| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the clemizole-4695 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM8 | ADAM metallopeptidase domain 8 |
| ANK2 | ankyrin 2, neuronal |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATF3 | activating transcription factor 3 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BMP1 | bone morphogenetic protein 1 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNN1 | calponin 1, basic, smooth muscle |
| COL6A1 | collagen, type VI, alpha 1 |
| CPQ | carboxypeptidase Q |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DLC1 | DLC1 Rho GTPase activating protein |
| EFCAB11 | EF-hand calcium binding domain 11 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ELAC2 | elaC ribonuclease Z 2 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FBXO40 | F-box protein 40 |
| FGF20 | fibroblast growth factor 20 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HHAT | hedgehog acyltransferase |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL5RA | interleukin 5 receptor, alpha |
| INHBE | inhibin, beta E |
| KIAA1107 | KIAA1107 |
| KIF1A | kinesin family member 1A |
| KIF25 | kinesin family member 25 |
| KITLG | KIT ligand |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIMK1 | LIM domain kinase 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MED25 | mediator complex subunit 25 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MORC1 | MORC family CW-type zinc finger 1 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NF1 | neurofibromin 1 |
| NKTR | natural killer cell triggering receptor |
| NRP2 | neuropilin 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OLFML2A | olfactomedin-like 2A |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PDE10A | phosphodiesterase 10A |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PGR | progesterone receptor |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLEKHH3 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PLK4 | polo-like kinase 4 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRKCA | protein kinase C, alpha |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RAB3B | RAB3B, member RAS oncogene family |
| RAG2 | recombination activating gene 2 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RPS3A | ribosomal protein S3A |
| RUNX3 | runt-related transcription factor 3 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SIRT5 | sirtuin 5 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SLFN12 | schlafen family member 12 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TLX3 | T-cell leukemia homeobox 3 |
| TRD | T cell receptor delta locus |
| TRPM1 | transient receptor potential cation channel, subfamily M, member 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZNF304 | zinc finger protein 304 |
| ZNF532 | zinc finger protein 532 |
| ZNF750 | zinc finger protein 750 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| AFF4 | AF4/FMR2 family, member 4 |
| ALPK1 | alpha-kinase 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CENPO | centromere protein O |
| CENPQ | centromere protein Q |
| CLDN15 | claudin 15 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM155A | family with sequence similarity 155, member A |
| FAM188A | family with sequence similarity 188, member A |
| FAM63A | family with sequence similarity 63, member A |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FILIP1L | filamin A interacting protein 1-like |
| FLJ22184 | |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAMT | guanidinoacetate N-methyltransferase |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXC8 | homeobox C8 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HYI | hydroxypyruvate isomerase (putative) |
| IL17RA | interleukin 17 receptor A |
| JMJD4 | jumonji domain containing 4 |
| KIAA0895 | KIAA0895 |
| KIFC1 | kinesin family member C1 |
| LAMA3 | laminin, alpha 3 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC257152 | uncharacterized LOC257152 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LYRM9 | LYR motif containing 9 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGC12488 | |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NIPAL2 | NIPA-like domain containing 2 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| OXTR | oxytocin receptor |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PER3 | period circadian clock 3 |
| PMM1 | phosphomannomutase 1 |
| PODXL2 | podocalyxin-like 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| S100A4 | S100 calcium binding protein A4 |
| SAA3P | serum amyloid A3 pseudogene |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| STEAP4 | STEAP family member 4 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THOP1 | thimet oligopeptidase 1 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMC5 | transmembrane channel-like 5 |
| TMC7 | transmembrane channel-like 7 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| USB1 | U6 snRNA biogenesis 1 |
| VASH1 | vasohibin 1 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VAX2 | ventral anterior homeobox 2 |
| WDR76 | WD repeat domain 76 |
| WDR91 | WD repeat domain 91 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZNF16 | zinc finger protein 16 |
| ZNF160 | zinc finger protein 160 |
| ZNF428 | zinc finger protein 428 |
| ZNF652 | zinc finger protein 652 |
| ZNF770 | zinc finger protein 770 |
