clenbuterol-5631 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the clenbuterol-5631 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX1 acyl-CoA oxidase 1, palmitoyl
ADAM2 ADAM metallopeptidase domain 2
ADGRE3 adhesion G protein-coupled receptor E3
AHSP alpha hemoglobin stabilizing protein
ANGPTL2 angiopoietin-like 2
APAF1 apoptotic peptidase activating factor 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ASIC4 acid sensing (proton gated) ion channel family member 4
ATF5 activating transcription factor 5
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCR calcitonin receptor
CARTPT CART prepropeptide
CD48 CD48 molecule
CD86 CD86 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CFHR4 complement factor H-related 4
CHD5 chromodomain helicase DNA binding protein 5
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
COL4A1 collagen, type IV, alpha 1
COLEC12 collectin sub-family member 12
CXCR2 chemokine (C-X-C motif) receptor 2
DAAM2 dishevelled associated activator of morphogenesis 2
DCTN1 dynactin 1
DCTN2 dynactin 2 (p50)
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DIAPH2-AS1 DIAPH2 antisense RNA 1
DUOX2 dual oxidase 2
EVA1B eva-1 homolog B (C. elegans)
EXOSC2 exosome component 2
FAM124B family with sequence similarity 124B
FBLN1 fibulin 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FRMPD1 FERM and PDZ domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAST gastrin
GRIP2 glutamate receptor interacting protein 2
HHLA1 HERV-H LTR-associating 1
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HSF4 heat shock transcription factor 4
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGLV3-19 immunoglobulin lambda variable 3-19
IL1RAP interleukin 1 receptor accessory protein
ING4 inhibitor of growth family, member 4
INHA inhibin, alpha
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KSR1 kinase suppressor of ras 1
LHX2 LIM homeobox 2
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
METTL7A methyltransferase like 7A
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLXIP MLX interacting protein
MMP25 matrix metallopeptidase 25
MTCP1 mature T-cell proliferation 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NDRG2 NDRG family member 2
NPY2R neuropeptide Y receptor Y2
OCLM oculomedin
PALM paralemmin
PDE4A phosphodiesterase 4A, cAMP-specific
PLSCR2 phospholipid scramblase 2
PLXNA2 plexin A2
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PRDM1 PR domain containing 1, with ZNF domain
PSG3 pregnancy specific beta-1-glycoprotein 3
PSG4 pregnancy specific beta-1-glycoprotein 4
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RTCA RNA 3'-terminal phosphate cyclase
RYR1 ryanodine receptor 1 (skeletal)
SCRG1 stimulator of chondrogenesis 1
SH3PXD2A SH3 and PX domains 2A
SNX1 sorting nexin 1
SPAG6 sperm associated antigen 6
SPDEF SAM pointed domain containing ETS transcription factor
SPTB spectrin, beta, erythrocytic
TAPBP TAP binding protein (tapasin)
TRIM10 tripartite motif containing 10
TRIM29 tripartite motif containing 29
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSNAXIP1 translin-associated factor X interacting protein 1
UBA7 ubiquitin-like modifier activating enzyme 7
UBOX5 U-box domain containing 5
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VEGFB vascular endothelial growth factor B
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YOD1 YOD1 deubiquitinase
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
ALOX15 arachidonate 15-lipoxygenase
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARID3B AT rich interactive domain 3B (BRIGHT-like)
AUTS2 autism susceptibility candidate 2
BFSP1 beaded filament structural protein 1, filensin
C14ORF79 chromosome 14 open reading frame 79
C5ORF45 chromosome 5 open reading frame 45
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD34 CD34 molecule
CDK20 cyclin-dependent kinase 20
CHKB choline kinase beta
CHRM3 cholinergic receptor, muscarinic 3
CLGN calmegin
CNR2 cannabinoid receptor 2 (macrophage)
COPZ2 coatomer protein complex, subunit zeta 2
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRY2 cryptochrome circadian clock 2
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DEAF1 DEAF1 transcription factor
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSCAM Down syndrome cell adhesion molecule
EPN1 epsin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FGD1 FYVE, RhoGEF and PH domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
GAREM GRB2 associated, regulator of MAPK1
GJA8 gap junction protein, alpha 8, 50kDa
GMPR guanosine monophosphate reductase
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GSTTP1 glutathione S-transferase theta pseudogene 1
HIST1H4E histone cluster 1, H4e
HMOX1 heme oxygenase 1
HOXC4 homeobox C4
IL2RB interleukin 2 receptor, beta
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCTD17 potassium channel tetramerization domain containing 17
LINC00597 long intergenic non-protein coding RNA 597
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRC61 leucine rich repeat containing 61
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAL mal, T-cell differentiation protein
MALL mal, T-cell differentiation protein-like
MED15 mediator complex subunit 15
MFAP2 microfibrillar-associated protein 2
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MYL5 myosin, light chain 5, regulatory
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEK11 NIMA-related kinase 11
NKAIN1 Na+/K+ transporting ATPase interacting 1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PHEX phosphate regulating endopeptidase homolog, X-linked
PIDD1 p53-induced death domain protein 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POU4F2 POU class 4 homeobox 2
PPT2 palmitoyl-protein thioesterase 2
PRB3 proline-rich protein BstNI subfamily 3
PRPH peripherin
PRR4 proline rich 4 (lacrimal)
PRSS16 protease, serine, 16 (thymus)
PTK6 protein tyrosine kinase 6
QPCT glutaminyl-peptide cyclotransferase
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RFXAP regulatory factor X-associated protein
RHOBTB2 Rho-related BTB domain containing 2
RNF39 ring finger protein 39
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNDC3B RUN domain containing 3B
SCARA3 scavenger receptor class A, member 3
SCD5 stearoyl-CoA desaturase 5
SH2D4A SH2 domain containing 4A
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLIT2 slit homolog 2 (Drosophila)
SLMO1 slowmo homolog 1 (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFF2 trefoil factor 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM53 transmembrane protein 53
TNS2 tensin 2
TOM1 target of myb1 (chicken)
TRIM36 tripartite motif containing 36
VASH2 vasohibin 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF286A zinc finger protein 286A
ZNF304 zinc finger protein 304
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF747 zinc finger protein 747
ZNF750 zinc finger protein 750
ZNF862 zinc finger protein 862