clindamycin-1373 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the clindamycin-1373 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ADRA2B adrenoceptor alpha 2B
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGRN agrin
ALX3 ALX homeobox 3
ANKRD12 ankyrin repeat domain 12
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
BIRC7 baculoviral IAP repeat containing 7
C7ORF43 chromosome 7 open reading frame 43
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CAMKV CaM kinase-like vesicle-associated
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CLCF1 cardiotrophin-like cytokine factor 1
CLTA clathrin, light chain A
CNTFR ciliary neurotrophic factor receptor
COL18A1 collagen, type XVIII, alpha 1
COMT catechol-O-methyltransferase
CORT cortistatin
CPM carboxypeptidase M
CPNE7 copine VII
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAH7 dynein, axonemal, heavy chain 7
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DUSP26 dual specificity phosphatase 26 (putative)
ECE1 endothelin converting enzyme 1
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGF4 fibroblast growth factor 4
FGFR1 fibroblast growth factor receptor 1
FOXC1 forkhead box C1
GAP43 growth associated protein 43
GIPC1 GIPC PDZ domain containing family, member 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJB1 gap junction protein, beta 1, 32kDa
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
HAMP hepcidin antimicrobial peptide
HNF1A HNF1 homeobox A
HOXB1 homeobox B1
HOXB5 homeobox B5
HOXC4 homeobox C4
IGHA1 immunoglobulin heavy constant alpha 1
ING1 inhibitor of growth family, member 1
IQCC IQ motif containing C
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIF25 kinesin family member 25
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
LIMS2 LIM and senescent cell antigen-like domains 2
METTL7A methyltransferase like 7A
MOB3B MOB kinase activator 3B
MRC2 mannose receptor, C type 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYF6 myogenic factor 6 (herculin)
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
NCR2 natural cytotoxicity triggering receptor 2
NIPAL2 NIPA-like domain containing 2
OMG oligodendrocyte myelin glycoprotein
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLCG1 phospholipase C, gamma 1
PLD2 phospholipase D2
POMT2 protein-O-mannosyltransferase 2
PPARA peroxisome proliferator-activated receptor alpha
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PRB1 proline-rich protein BstNI subfamily 1
PRB3 proline-rich protein BstNI subfamily 3
PRLH prolactin releasing hormone
PRODH2 proline dehydrogenase (oxidase) 2
PTN pleiotrophin
RAB2A RAB2A, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RET ret proto-oncogene
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPL7 ribosomal protein L7
RRP1B ribosomal RNA processing 1B
SAMD14 sterile alpha motif domain containing 14
SCN5A sodium channel, voltage gated, type V alpha subunit
SH2B1 SH2B adaptor protein 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SPDEF SAM pointed domain containing ETS transcription factor
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBX1 T-box 1
TMCC2 transmembrane and coiled-coil domain family 2
TMEM212 transmembrane protein 212
TNK2 tyrosine kinase, non-receptor, 2
TRIM29 tripartite motif containing 29
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TYR tyrosinase
UBQLN4 ubiquilin 4
UBTD1 ubiquitin domain containing 1
VGF VGF nerve growth factor inducible
VIPR2 vasoactive intestinal peptide receptor 2
WFDC8 WAP four-disulfide core domain 8
ZFHX2 zinc finger homeobox 2
ZNF444 zinc finger protein 444

decreased expression

Symbol Name
ABT1 activator of basal transcription 1
ADAM15 ADAM metallopeptidase domain 15
ANKRD40 ankyrin repeat domain 40
APOC2 apolipoprotein C-II
ARL4A ADP-ribosylation factor-like 4A
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ASTE1 asteroid homolog 1 (Drosophila)
AVEN apoptosis, caspase activation inhibitor
BIN2 bridging integrator 2
BST1 bone marrow stromal cell antigen 1
BYSL bystin-like
C11ORF49 chromosome 11 open reading frame 49
CCDC53 coiled-coil domain containing 53
CCNL2 cyclin L2
CDCA3 cell division cycle associated 3
CDCA8 cell division cycle associated 8
COG7 component of oligomeric golgi complex 7
COMMD9 COMM domain containing 9
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DCXR dicarbonyl/L-xylulose reductase
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DPF2 D4, zinc and double PHD fingers family 2
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EMC9 ER membrane protein complex subunit 9
ERCC2 excision repair cross-complementation group 2
FKTN fukutin
FZD2 frizzled class receptor 2
GALE UDP-galactose-4-epimerase
GBAP1 glucosidase, beta, acid pseudogene 1
GOLGA3 golgin A3
GOLPH3L golgi phosphoprotein 3-like
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
H1FX H1 histone family, member X
IFITM3 interferon induced transmembrane protein 3
ITFG1 integrin alpha FG-GAP repeat containing 1
JOSD1 Josephin domain containing 1
JUNB jun B proto-oncogene
KEAP1 kelch-like ECH-associated protein 1
KLHL21 kelch-like family member 21
LINC00339 long intergenic non-protein coding RNA 339
LPCAT1 lysophosphatidylcholine acyltransferase 1
MCRS1 microspherule protein 1
MGMT O-6-methylguanine-DNA methyltransferase
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPG N-methylpurine-DNA glycosylase
MPV17 MpV17 mitochondrial inner membrane protein
MRPS2 mitochondrial ribosomal protein S2
MSRB1 methionine sulfoxide reductase B1
MTG1 mitochondrial ribosome-associated GTPase 1
MYLIP myosin regulatory light chain interacting protein
NADSYN1 NAD synthetase 1
NAGK N-acetylglucosamine kinase
NRBP1 nuclear receptor binding protein 1
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1
NVL nuclear VCP-like
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
ORC1 origin recognition complex, subunit 1
PCTP phosphatidylcholine transfer protein
PGS1 phosphatidylglycerophosphate synthase 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PPIEL peptidylprolyl isomerase E-like pseudogene
PPP4C protein phosphatase 4, catalytic subunit
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PTOV1 prostate tumor overexpressed 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB4B RAB4B, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM10 RNA binding motif protein 10
SAC3D1 SAC3 domain containing 1
SCNM1 sodium channel modifier 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIAH2 siah E3 ubiquitin protein ligase 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SMG9 SMG9 nonsense mediated mRNA decay factor
SNX17 sorting nexin 17
SNX6 sorting nexin 6
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TEX264 testis expressed 264
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM106C transmembrane protein 106C
TMEM184B transmembrane protein 184B
TRAPPC12 trafficking protein particle complex 12
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TST thiosulfate sulfurtransferase (rhodanese)
TXLNA taxilin alpha
UBE2M ubiquitin-conjugating enzyme E2M
USP39 ubiquitin specific peptidase 39
VILL villin-like
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
WDR6 WD repeat domain 6