element derived 6 |
| TMEM134 | transmembrane protein 134 |
| TMEM212 | transmembrane protein 212 |
| TOLLIP | toll interacting protein |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TUBA3C | tubulin, alpha 3c |
| VNN2 | vanin 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF426 | zinc finger protein 426 |
| ZNF480 | zinc finger protein 480 |
| ZNF668 | zinc finger protein 668 |
| ZNF701 | zinc finger protein 701 |
| ZNF747 | zinc finger protein 747 |
| ZNF770 | zinc finger protein 770 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |