clemizole-3672 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the clemizole-3672 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ADAM30 ADAM metallopeptidase domain 30
ADRBK2 adrenergic, beta, receptor kinase 2
ANGPTL4 angiopoietin-like 4
APOC4 apolipoprotein C-IV
ARG1 arginase 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BGN biglycan
BLVRA biliverdin reductase A
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C19ORF73 chromosome 19 open reading frame 73
C21ORF2 chromosome 21 open reading frame 2
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAPN6 calpain 6
CAPN9 calpain 9
CD226 CD226 molecule
CD84 CD84 molecule
CDC14B cell division cycle 14B
CFAP45 cilia and flagella associated protein 45
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CNTD2 cyclin N-terminal domain containing 2
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DHRS12 dehydrogenase/reductase (SDR family) member 12
DOCK9 dedicator of cytokinesis 9
DOK2 docking protein 2, 56kDa
DPF1 D4, zinc and double PHD fingers family 1
EXOSC2 exosome component 2
FAM212B family with sequence similarity 212, member B
GK glycerol kinase
GRIK5 glutamate receptor, ionotropic, kainate 5
GYPB glycophorin B (MNS blood group)
HIP1 huntingtin interacting protein 1
HIST1H2BM histone cluster 1, H2bm
HNF1B HNF1 homeobox B
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HTN1 histatin 1
IL2RG interleukin 2 receptor, gamma
INADL InaD-like (Drosophila)
KIAA0319L KIAA0319-like
KIF17 kinesin family member 17
KRT37 keratin 37, type I
KRTAP1-1 keratin associated protein 1-1
LIMK1 LIM domain kinase 1
LRRN2 leucine rich repeat neuronal 2
MAU2 MAU2 sister chromatid cohesion factor
MBD2 methyl-CpG binding domain protein 2
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MFSD7 major facilitator superfamily domain containing 7
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NEUROD1 neuronal differentiation 1
NPC1 Niemann-Pick disease, type C1
NRN1 neuritin 1
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OTOR otoraplin
PALM paralemmin
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PCSK2 proprotein convertase subtilisin/kexin type 2
PKNOX2 PBX/knotted 1 homeobox 2
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTH2R parathyroid hormone 2 receptor
PYHIN1 pyrin and HIN domain family, member 1
RAB26 RAB26, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RND1 Rho family GTPase 1
RUNDC3A RUN domain containing 3A
S100A1 S100 calcium binding protein A1
SAMD4A sterile alpha motif domain containing 4A
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCN1A sodium channel, voltage gated, type I alpha subunit
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPANXC SPANX family, member C
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPRR3 small proline-rich protein 3
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SURF1 surfeit 1
TDO2 tryptophan 2,3-dioxygenase
TESC tescalcin
TEX15 testis expressed 15
TGM4 transglutaminase 4
THRB thyroid hormone receptor, beta
TOP3B topoisomerase (DNA) III beta
TOR1AIP1 torsin A interacting protein 1
TSPAN9 tetraspanin 9
TTC12 tetratricopeptide repeat domain 12
TTC9 tetratricopeptide repeat domain 9
USP46 ubiquitin specific peptidase 46
VAV3 vav 3 guanine nucleotide exchange factor
ZFP64 ZFP64 zinc finger protein
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
AURKC aurora kinase C
BDKRB1 bradykinin receptor B1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C14ORF79 chromosome 14 open reading frame 79
C17ORF53 chromosome 17 open reading frame 53
C17ORF80 chromosome 17 open reading frame 80
C1ORF21 chromosome 1 open reading frame 21
C1QTNF1 C1q and tumor necrosis factor related protein 1
C8ORF44 chromosome 8 open reading frame 44
CASZ1 castor zinc finger 1
CDHR2 cadherin-related family member 2
CHML choroideremia-like (Rab escort protein 2)
CNTFR ciliary neurotrophic factor receptor
CPNE7 copine VII
CSRNP3 cysteine-serine-rich nuclear protein 3
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DBF4B DBF4 zinc finger B
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DUSP9 dual specificity phosphatase 9
ENO3 enolase 3 (beta, muscle)
ERO1LB ERO1-like beta (S. cerevisiae)
ESM1 endothelial cell-specific molecule 1
GJA8 gap junction protein, alpha 8, 50kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GPR176 G protein-coupled receptor 176
GPR19 G protein-coupled receptor 19
GPRASP1 G protein-coupled receptor associated sorting protein 1
H2AFJ H2A histone family, member J
HOXC11 homeobox C11
HSF2BP heat shock transcription factor 2 binding protein
IDI2-AS1 IDI2 antisense RNA 1
IL11RA interleukin 11 receptor, alpha
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KLF2 Kruppel-like factor 2
KLHL25 kelch-like family member 25
LIMD2 LIM domain containing 2
LIPG lipase, endothelial
LRRK1 leucine-rich repeat kinase 1
MAK male germ cell-associated kinase
MBNL3 muscleblind-like splicing regulator 3
MEFV Mediterranean fever
MEGF8 multiple EGF-like-domains 8
MLYCD malonyl-CoA decarboxylase
MMP3 matrix metallopeptidase 3
MTA2 metastasis associated 1 family, member 2
MTMR11 myotubularin related protein 11
NPFFR1 neuropeptide FF receptor 1
NRTN neurturin
NT5C 5', 3'-nucleotidase, cytosolic
NUP62CL nucleoporin 62kDa C-terminal like
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDZK1 PDZ domain containing 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRF1 perforin 1 (pore forming protein)
PRR15L proline rich 15-like
PRR4 proline rich 4 (lacrimal)
PWAR5 Prader Willi/Angelman region RNA 5
RHBDD3 rhomboid domain containing 3
RNF126P1 ring finger protein 126 pseudogene 1
ROM1 retinal outer segment membrane protein 1
RPAP1 RNA polymerase II associated protein 1
SERGEF secretion regulating guanine nucleotide exchange factor
SETD8 SET domain containing (lysine methyltransferase) 8
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STX17 syntaxin 17
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYCE1L synaptonemal complex central element protein 1-like
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TCTN1 tectonic family member 1
TFCP2L1 transcription factor CP2-like 1
TIPRL TOR signaling pathway regulator
TMEM40 transmembrane protein 40
TPCN1 two pore segment channel 1
TRIM25 tripartite motif containing 25
TRIM9 tripartite motif containing 9
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
WDR33 WD repeat domain 33
WNT7A wingless-type MMTV integration site family, member 7A
YOD1 YOD1 deubiquitinase
ZC3H12A zinc finger CCCH-type containing 12A
ZNF141 zinc finger protein 141
ZNF214 zinc finger protein 214
ZNF702P zinc finger protein 702, pseudogene
ZNF76 zinc finger protein 76
ZNF93 zinc finger protein 93